Results 91 to 100 of about 13,289,951 (302)

The effect of Epigallocatechin-3-gallate in allergic airway inflammation

Rhinology journal, 2014
Background: The variety of beneficial effects of green tea has been reported. Epigallocatechin-3-gallate (EGCG) is a major component of green tea extract. The biological activity of EGCG includes anti-allergic and anti-inflammatory activities.
Yoon Seok, Choi, Chang Hoon, Bae, Si-Youn, Song, Yong-Dae, Kim   +3 more
openaire   +3 more sources

Chemical study of leaves of Chrysophyllum marginatum (Hook. & Arn.) Radlk (Sapotaceae)

Química Nova, 2006
The fractionation of the antioxidant ethyl acetate extract obtained from the dried leaves of Chrysophyllum marginatum afforded six substances identified as: alpha-amirin, gallic acid, myricitrin, quercitrin, (-)-epigallocatechin and (-)-epigallocatechin ...
Viviane Cândida da Silva, Márcia Nasser Lopes, Vanderlan da Silva Bolzani   +2 more
doaj   +1 more source

A Systematic Review on Disease‐Modifying Therapies in Parkinsonian Disorders

Clinical Pharmacology &Therapeutics, EarlyView.
Parkinsonian disorders, including Parkinson's disease, Lewy body dementia, multiple system atrophy, and progressive supranuclear palsy, are progressive neurodegenerative conditions with no treatment options to slow disease progression. This systematic review provides an overview of evidence of disease‐modifying therapies that have been evaluated in ...
Pepijn P.N.M. Eijsvogel, Lars M.G. Smits, Philip H.C. Kremer, Geert Jan Groeneveld   +3 more
wiley   +1 more source

Epigallocatechin-3-gallate ameliorates insulin resistance in hepatocytes

Molecular Medicine Reports, 2017
Hyperglycemia is a typical pathogenic factor in a series of complications among patients with type II diabetes. Epigallocatechin-3-gallate (EGCG) is the major polyphenol extracted from green tea and is reported to be an antioxidant. The aim of the present study was to examine the effect of EGCG on insulin resistance in human HepG2 cells pretreated with
Shan-Bo, Ma, Rui, Zhang, Shan, Miao, Bin, Gao, Yang, Lu, Sen, Hui, Long, Li, Xiao-Peng, Shi, Ai-Dong, Wen   +8 more
openaire   +3 more sources

Y6, an Epigallocatechin Gallate Derivative, Reverses ABCG2-Mediated Mitoxantrone Resistance

Frontiers in Pharmacology, 2019
Multidrug resistance is reported to be related to the transmembrane transportation of chemotherapeutic drugs by adenosine triphosphate-binding cassette (ABC) transporters.
Rui-Qiang Zhao, Rui-Qiang Zhao, Rui-Qiang Zhao, Yan Wen, Yan Wen, Pranav Gupta, Zi-Ning Lei, Chao-Yun Cai, Gang Liang, Dong-Hua Yang, Zhe-Sheng Chen, Yu-An Xie   +11 more
doaj   +1 more source

Epigallocatechin-3-gallate (EGCG) inhibits the migratory behavior of tumor bronchial epithelial cells-6

, 2011
And 7.5 μg/ml (C, F) of EGCG. In presence of EGCG at 5 (B) or 7.5 μg/ml (C), we observed a decrease in the number of cells expressing vimentin. At higher magnification (D, E, F), alterations of the vimentin network were observed: less expression and more
Myriam Polette (58028), Magali Milliot (58025), Christine Terryn (58026), Philippe Birembaut (58029), Jérôme Cutrona (58027), Salma Hazgui (58022), Jean-Marie Zahm (27105), Arnaud Bonnomet (58023), Béatrice Nawrocki-Raby (58024)   +8 more
core   +1 more source

Food phytochemicals, epigallocatechin gallate and myricetin, covalently bind to the active site of the coronavirus main protease in vitro

, 2021
SARS-CoV-2 main protease is a possible target for protection against viral infection. This study examined the inhibitory effect of food phytochemicals on the main protease of SARS-CoV-2 by determining a cleaved product after chromatographic separation ...
Yoji, Kato, Emi, Takaoka, Akari, Higashiyama, Shinichi, Ikushiro, Miyu, Nishikawa   +4 more
core   +1 more source

Hydrogel Adhesives for Gastrointestinal Perforation: Design Principles and Applications

Exploration, EarlyView.
There are few reviews on hydrogel adhesives that comprehensively highlight the design principles, factors affecting adhesion, and applications for gastrointestinal (GI) perforation repair. This review outlines the mainstream design approaches of hydrogel adhesives via covalent and noncovalent molecular interactions, illustrating the underlying adhesive
Yudi Pang, Shuai Tian, Qinyu Han, Yulin Deng, Jiatao Zhang, Enqiang Linghu, Qianqian Chen, Zhimin Wang   +7 more
wiley   +1 more source

A New Vista of Opportunity in Diabetes Management: Natural Product‐Based β‐cell Preservation

Food Chemistry International, EarlyView.
Preserving functional β‐cells via natural products offers promising strategy for diabetes treatment. ABSTRACT A defining characteristic of diabetes is β‐cell failure, in which β‐cells cannot modulate insulin secretion to compensate for escalating insulin resistance, pushing forward disease development.
Yi‐San Lee, Tien‐Fen Kuo, Chun‐Yen Yang, Greta Yang, Wen‐Chin Yang   +4 more
wiley   +1 more source

Anticancer activities of epigallocatechin-3-gallate against cholangiocarcinoma cells

OncoTargets and Therapy, 2016
Epigallocatechin-3-gallate (EGCG) is an antioxidant agent derived from green tea. Because it has chemopreventive and anti-invasive effect against various cancer cells, EGCG can be used to inhibit proliferation and invasion of cholangiocarcinoma (CCA) cells.The anticancer effects of EGCG were studied using human CCA cells (HuCC-T1).
Kwak, Tae Won, Park, Su Bum, Kim, Hyun-Jung, Jeong, Young-IL, Kang, Dae Hwan   +4 more
openaire   +4 more sources