Reactive Carbonyl Species Scavenger: Epigallocatechin-3-Gallate
Epigallocatechin-3-gallate (EGCG), a prominent polyphenol found abundantly in tea, has garnered significant attention for its potential in preventing and ameliorating a wide range of diseases.
Haiying Luo, Juanying Ou, Junqing Huang
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Anticancer effects and molecular mechanisms of epigallocatechin-3-gallate
Epigallocatechin-3-gallate (EGCG) is a type of catechin found in green tea. EGCG exhibits a variety of activities, including anti-inflammatory, antidiabetes, antiobesity, and antitumor. In this review, we focus on the antitumor effects of EGCG.
Kyoung-jin Min, Taeg Kyu Kwon
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Inhibitory Effects of (−)-Epigallocatechin-3-gallate on Esophageal Cancer [PDF]
There is epidemiological evidence showing that drinking green tea can lower the risk of esophageal cancer (EC). The effect is mainly attributed to tea polyphenols and their most abundant component, (−)-epigallocatechin-3-gallate (EGCG).
Liu-Xiang Wang +9 more
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TLC separation of methylated (-)-epigallocatechin-3-gallate [PDF]
Methylated EGCG was separated from the crude extract using Sephadex LH-20 column chromatography with methanol as the mobile phase, and a semi-preparative HPLC method with water-dimethylformamide-methanol-acetic acid (157:40:2:1, v/v/v/v) as the mobile ...
Ryszard Amarowicz +2 more
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Melatonin and (−)-Epigallocatechin-3-Gallate: Partners in Fighting Cancer [PDF]
We have demonstrated previously that melatonin attenuates hepatotoxicity triggered by high doses of (−)-epigallocatechin-3-gallate (EGCG) in mice.
Lingyun Zhang +7 more
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Effects of epigallocatechin-3-gallate combined with ascorbic acid and glycerol on the stability and uric acid-lowering activity of epigallocatechin-3-gallate [PDF]
Context Epigallocatechin-3-gallate (EGCG) is unstable and easily oxidized, which limits its applications. Ascorbic acid (Vc) is a natural antioxidant.
Qianjin Xie +6 more
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(−)-Epigallocatechin-3-gallate Is a Novel Hsp90 Inhibitor [PDF]
(-)-Epigallocatechin-3-gallate (EGCG), a major component of green tea, protects against certain types of cancers, although the mechanism has not yet been determined. It was previously demonstrated that EGCG blocks aryl hydrocarbon receptor (AhR)-mediated transcription induced by the potent carcinogen 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD).
Zhengyu, Yin +2 more
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Antifibrotic properties of epigallocatechin-3-gallate in endometriosis [PDF]
Is epigallocatechin-3-gallate (EGCG) treatment effective in the treatment of fibrosis in endometriosis?EGCG appears to have antifibrotic properties in endometriosis.Histologically, endometriosis is characterized by dense fibrous tissue surrounding the endometrial glands and stroma.
Sachiko, Matsuzaki, Claude, Darcha
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Phytochemical Characterization of an Adaptogenic Preparation from
The phytochemical constituents of a biologically active, standardized, 80% ethanol extract of Rhodiola heterodonta were characterized. The extract was fractionated over a Sephadex LH-20 column to afford two main fractions representing two classes of ...
Mary H. Grace +4 more
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Epigallocatechin-3-gallate and cancer: focus on the role of microRNAs
AbstractMicroRNAs (miRNAs) are a group of small non-coding RNAs that affect gene expression. The role of miRNAs in different types of cancers has been published and it was shown that several miRNAs are inappropriately expressed in different cancers. Among the mechanisms that can cause this lack of proper expression are epigenetics, chromosomal changes,
Chunguang Wang +6 more
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