Results 71 to 80 of about 13,289,951 (302)

Heat Shock Protein 90: From Molecular Chaperone Function to Therapeutic Targeting in Malignancies

open access: yesAdvanced Science, EarlyView.
In this review, an integrated conceptual framework linking HSP90's molecular chaperone functions to its pathological roles in cancer is proposed. HSP90 serves as a central node that integrates oncogenic signaling, buffers proteotoxic stress, maintains cancer stem cell plasticity, and shapes tumor‐immune interactions, all of which converge to drive ...
Beibei Zhang   +4 more
wiley   +1 more source

Impact of Acute Phase Epigallocatechin-3-gallate Supplementation on Consciousness and S100B Serum Levels in TBI Patients: A Double Blind Randomized Clinical Trial

open access: yesIranian Journal of Neurosurgery, 2017
Background and Aim: Traumatic brain injury is one of the leading causes of mortality and disability in young adults. Epigallocatechin-3-gallate, the antioxidant compound of green tea, has been proposed to have antioxidant and anti-inflammatory properties.
Leila Zareian   +4 more
doaj  

Epigallocatechin-3-gallate (EGCG) inhibits the migratory behavior of tumor bronchial epithelial cells-2

open access: yes, 2011
EGCG for a 18 h migratory period. A significant (p < 0.01) decrease of the migration speed was observed when BZR cells were incubated with increasing concentrations of EGCG, compared with control BZR cells (D).
Myriam Polette (58028)   +8 more
core   +1 more source

An Edible Biohybrid Platform Accomplishes In Situ Fenton‐Mediated Enteral Nanoplastics Aging and Excretion

open access: yesAdvanced Science, EarlyView.
An edible biohybrid platform triggers nanoplastics (NPs) aging and agglomeration by in situ generating hydroxyl radicals within the intestine. The enlarged NPs are unable to penetrate the intestine and are subsequently excreted. Simultaneously, probiotic biofilms reinforce the intestinal barrier.
Su Zhou   +4 more
wiley   +1 more source

Administration of epigallocatechin-3-gallate for microdermabrasion

open access: yesVestnik dermatologii i venerologii, 2010
Rationale of the study As previously demonstrated, epigallocatechin-3-gallate (EGCG) accelerates the formation of the collagenous matrix and at the same time prevents any extraordinary collagen synthesis in the course of wound healing. In addition, EGCG is one of the most potent antioxidants and can inhibit cyclooxygenase-2, which in general lays the ...
openaire   +2 more sources

Gmelinoside I, a New Flavonol Glycoside from

open access: yesNatural Product Communications, 2010
Gmelinoside I ( 1 ), a new flavonol glycoside, was isolated and chemically characterized as 3,5,7,3′,4′,5′-hexahydroxy-3- O -α-D-galactopyranosylflavone from the aerial part of Limonium gmelinii Kuntze (Plumbaginaceae)..
Zhanar A. Kozhamkulova   +5 more
doaj   +1 more source

Effects of epigallocatechin-3-gallate on bovine oocytes matured [PDF]

open access: yesAsian-Australasian Journal of Animal Sciences, 2018
Objective Epigallocatechin-3-gallate (EGCG) is a major ingredient of catechin polyphenols and is considered one of the most promising bioactive compounds in green tea because of its strong antioxidant properties.
Ziqiang Huang   +5 more
doaj   +1 more source

Epigallocatechin-3-Gallate Decreases Plasma and Urinary Levels of p‑Cresol by Modulating Gut Microbiota in Mice

open access: yes, 2022
p-Cresol (PC), a gut bacterial product of tyrosine catabolism, is recognized as a uremic toxin that has negative biological effects. Lowering the plasma PC level by manipulating the gut bacterial composition represents a promising therapeutic strategy in
Masaki Ichitani (11797637)   +1 more
core   +1 more source

A Blood‐Derived Double‐Network Hydrogel with Robust Wet Adhesion for Keratinized Mucosa Regeneration via Neutrophil Phenotype Reprogramming and Mechanophysical Niche Modulation

open access: yesAdvanced Science, EarlyView.
The iPRF‐MA/Alg‐NHS/Lut@EGCG (PGAE) double‐network hydrogel achieves durable wet adhesion in the oral environment. It simultaneously reprograms neutrophils from NETosis to phagocytosis for biofilm clearance, and activates the FAK‐RhoA‐YAP mechanotransduction pathway in gingival fibroblasts to drive extracellular matrix remodeling, thereby promoting ...
Sicong Ren   +9 more
wiley   +1 more source

J-shaped association of dietary catechins intake with the prevalence of osteoarthritis and moderating effect of physical activity: an American population-based cohort study

open access: yesFrontiers in Immunology
BackgroundCatechins are a class of natural compounds with a variety of health benefits, The relationship between catechins and the prevalence of osteoarthritis (OA) is unknown.
Yuesong Fu   +5 more
doaj   +1 more source

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