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Isolation and Culture of Pig Epiblast Stem Cells
2013Regulation of early development can be directly interrogated in the embryo or can be studied in cultured cells isolated in the laboratory. New understanding of the developmental stages and the signalling requirements of the pig embryo have enabled the development of improved protocols for the derivation of pluripotent cells from early epiblasts.
Aida, Rodriguez +2 more
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NOGGIN Transport in a Model Human Epiblast
2021A thesis presented to the faculty of The Rockefeller University in partial fulfillment of the requirements for the degree of Doctor of ...
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Ultrastructural and immunohistochemical characterization of the bovine epiblast.
Biology of reproduction, 2005The epiblast represents the final embryonic founder cell population with the potential for giving rise to all cell types of the adult body. The pluripotency of the epiblast is lost during the process of gastrulation. Large animal species have a lack of specific markers for pluripotency.
Vejlsted, Morten +5 more
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Ultrastructure of Auxin-Induced Tumors of the Coleorhiza-Epiblast of Wheat
American Journal of Botany, 1975When wheat is germinated in high concentrations of certain auxins, the coleorhiza‐epiblast grows in an excessive and disorganized manner and resembles a callus. Wheat was germinated in 10−3 M indoleacetic acid or in water. There was greater net synthesis of DNA, RNA, and protein in the tumor tissue than in control tissue.
Patricia L, Walne +2 more
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Embryonic development: Tracing the origin of epiblast cells
Current BiologyThe epiblast is the source of all the cells of our bodies and of the pluripotent embryonic stem cells. Novel work using fluorescent reporter-based cell tracking supports a stochastic mechanism for epiblast differentiation and reveals SOX2 as the most obvious marker.
Violaine, Paulus, Claire, Chazaud
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The Epiblast and Pluripotent Stem Cell Lines
All somatic cells develop from the epiblast, which occupies the upper layer of two-layered embryos and in most mammals is formed after the implantation stage but before gastrulation initiates. Once the epiblast is established, the epiblast cells begin to develop into various somatic cells via large-scale cell reorganization, namely, gastrulation ...openaire +2 more sources
Control of epiblast cell fate by mechanical cues
Summary In amniotes, embryonic tissues originate from multipotent epiblast cells, arranged in a mosaic of presumptive territories. How these domains fated to specific lineages become segregated during body formation remains poorly understood.Charlène Guillot +3 more
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Human Naive Epiblast Cells Possess Unrestricted Lineage Potential
Cell Stem Cell, 2021Austin Smith, Ge Guo, Jennifer Nichols
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Human Epiblast Lumenogenesis: From a Cell Aggregate to a Lumenal Cyst
Seminars in Cell and Developmental Biology, 2022Mara C. Duncan +2 more
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Trophectoderm Mechanics Direct Epiblast Shape Upon Embryo Implantation
Cell Reports, 2021Magdalena Żernicka-Goetz +1 more
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