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The epidermal stem cell: an overview
Seminars in Developmental Biology, 1993Abstract The epidermis, the intestinal epithelium and the bone marrow are constantly renewed. Once a terminally differentiated cell has fulfilled its function, it is eliminated. Thus, new differentiated cells need to be constantly produced by the proliferative compartment to ensure the function of the tissue.
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The Contribution of Epidermal Stem Cells to Skin Cancer
Stem Cell Reviews, 2005Tumors arising from the skin are of multiple phenotypes, with differing degrees of malignant potential. In mouse models of skin carcinogenesis, tumors of squamous phenotype are the most common; however, human disease indicates that multiple phenotypes may arise from a common pool of stem cells that are then influenced by epigenetic factors.
Michael J, Gerdes, Stuart H, Yuspa
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In Search of the Elusive Epidermal Stem Cell
2006Recent studies are beginning to reveal that our basic concepts of epidermal stem cell biology may be based on somewhat tenuous ground. For example, it is often assumed that colony-forming cells represent epidermal stem cells, although this has not proved to be the case in hematopoietic cell lineages.
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Epidermal keratinocyte stem cells: their maintenance and regulation
Seminars in Cell Biology, 1992The epidermis is a stratified epithelium consisting of interfollicular regions and appendages (hair follicles, sweat glands, sebaceous glands). The dominant cell type (the keratinocyte) is arranged in groups of cells termed epidermal proliferative units (EPUs), and one centrally-located clonogenic stem cell is ultimately responsible for replacing the ...
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Epidermal Development in Mammals: Key Regulators, Signals from Beneath, and Stem Cells
International Journal of Molecular Sciences, 2013En-Kui Duan, Huishan Zhang
exaly
Epidermal Stem Cells in Skin Wound Healing
Advances in Wound Care, 2017Xiaoyang Wu, Xuewen Gou
exaly
Effects of Wnt3a on proliferation and differentiation of human epidermal stem cells
Biochemical and Biophysical Research Communications, 2008Sha Peng, Juxue Li, En-Kui Duan
exaly
Calcitonin gene-related peptide regulates the growth of epidermal stem cells in vitro
Peptides, 2010Yanling He
exaly
Concise Review: Wnt Signaling Pathways in Skin Development and Epidermal Stem Cells
Stem Cells, 2018Lien Wen-Hui, Christopher Lang
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OPINION Epidermal homeostasis: do committed progenitors work while stem cells sleep?
Nature Reviews Molecular Cell Biology, 2008Benjamin Simons, Philip Jones
exaly

