Results 41 to 50 of about 13,289,951 (302)

Targeting a transcription factor NF-κB by green tea catechins using in silico and in vitro studies in pancreatic cancer

Frontiers in Nutrition, 2023
Pancreatic cancer remains a lethal disease and a major public health problem globally. Nuclear factor-kappa B (NF-κB) has been identified as a therapeutic target in several cancers and plays an important role in inflammatory responses.
Mohd Suhail, Mohd Suhail, Mohd Rehan, Mohd Rehan, Mohammad Tarique, Shams Tabrez, Shams Tabrez, Amjad Husain, Torki A. Zughaibi, Torki A. Zughaibi   +9 more
doaj   +1 more source

Antitumor activity of the tea polyphenol epigallocatechin-3-gallate encapsulated in targeted vesicles after intravenous administration

, 2013
The therapeutic potential of epigallocatechin gallate, a green tea polyphenol with anti-cancer properties, is limited by its inability to specifically reach tumors following intravenous administration.
McConnell, G., Dufès, C., Dufès, Christine, Lemarié, Fanny, Amor, R., Chang, Chun Wai, Norris, G., Tetley, L., Tetley, Laurence, Blatchford, David, Lemarié, F., Chang, C.W., Norris, Greg, McConnell, Gail, Amor, Rumelo, Blatchford, D.R.   +15 more
core   +1 more source

Computational DNA binding studies of (–)-epigallocatechin-3-gallate [PDF]

Journal of Biomolecular Structure and Dynamics, 2017
The catechin family of molecules that are present in the leaves of green tea has been under investigation since the antioxidant and anti-inflammatory properties of tea were discovered. Among multiple proposed therapeutic targets of these molecules, the direct interaction with nucleic acids has been proposed and experimentally observed but without clear
Rodrigo Galindo-Murillo, Thomas E. Cheatham   +1 more
openaire   +2 more sources

Effects of Infusion and Storage on Antioxidant Activity and Total Phenolic Content of Black Tea

Applied Sciences, 2020
This study determined antioxidant activity in terms of the 1,1-Diphenyl-2-picrylhydrazyl (DPPH) scavenging ability and total phenolic content of black tea under different infusion and storage conditions.
Min-Yun Chang, Yin-Yi Lin, Yu-Chia Chang, Wen-Ying Huang, Wen-Shin Lin, Cheng-You Chen, Shu-Ling Huang, Yung-Sheng Lin   +7 more
doaj   +1 more source

Epigallocatechin gallate suppresses peritoneal fibrosis in mice. [PDF]

, 2012
Long-term peritoneal dialysis (PD) leads to histological changes in the peritoneal membrane. Angiogenesis and inflammation caused by glucose degradation products (GDPs) play crucial roles in peritoneal fibrosis. One such GDP is methylglyoxal (MGO), which
Furusu, Akira, Mineaki Kitamura, Takehiko Koji, Koji, Takehiko, Obata, Yoko, Kitamura, Mineaki, Nishino, Tomoya, Hishikawa, Yoshitaka, Kohno, Shigeru, Yoshitaka Hishikawa, Shigeru Kohno, Tomoya Nishino, Akira Furusu, Yoko Obata   +13 more
core   +1 more source

Interactions of (−)-epigallocatechin-3-gallate with model lipid membranes

Biochimica et Biophysica Acta (BBA) - Biomembranes, 2022
(-)-Epigallocatechin-3-gallate (EGCG) is a flavonoid known for its good antioxidant potential and health benefits. It is one of the most intriguing flavonoids, especially because of its specific interactions with model lipid membranes. It was noticed that EGCG might form EGCG rich domains/rafts at certain compositions of lipid membranes.
Šturm, Luka, Prislan, Iztok, González-Ortega, Rodrigo, Mrak, Polona, Snoj, Tina, Anderluh, Gregor, Poklar Ulrih, Nataša   +6 more
openaire   +3 more sources

Study on application of natural medicine epigallocatechin gallate for primary enamel caries remineralization

口腔疾病防治, 2017
Objective This in vitro study aimed to investigate the remineralization effect of the natural medicine epigallocatechin gallate on artificial enamel caries in primary human teeth.
ZHULIDEZI Tuoliebieke, LIANG Qiujuan, ZHOU Jing, WU Peiling   +3 more
doaj   +1 more source

Assessment Synergistic Effects of Integrated Therapy with Epigallocatechin-3-Gallate (EGCG) & Arsenic Trioxide and Irradiation on Breast Cancer Cell Line

Iranian Journal of Public Health, 2020
Background: Breast cancer is the most common invasive malignancy among women in the world. The current breast cancer therapies pose significant clinical challenges. Low-dose chemotherapy represents a new strategy to treat solid tumors in combination with
Vahid CHANGIZI, Samayeh AZARIASL, Elahe MOTEVASELI, Saeedeh JAFARI NODOOSHAN   +3 more
doaj   +1 more source

Antiviral Effects of Green Tea EGCG and Its Potential Application against COVID-19

Molecules, 2021
(–)-Epigallocatechin-3-O-gallate (EGCG), the most abundant component of catechins in tea (Camellia sinensis (L.) O. Kuntze), plays a role against viruses through inhibiting virus invasiveness, restraining gene expression and replication.
Ying-Qi Wang, Qing-Sheng Li, Xin-Qiang Zheng, Jian-Liang Lu, Yue-Rong Liang   +4 more
doaj   +1 more source

Effects of Epigallocatechin-3-Gallate on Autophagic Lipolysis in Adipocytes [PDF]

Nutrients, 2017
Previous studies demonstrated effects of green tea on weight loss; however, green tea-induced modulation of adipocyte function is not fully understood. Here, we investigated effects of the major green tea phytochemical, epigallocatechin-3-gallate (EGCG) on triglyceride contents, lipolysis, mitochondrial function, and autophagy, in adipocytes ...
Sang-Nam Kim, Hyun-Jung Kwon, Seun Akindehin, Hyun Jeong, Yun-Hee Lee   +4 more
openaire   +2 more sources