Results 11 to 20 of about 25,949 (100)
Melatonin and (−)-Epigallocatechin-3-Gallate: Partners in Fighting Cancer [PDF]
Cells, 2019 We have demonstrated previously that melatonin attenuates hepatotoxicity triggered by high doses of (−)-epigallocatechin-3-gallate (EGCG) in mice. The current work investigated the influence of melatonin on the oncostatic activity of EGCG in two cancer cell lines, wherein melatonin induced an opposite response of p21.
Lingyun Zhang +7 more
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Reactive Carbonyl Species Scavenger: Epigallocatechin-3-Gallate
FoodsEpigallocatechin-3-gallate (EGCG), a prominent polyphenol found abundantly in tea, has garnered significant attention for its potential in preventing and ameliorating a wide range of diseases. Its remarkable antioxidant properties and ability to capture reactive carbonyl species make it a key player among tea’s polyphenolic components.
Haiying Luo, Juanying Ou, Junqing Huang
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Epigallocatechin-3-gallate ameliorates insulin resistance in hepatocytes
Molecular Medicine Reports, 2017 Hyperglycemia is a typical pathogenic factor in a series of complications among patients with type II diabetes. Epigallocatechin-3-gallate (EGCG) is the major polyphenol extracted from green tea and is reported to be an antioxidant. The aim of the present study was to examine the effect of EGCG on insulin resistance in human HepG2 cells pretreated with
Shan-Bo, Ma +8 more
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Epigallocatechin-3-Gallate Reduces Fat Accumulation in Caenorhabditis elegans [PDF]
Preventive Nutrition and Food Science, 2018 Epigallocatechin gallate (EGCG) is a polyphenol that is abundant in green tea. It has been reported that consumption of EGCG can contribute to weight loss, however, the underlying mechanism is not fully understood. To determine how EGCG reduces body fat, an organism model Caenorhabditis elegans was used, which is a useful animal model system in ...
Liu, Jinning +4 more
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Interactions of (−)-epigallocatechin-3-gallate with model lipid membranes
Biochimica et Biophysica Acta (BBA) - Biomembranes, 2022 (-)-Epigallocatechin-3-gallate (EGCG) is a flavonoid known for its good antioxidant potential and health benefits. It is one of the most intriguing flavonoids, especially because of its specific interactions with model lipid membranes. It was noticed that EGCG might form EGCG rich domains/rafts at certain compositions of lipid membranes.
Šturm, Luka +6 more
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Anticancer effects and molecular mechanisms of epigallocatechin-3-gallate
Integrative Medicine Research, 2014 Epigallocatechin-3-gallate (EGCG) is a type of catechin found in green tea. EGCG exhibits a variety of activities, including anti-inflammatory, antidiabetes, antiobesity, and antitumor. In this review, we focus on the antitumor effects of EGCG. EGCG inhibits carcinogen activity, tumorigenesis, proliferation, and angiogenesis, and induces cell death ...
Kyoung-jin Min, Taeg Kyu Kwon
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Epigallocatechin‐3‐gallate protects motor neurons and regulates glutamate level [PDF]
FEBS Letters, 2010 Epigallocatechin‐3‐gallate (EGCG) is a major component of green tea polyphenols which displays potential properties of anticancer and neuroprotection. Here we show that protection of motor neuron by EGCG is associated with regulating glutamate level in organotypic culture of rat spinal cord.
Yu, Jixu +7 more
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Binding of epigallocatechin‐3‐gallate to transthyretin modulates its amyloidogenicity [PDF]
FEBS Letters, 2009 MINT‐7294529: TTR (uniprotkb:P02766) and TTR (uniprotkb:P02766) bind (MI:0407) by comigration in non‐denaturing gel electrophoresis (MI:0404)
Ferreira, Nelson +7 more
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Administration of epigallocatechin-3-gallate for microdermabrasion
Vestnik dermatologii i venerologii, 2010 Rationale of the study As previously demonstrated, epigallocatechin-3-gallate (EGCG) accelerates the formation of the collagenous matrix and at the same time prevents any extraordinary collagen synthesis in the course of wound healing. In addition, EGCG is one of the most potent antioxidants and can inhibit cyclooxygenase-2, which in general lays the ...
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Epigallocatechin-3-gallate counters cisplatin toxicity of rat testes
Pharmaceutical Biology, 2017 Epigallocatechin-3-gallate (EG), the main active flavonoid in green tea, has well-known anti-inflammatory, antioxidant, and anti-apoptotic activities.The EG protection against testicular injury induced by cisplatin was studied in Sprague-Dawley rats.Cisplatin (10 mg/kg, i.p) was given as a single injection to rats.
Amr A. Fouad +4 more
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