Results 51 to 60 of about 13,289,951 (302)
Beneficial effects of green tea on age related diseases
Frontiers in Bioscience-Scholar, 2020 Green tea (Camellia sinensis, Theaceace), has been extensively studied for its putative effects in prevention of age related diseases. Here, we discuss the increasing evidence that consumption of green tea has preventative effects in obesity ...
Juan Chen +9 more
doaj +1 more source
Angewandte Chemie, EarlyView.A coumarin‐based dual‐emission fluorophore was designed to visualize the maturation of protein liquid droplets. Upon covalent conjugation to droplet‐forming proteins, ratiometric fluorescence imaging allowed real time monitoring of droplet maturation. This probe is applicable to the analysis of droplet formation and maturation mechanisms, as well as to
Tomoya Yamamoto +6 more
wiley +2 more sources
Synthesis and Biological Testing of Novel Glucosylated Epigallocatechin Gallate (EGCG) Derivatives
Molecules, 2016 Epigallocatechin gallate (EGCG) is the most abundant component of green tea catechins and has strong physiological activities. In this study, two novel EGCG glycosides (EGCG-G1 and EGCG-G2) were chemoselectively synthesized by a chemical modification ...
Xin Zhang +7 more
doaj +1 more source
QBP1 Peptide as a Potential Anti‐Amyloidogenic Therapy for Type 2 Diabetes: An In Vitro Study
Advanced Science, EarlyView.The anti‐amyloidogenic peptide QBP1 effectively halts human islet amyloid polypeptide (hIAPP) aggregation, preventing the formation of toxic β‐structured intermediates. Through a combination of biophysical assays, molecular dynamics, and cell‐based studies, QBP1 is shown to preserve β‐cell viability and metabolic homeostasis, positioning it as a ...
María M. Tejero‐Ojeda +8 more
wiley +1 more source
Dipeptidyl Peptidase‐4 Is a Target Protein of Epigallocatechin‐3‐Gallate [PDF]
BioMed Research International, 2020 Epigallocatechin‐3‐gallate (EGCG), a major active ingredient in green tea, has various health benefits. It affects glucose metabolism, but the mechanism is not well understood. This study aimed to identify targets of EGCG related to glucose metabolism. The core fragment of EGCG is a flavonoid.
Huimin Hou +4 more
openaire +2 more sources
HeliyonLeea asiatica (L.) Ridsdale has been used by different ethnic communities to manage diseased conditions that can be traced to oxidative stress and cellular inflammations but scientific evidences to support the claim are scanty.
Khem Raj Joshi +9 more
doaj +1 more source
Three New Oxidation Products Produced from Epigallocatechin-3--gallate and Epicatechin-3--gallate
Natural Product Communications, 2016 During chemical studies on uncharacterized black tea polyphenols, the enzymatic oxidation of a mixture of epigallocatechin-3- O -gallate ( 1 ) and epicatechin-3- O -gallate ( 2 ) was examined, and three new dimeric products together with six known ...
Yan Li +3 more
doaj +1 more source
, 2011 Orescent probe propidium iodide was used to visualize dead cells. Compared to control (A) or to 5 μg/ml (B) and 10 μg/ml (C) of EGCG, we observed that 20 μg/ml (D) of EGCG induced a significant (p < 0.01) increase in the dead cell number (E).Copyright ...
Myriam Polette (58028) +8 more
core +1 more source
Selective Inhibition of Integrin β3 Topology Provides a Safer Antithrombotic Strategy
Advanced Science, EarlyView.Current integrin αIIbβ3 inhibitors effectively reduce thrombosis but also increase bleeding risk. During thrombosis, high shear blood flow can directly activate the integrin αIIbβ3 via a distinct topological change in the β3 transmembrane domain, independent of hemostatic platelet signaling.
Joonha Lee +11 more
wiley +1 more source
Fructooligosaccharides Increase in Plasma Concentration of ()-Epigallocatechin-3-Gallate in Rats
, 2021 (−)-Epigallocatechin-3-gallate (EGCG) undergoes auto-oxidation at physiological pH and therefore may be poorly absorbed in the intestine. Fructooligosaccharides (FOS), comprising a group of 1-kestose, nystose, and 1F-β fructofuranosyl-nystose, are ...
Tomonori Unno +13 more
core +1 more source