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Epigallocatechin-3-gallate

Nutrition & Food Science, 2017
Purpose The purpose of the study was to explore the possibility of utilization of epigallocatechin-3-gallate (EGCG) as a novel preservative in cheese. EGCG has strong antioxidant and antimicrobial properties and may be commercially exploited as a natural antioxidant and preservative in cheese like products which are highly susceptible to lipid ...
Deepak Mahajan, Z.F. Bhat, Sunil Kumar
openaire   +1 more source

Antioxidant Nanocomplexes for Delivery of Epigallocatechin-3-gallate

Journal of Agricultural and Food Chemistry, 2016
Modification of chitosan (CS) through grafting with caffeic acid (CA, CA-g-CS) and ferulic acid (FA, FA-g-CS) significantly improved its solubility under neutral and alkaline environments. Spherical and physicochemically stable nanocomplexes assembled from the phenolic acid grafting CS and caseinophosphopeptide (CPP) were obtained with particle size
Bing, Hu   +6 more
openaire   +2 more sources

Attenuation of methotrexate induced hepatotoxicity by epigallocatechin 3-gallate

Drug and Chemical Toxicology, 2022
Methotrexate (MTX) is currently used as first-line therapy for autoimmune diseases like rheumatoid arthritis, psoriasis, and systemic lupus erythematous. However, its use is limited by its hepatotoxic potential. Epigallocatechin-3-gallate (EGCG), an abundant catechin present in tea possesses potent antioxidant activity and effectively ameliorates ...
Ayan Pradhan   +3 more
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Promotion of Neuronal Plasticity by (−)-Epigallocatechin-3-Gallate

Neurochemical Research, 2007
The consumption of (-)-epigallocatechin-3-gallate (EGCG), the major polyphenolic compound found in green tea, has been associated with various neurological benefits including cognitive improvement. The physiological basis for this effect is unknown. In this study, we used synaptic transmission between the CA3 and CA1 regions (Schaffer collateral) of ...
Wen, Xie   +3 more
openaire   +2 more sources

Effect Of epigallocatechin-3-gallate on the pharmacokinetics of amlodipine in rats

Xenobiotica, 2018
This study investigates the effect of epigallocatechin-3-gallate (EGCG), a major ingredient of green tea, on the pharmacokinetics of amlodipine in rats. The pharmacokinetics of orally administered amlodipine (1 mg/kg) with or without EGCG pretreatment (30 mg/kg/day for 10 days) were investigated.
Xiuyuan, Han   +5 more
openaire   +2 more sources

Effects of folate cycle disruption by the green tea polyphenol epigallocatechin-3-gallate [PDF]

open access: yesInternational Journal of Biochemistry and Cell Biology, 2007
©. This is the Accepted manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/ This document is the Accepted version of a Published Work that appeared in final form in The International ...
Juan Cabezas-Herrera   +1 more
exaly   +2 more sources

(−)-Epigallocatechin-3-gallate Inhibits Fibrillogenesis of Chicken Cystatin

Journal of Agricultural and Food Chemistry, 2015
Previous studies have reported that (-)-epigallocatechin-3-gallate (EGCG), the most abundant flavonoid in green tea, can bind to unfolded native polypeptides and prevent conversion to amyloid fibrils. To elucidate whether this antifibril activity is specific to disease-related target proteins or is more generic, we investigated the ability of EGCG to ...
Na, Wang   +13 more
openaire   +2 more sources

Epigallocatechin-3-Gallate, a Promising Molecule for Parkinson's Disease?

Rejuvenation Research, 2015
Parkinson's disease (PD) is the second most common neurodegenerative disease, and it is characterized by the loss of the neurotransmitter dopamine and neuronal degeneration in the substantia nigra pars compacta. Thus far, current therapeutic strategies have failed to address neuronal degeneration.
Renaud Justine   +4 more
openaire   +4 more sources

Chemoprevention of fibroid tumors by [−]-epigallocatechin-3-gallate in quail

Nutrition Research, 2008
Spontaneous leiomyomas of the oviduct are common tumors of the Japanese quail (Coturnix coturnix japonica), and fibroid tumors in the laying hen are similar to human fibroid tumors with respect to estrogen and progesterone receptors. This makes the quail a good animal model for screening potential agents for that aid in the prevention and treatment of ...
Ibrahim H, Ozercan   +6 more
openaire   +2 more sources

Epigallocatechin-3-gallate(EGCG): Mechanisms and the Combined Applications

Combinatorial Chemistry & High Throughput Screening, 2018
EGCG is the most important pharmacological component in tea. Researches have confirmed its effects, including anti-tumor, anti-inflammation, anti-aging, anti-obesity, anti-diabetic, cardiovascular disease prevention and protection, immunoregulation and neuroprotection. Paradoxically, the clinical application of EGCG is very rare.
Xuekun, Song   +3 more
openaire   +2 more sources

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