Results 71 to 80 of about 35,251 (213)

Epigenetic/circadian clocks and PCOS

open access: yesHuman Reproduction
Abstract Polycystic ovary syndrome (PCOS) affects 6–20% of reproductive-aged women. It is associated with increased risks of metabolic syndrome, Type 2 diabetes, cardiovascular diseases, mood disorders, endometrial cancer and non-alcoholic fatty liver disease.
Camille Vatier, Sophie Christin-Maitre
openaire   +3 more sources

Ultrastructural analysis of changes in neurons of the mouse internal anal sphincter during ageing [PDF]

open access: yes, 2013
Gastrointestinal disorders, including chronic constipation, faecal impaction and incontinence, are a major cause of morbidity in the ...
Colyer, Frances   +5 more
core  

Accelerated epigenetic aging in Werner syndrome. [PDF]

open access: yes, 2017
Individuals suffering from Werner syndrome (WS) exhibit many clinical signs of accelerated aging. While the underlying constitutional mutation leads to accelerated rates of DNA damage, it is not yet known whether WS is also associated with an increased ...
Flunkert, Julia   +5 more
core   +1 more source

Longitudinal study of DNA methylation and epigenetic clocks prior to and following test-confirmed COVID-19 and mRNA vaccination [PDF]

open access: green, 2021
Alina P.S. Pang   +12 more
openalex   +1 more source

Circadian Regulation of Immunity Through Epigenetic Mechanisms

open access: yesFrontiers in Cellular and Infection Microbiology, 2020
The circadian clock orchestrates daily rhythms in many physiological, behavioral and molecular processes, providing means to anticipate, and adapt to environmental changes.
Ricardo Orozco-Solis   +1 more
doaj   +1 more source

The association of epigenetic clocks in brain tissue with brain pathologies and common aging phenotypes

open access: yesNeurobiology of Disease, 2021
Epigenetic clocks are calculated by combining DNA methylation states across select CpG sites to estimate biologic age, and have been noted as the most successful markers of biologic aging to date.
Francine Grodstein   +10 more
doaj   +1 more source

Vascular Growth in the Fetal Lung [PDF]

open access: yes, 2011
The structure of the lung is truly remarkable. It is primarily composed of three branched tubular networks (the airway, pulmonary artery and vein, bronchial artery and vein) which supply blood and air to the site of gas exchange and which maintain ...
Land, Stephen
core   +4 more sources

Susceptibility to hormone-mediated cancer is reflected by different tick rates of the epithelial and general epigenetic clock

open access: yesGenome Biology, 2022
Background A variety of epigenetic clocks utilizing DNA methylation changes have been developed; these clocks are either tissue-independent or designed to predict chronological age based on blood or saliva samples.
James E. Barrett   +14 more
doaj   +1 more source

Exaggerated CpH methylation in the autism-affected brain. [PDF]

open access: yes, 2017
BackgroundThe etiology of autism, a complex, heritable, neurodevelopmental disorder, remains largely unexplained. Given the unexplained risk and recent evidence supporting a role for epigenetic mechanisms in the development of autism, we explored the ...
Arking, Dan E   +4 more
core   +1 more source

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