Epidermolysis bullosa acquisita. [PDF]
An Bras Dermatol, 2022 Epidermolysis bullosa acquisita is a rare autoimmune disease, characterized by the synthesis of anti-collagen VII autoantibodies, the main component of hemidesmosome anchoring fibrils. The antigen-antibody binding elicits a complex inflammatory response, which culminates in the loss of dermo-epidermal adhesion of the skin and/or mucous membranes.
Miyamoto D +3 more
europepmc +8 more sources
Epidermolysis Bullosa Acquisita: The 2019 Update [PDF]
Frontiers in Medicine, 2019 Epidermolysis bullosa acquisita (EBA) is an orphan autoimmune disease. Patients with EBA suffer from chronic inflammation as well as blistering and scarring of the skin and mucous membranes.
Hiroshi Koga +5 more
doaj +6 more sources
Epidermolysis bullosa acquisita [PDF]
Vestnik Dermatologii i Venerologii, 2017 The article describes present-day information on the pathogenesis, clinical picture, treatment and differential diagnostics of epidermolysis bullosa acquisita, an autoimmune skin disease caused by the production of anti-Type VII collagen autoantibodies ...
V. V. Chikin +3 more
doaj +8 more sources
Epidermolysis bullosa acquisita treated with ustekinumab: A case report [PDF]
SAGE Open Medical Case Reports, 2022 Epidermolysis bullosa acquisita is a rare autoimmune disease involving cutaneous blistering and scarring associated with collagen VII autoantibodies.
Connor Prosty +4 more
doaj +2 more sources
Case Report: Diagnostic and Therapeutic Challenges in Severe Mechanobullous Epidermolysis Bullosa Acquisita [PDF]
Frontiers in Immunology, 2022 Collagen VII is the main constituent of the anchoring fibrils, important adhesive structures that attach the epidermis to the dermal extracellular matrix.
Franziska Schauer +9 more
doaj +2 more sources
Monocyte populations are involved in the pathogenesis of experimental epidermolysis bullosa acquisita [PDF]
Frontiers in Immunology, 2023 Monocytes play a significant role in the pathogenesis of most inflammatory diseases, including autoimmune diseases. Herein, different subpopulations of monocytes often play differential, partially antagonistic roles, in the regulation of tissue ...
Reza Akbarzadeh +7 more
doaj +2 more sources
Acute renal failure in a patient with epidermolysis bullosa acquisita [PDF]
Anais Brasileiros de Dermatologia, 2017 : Epidermolysis bullosa acquisita is a severe autoimmune subepidermal bullous disease. In this report, we described for the first time a patient with epidermolysis bullosa acquisita who developed acute renal failure.
Guowei Zhao, Qing Yang, Furen Zhang
doaj +2 more sources
Pathological Relevance of Anti-Hsp70 IgG Autoantibodies in Epidermolysis Bullosa Acquisita [PDF]
Frontiers in Immunology, 2022 Stress-induced heat shock protein 70 (Hsp70) is a key intra- and extracellular molecular chaperone implicated in autoimmune processes. Highly immunogenic extracellular Hsp70 can activate innate and acquired (adaptive) immune responses driving the ...
Stefan Tukaj +6 more
doaj +2 more sources
Luteolin peracetate and gossypolone inhibit immune complex-mediated neutrophil activation in vitro and dermal-epidermal separation in an ex vivo model of epidermolysis bullosa acquisita [PDF]
Frontiers in Immunology, 2023 IntroductionNatural products have been shown to an important source of therapeutics for human disease. In this study, we aimed to identify natural compounds as potential therapeutics for epidermolysis bullosa acquisita (EBA), an autoimmune disease caused
Kai Yang +7 more
doaj +2 more sources
Consensus on the treatment of autoimmune bullous dermatoses: bullous pemphigoid, mucous membrane pemphigoid and epidermolysis bullosa acquisita - Brazilian Society of Dermatology [PDF]
Anais Brasileiros de Dermatologia, 2019 : Bullous pemphigoid, mucous membrane pemphigoid and epidermolysis bullosa acquisita are subepidermal autoimmune blistering diseases whose antigenic target is located at the basement membrane zone.
Claudia Giuli Santi +6 more
doaj +2 more sources