Results 31 to 40 of about 576 (142)

Case report: A case of epidermolysis bullosa acquisita with IgG and IgM anti-basement membrane zone antibodies relapsed after COVID-19 mRNA vaccination

Frontiers in Medicine, 2023
We report a case of autoimmune bullous disease (AIBD) with IgG and IgM autoantibodies against epidermal basement membrane zone (BMZ), which showed recurrence of mucocutaneous lesions after coronavirus disease 2019 (COVID-19) mRNA vaccination.
Satoko Minakawa, Satoko Minakawa, Yasushi Matsuzaki, Shogo Yao, Chihiro Sagara, Eijiro Akasaka, Hiroshi Koga, Norito Ishii, Takashi Hashimoto, Daisuke Sawamura   +9 more
doaj   +1 more source

A Case of Bullous Skin Disease Presenting with Odynophagia: A Diagnostic Challenge

Case Reports in Dermatological Medicine, 2016
We report a case of Epidermolysis Bullosa Acquisita (EBA) that presented as a diagnostic challenge. A 60-year-old Qatari lady presented with odynophagia, oral ulceration, and weight loss.
G. Kravvas, D. Veitch, C. M. Perrett
doaj   +1 more source

Preventive but Not Therapeutic Topical Application of Local Anesthetics Can Inhibit Experimental Epidermolysis Bullosa Acquisita in Mice

Frontiers in Immunology, 2021
Epidermolysis bullosa acquisita (EBA) is an autoimmune blistering disorder characterized and caused by autoantibodies against type VII collagen (COL7).
Lifang Wen, Lifang Wen, Xiaoru Dong, Xiaoru Dong, Qing Li, Gabriele Schramm, Bing Zhang, Detlef Zillikens, Ralf J. Ludwig, Frank Petersen, Xinhua Yu   +10 more
doaj   +1 more source

Expression of the α6β4 Integrin in Lesional Skin Differentiates Bullous Pemphigoid (BP) from Epidermolysis Bullosa Acquisita (EBA)

Journal of Investigative Dermatology, 1992
The integrin alpha 6 beta 4 complex is a protein of the membrane of basal keratinocytes, localized at the surface of cells in contact with the basement membrane zone in normal skin. The expression of alpha 6 beta 4 was investigated in several autoimmune blistering skin diseases including bullous pemphigoid (BP), epidermolysis bullosa acquisita (EBA ...
H. Michalaki, M. J. Staquet, A. Cerri, E. Berti, P. Roche, P. Machado, J. F. Nicolas   +6 more
openaire   +3 more sources

Epidermolysis Bullosa Acquisita in Children: Case Series

Вопросы современной педиатрии, 2019
Background. Epidermolysis bullosa acquisita (EBA) is chronic disease accompanied with subepidermal blistering on skin and mucous membranes as a result of autoimmune aggression to type VII collagen.
Nikolay N. Murashkin, Leonid A. Opryatin, Alexander I. Materikin, Eduard T. Ambarchyan, Roman V. Epishev, Maria A. Nefedova   +5 more
doaj   +1 more source

Therapeutic effects of Fc gamma RIV inhibition are mediated by selectively blocking immune complex-induced neutrophil activation in epidermolysis bullosa acquisita

Frontiers in Immunology, 2022
Epidermolysis bullosa acquisita (EBA) is a subepidermal autoimmune bullous disease caused by autoantibodies targeting type VII collagen (COL7). It is characterized by inflammation and subepidermal blistering mainly through immune complex (IC)-mediated ...
Swantje C. Haeger, Khalaf Kridin, Khalaf Kridin, Mario Pieper, Laura Griewahn, Falk Nimmerjahn, Detlef Zillikens, Detlef Zillikens, Peter König, Ralf J. Ludwig, Ralf J. Ludwig, Jennifer E. Hundt   +11 more
doaj   +1 more source

IgM-mediated epidermolysis bullosa acquisita [PDF]

JAAD Case Reports
Sidney Harrison, BS, Vita Mayes, PA-C, MSc, MPH, MMSc, Conrad Brimhall, MD, Roy King, MD   +3 more
doaj   +2 more sources

The G Protein-Coupled Receptor (GPR) 15 Counteracts Antibody-Mediated Skin Inflammation

Frontiers in Immunology, 2020
The G protein-coupled receptor 15 (GPR15) has recently been highlighted as an important regulator of T cell trafficking into the gut under physiological and pathophysiological conditions.
Lina Jegodzinski, Tanya Sezin, Karin Loser, Sadegh Mousavi, Detlef Zillikens, Detlef Zillikens, Christian D. Sadik, Christian D. Sadik   +7 more
doaj   +1 more source

Molecular cloning and characterization of a cDNA encoding canine type VII collagen non-collagenous (NC1) domain, the target antigen of autoimmune disease epidermolysis bullosa acquisita (EBA)

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 1998
Type VII collagen, the major component of anchoring fibrils, serves as tight adhesion of skin basement membrane zone (BMZ) through its amino-terminal non-collagenous (NC1) domain. The NC1 domain is targeted by autoantibodies of an acquired blistering skin disease termed epidermolysis bullosa acquisita (EBA) naturally occurring in humans and dogs.
Xu, Luting, Chen, Mei, Peng, Jun, O’Toole, Edel A., Woodley, David T., Chan, Lawrence S.   +5 more
openaire   +2 more sources

European S2k guidelines on management of autoimmune blistering diseases in children and adolescents

Journal of the European Academy of Dermatology and Venereology, Volume 40, Issue 7, Page 1137-1161, July 2026.
Autoimmune blistering disorders (AIBDs) in children are rare, challenging to diagnose and treat and often require immunosuppressants. Until now, no paediatric care guidelines existed. The EADV Task Force for AIBDs has developed the consensus‐based recommendations, enabling physicians to adopt a uniform, tailored treatment strategy to improve outcomes ...
A. Nanda, B. Tedbirt, C. Bodemer, M. C. Bolling, M. El Hachem, M. Nikolić, E. Benton, M. Caproni, D. De, D. Didona, K. Drenovska, M. Goebeler, M. Hertl, B. Horváth, M. Kasperkiewicz, D. Kiritsi, M. Larralde, A. V. Marzano, J. Meijer, D. F. Murrell, J. Powell, E. Sprecher, N. S. Chandran, M. M. Tomayko, S. Uzun, N. van Beek, H. Ott, A. Patsatsi, A. Torrelo, A. Welfringer‐Morin, E. Schmidt, P. Joly   +31 more
wiley   +1 more source