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Epigenetic modifications and human disease

Nature Biotechnology, 2010
Epigenetics is one of the most rapidly expanding fields in biology. The recent characterization of a human DNA methylome at single nucleotide resolution, the discovery of the CpG island shores, the finding of new histone variants and modifications, and the unveiling of genome-wide nucleosome positioning maps highlight the accelerating speed of ...
Anna, Portela, Manel, Esteller
openaire   +2 more sources

Epigenetic Modifications and Modulators in Prostate Cancer

Critical Reviews™ in Oncogenesis, 2017
Prostate cancer (PCa) is one of the most common malignancies in men. Its clinical behavior ranges from indolent to aggressive. The clinical and morphological methods and features currently adopted show a low predictive value concerning the definition of its level of aggressiveness.
Cimadamore A.   +8 more
openaire   +3 more sources

Assessment of DNA Epigenetic Modifications

Chemical Research in Toxicology, 2019
DNA molecules utilize adenine, thymine, cytosine, and guanine for coding genetic information. In addition to these four canonical nucleobases, DNA molecules also contain a variety of modified nucleobases that can control and regulate gene expression and chromosome structure.
openaire   +2 more sources

Cancer epigenetics in clinical practice

Ca-A Cancer Journal for Clinicians, 2023
Veronica Davalos, Manel Esteller
exaly  

Interplay Among Metabolism, Epigenetic Modifications, and Gene Expression in Cancer

Frontiers in Cell and Developmental Biology, 2021
Miaomiao Huo
exaly  

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