Results 71 to 80 of about 2,264,000 (323)
Epigenetic regulation of angiogenesis and its therapeutics
Genomics & InformaticsAngiogenesis, the formation of new blood vessels from preexisting ones, is essential for normal development, wound healing, and tissue repair. However, dysregulated angiogenesis is implicated in various pathological conditions, including cancer, diabetic
Dong Kyu Choi
doaj +1 more source
Potential epigenetic molecular regulatory networks in ocular neovascularization
Frontiers in Genetics, 2022 Neovascularization is one of the many manifestations of ocular diseases, including corneal injury and vascular diseases of the retina and choroid. Although anti-VEGF drugs have been used to effectively treat neovascularization, long-term use of anti ...
Qiang Hu +5 more
doaj +1 more source
m6a RNA methylation: the implications for health and disease [PDF]
, 2014 The recent resurgence of interest in m6a has been spurred by some intriguing findings detailing the effects and dynamics of this epigenetic modification.
McGuinness, D., Mcguinness, D.H.
core +1 more source
A Novel Loop: Mutual Regulation Between Epigenetic Modification and the Circadian Clock
Frontiers in Plant Science, 2019 In response to periodic environmental fluctuations generated by the rotation of the earth, nearly all organisms have evolved an intrinsic timekeeper, the circadian clock, which can maintain approximate 24-h rhythmic oscillations in biological processes ...
Shenxiu Du +3 more
semanticscholar +1 more source
Epigenetic modifications in rheumatoid arthritis [PDF]
Arthritis Research & Therapy, 2008 Over the last decades, genetic factors for rheumatoid diseases like the HLA haplotypes have been studied extensively. However, during the past years of research, it has become more and more evident that the influence of epigenetic processes on the development of rheumatic diseases is probably as strong as the genetic background of a patient. Epigenetic
Strietholt, Simon +4 more
openaire +2 more sources
Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Latent consequences of early-life lead (Pb) exposure and the future: Addressing the Pb crisis [PDF]
, 2018 Background. The lead (Pb) exposure crisis in Flint, Michigan has passed from well-publicized event to a footnote, while its biological and social impact will linger for lifetimes.
Bayon, Baindu L. +3 more
core +2 more sources
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Epigenetic alterations in female urogenital organs cancer: Premise, properties, and perspectives
Scientific African, 2020 Cancer is a sickness, initiated and driven via accumulation and interaction of genetic and epigenetic modification of genes involved in regulation of cell communication, signaling and growth division.
Abdelkareem A. Ahmed +1 more
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Role of epigenetic modification in interferon treatment of hepatitis B virus infection
Frontiers in Immunology, 2022 Human hepatitis B virus (HBV) is a small, enveloped DNA virus that causes acute and chronic hepatitis. Chronic hepatitis B (CHB) is associated with hepatocellular carcinoma pathogenesis.
Zhijing Yang +17 more
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