Results 61 to 70 of about 14,428 (154)

Parental epigenetic age acceleration and risk of adverse birth outcomes: the Norwegian mother, father and child cohort study

BMC Medicine
Background Few studies have examined associations between maternal epigenetic age acceleration and adverse birth outcomes, and none have investigated paternal epigenetic age acceleration.
Maria C. Magnus, Yunsung Lee, Ellen Ø. Carlsen, Lise A. Arge, Astanand Jugessur, Liv G. Kvalvik, Nils-Halvdan Morken, Cecilia H. Ramlau-Hansen, Mikko Myrskylä, Per Magnus, Siri E. Håberg   +10 more
doaj   +1 more source

Genetic association of the gut microbiota with epigenetic clocks mediated by inflammatory cytokines: a Mendelian randomization analysis

Frontiers in Immunology
BackgroundA new aging biomarker epigenetic clock has been developed. There exists a close link between aging and gut microbiota, which may be mediated by inflammatory cytokines.
Siyu Tian, Xingyu Liao, Siqi Chen, Yu Wu, Min Chen   +4 more
doaj   +1 more source

Epigenetic age acceleration and risk of aortic valve stenosis: a bidirectional Mendelian randomization study

Clinical Epigenetics
Background Aortic valve stenosis (AVS) is the most prevalent cardiac valve lesion in developed countries, and pathogenesis is closely related to aging.
Wanqian Pan, Qi Huang, Le Zhou, Jia Lin, Xiaojiao Du, Xiaodong Qian, Tingbo Jiang, Weixiang Chen   +7 more
doaj   +1 more source

A Cost-Effective Saliva-Based Human Epigenetic Clock Using 10 CpG Sites Identified with the Illumina EPIC 850k Array

DNA
Background/Objectives: DNA methylation profiles have emerged as robust biomarkers of ageing, leading to the development of “epigenetic clocks” that estimate biological age. Most established clocks (e.g., Horvath’s 353-CpG pan-tissue clock and Hannum’s 71-
Christopher Collins, James Brown, Henry C. Chung   +2 more
doaj   +1 more source

Epigenetic events influencing the biological clock: Panacea for neurodegeneration

Heliyon
The human biological clock is the 24-h internal molecular network of circadian genes in synchronization with other cells in response to external stimuli.
Indrani Paramasivan Latha Laxmi, Ramasamy Tamizhselvi   +1 more
doaj   +1 more source

Epigenetic aging acceleration among World Trade Center-exposed community members

Scientific Reports
Aging is a complex biological process, and some individuals are aging faster or slower than expected. This phenomenon of aging acceleration occurs when biological age exceeds chronological age and can be assessed by epigenetic clock estimation.
Stephanie Tuminello, Yibeltal Arega Ashebir, Chanel Schroff, Sitharam Ramaswami, Nedim Durmus, Yu Chen, Matija Snuderl, Yongzhao Shao, Joan Reibman, Alan A. Arslan   +9 more
doaj   +1 more source

Epigenetic clock: a promising mirror of ageing [PDF]

The Lancet Healthy Longevity, 2021
Zuyun Liu, Yimin Zhu
openaire   +3 more sources

Consistent cord blood DNA methylation signatures of gestational age between South Asian and white European cohorts

Clinical Epigenetics
Background Epigenetic modifications, particularly DNA methylation (DNAm) in cord blood, are an important biological marker of how external exposures during gestation can influence the in-utero environment and subsequent offspring development. Despite the
Wei Q. Deng, Marie Pigeyre, Sandi M. Azab, Samantha L. Wilson, Natalie Campbell, Nathan Cawte, Katherine M. Morrison, Stephanie A. Atkinson, Padmaja Subbarao, Stuart E. Turvey, Theo J. Moraes, Piush Mandhane, Meghan B. Azad, Elinor Simons, Guillaume Pare, Sonia S. Anand   +15 more
doaj   +1 more source

A Review of the Epigenetic Clock: Emerging Biomarkers for Asthma and Allergic Disease. [PDF]

Genes (Basel), 2023
Vasileva D, Greenwood CMT, Daley D.
europepmc   +1 more source

Region-based epigenetic clock design improves RRBS-based age prediction. [PDF]

Aging Cell, 2023
Simpson DJ, Zhao Q, Olova NN, Dabrowski J, Xie X, Latorre-Crespo E, Chandra T, Chandra T.   +7 more
europepmc   +2 more sources