Results 251 to 260 of about 5,134,709 (287)

Dedifferentiation of epidermal cells to stem cells in vivo

The Lancet, 2001
The effects of growth factors on wound healing have been studied extensively; however epidermal regeneration is not fully understood. We treated eight patients with leg ulcers with recombinant human epidermal growth factor (rhEGF) and compared biopsies of regenerating epidermis with those of controls who did not receive rhEGF.
X, Fu, X, Sun, X, Li, Z, Sheng
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The multifaceted adult epidermal stem cell

Current Opinion in Cell Biology, 2003
Adult epidermal stem cells renew the epithelial compartment of the skin throughout life and are the most accessible of all adult stem cells. Most importantly, epidermal stem cells can be efficiently cultivated and transplanted, a significant advantage for cell and gene therapy.
Gambardella L, Barrandon Y
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Epidermal stem cells in culture

Journal of Cell Science, 1988
ABSTRACT Cultures of human epidermal keratinocytes retain many of the characteristics of the tissue from which they are derived, and are therefore useful as an experimental model for studying stem cell properties. The cultures provide evidence that the mechanisms regulating keratinocyte proliferation are complex.
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Transcriptional Control of Epidermal Stem Cells

2013
Transcriptional regulation is fundamentally important for the progression of tissue stem cells through different stages of development and differentiation. Mammalian skin epidermis is an excellent model system to study such regulatory mechanisms due to its easy accessibility, stereotypic spatial arrangement, and availability of well-established cell ...
Briana, Lee, Xing, Dai
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Epidermal Stem Cells

2019
A multilayered epithelium to fulfil its function must be replaced throughout the lifespan. This is possible due to the presence of multipotent, self-renewing epidermal stem cells that give rise to differentiated cell lineages: keratinocytes, hairs, as well as sebocytes.
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Isolation and Cultivation of Epidermal (Stem) Cells

2018
Recent studies have shown that epidermal stem cells derived from the epidermis of are able to form hair follicles in the presence of hair follicle-inducing cells. Here we describe the method that we have used to isolate and cultivate epidermal stem cells.
Xusheng, Wang, Shiyang, Dong, Yaojiong, Wu   +2 more
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[Progress in epidermal stem cells].

Yi chuan = Hereditas, 2010
Mammalian skin epidermis contains different epidermal stem cell pools which contribute to the homeostasis and repair of skin epithelium. Epidermal stem cells possess two essential features common to all stem cells: self-renewal and differentiation.
Li-Juan, Wang, You-Liang, Wang, Xiao, Yang   +2 more
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[Epidermal stem cells].

Bulletin et memoires de l'Academie royale de medecine de Belgique, 2007
info:eu-repo/semantics ...
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Contribution of stem cells and differentiated cells to epidermal tumours

Nature Reviews Cancer, 2003
The outer covering of the skin--the epidermis--is subject to sustained environmental assaults. As a result, many cells acquire potentially oncogenic mutations. Most cells are lost through differentiation, and only long-term epidermal residents, such as stem cells, accumulate the number of genetic hits that are necessary for tumour development. So, what
David M, Owens, Fiona M, Watt
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Epidermal Stem Cells and Dermal–Epidermal Junction

2019
Aging of mammalian skin results from two distinct biological processes: intrinsic and extrinsic mechanisms of skin aging. Exposure to solar ultraviolet (UV) radiation (photoaging) is the major extrinsic assault accelerating the normal aging process. The epidermis constitutes the outermost layer of the skin and thus is constantly challenged by harmful ...
Monique Aumailley, Catherin Niemann
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