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New Generation of Clinical Epigenetics Analysis and Diagnosis for Precision Medicine. [PDF]

open access: yesDiagnostics (Basel)
Following the application of epigenetic and epigenomics research into tumor diseases, cardiovascular disease, diabetes, hereditary diseases, and rare diseases, in vitro diagnostics (IVD) epigenetic and epigenomics are increasingly employed for those ...
Song P, Li B.
europepmc   +2 more sources

The social brain meets the reactive genome: neuroscience, epigenetics and the new social biology

open access: yesFrontiers in Human Neuroscience, 2014
The rise of molecular epigenetics over the last few years promises to bring the discourse about the sociality and susceptibility to environmental influences of the brain to an entirely new level.
Maurizio Meloni
exaly   +3 more sources

Molecular Epigenetics in the Management of Ovarian Cancer: Are We Investigating a Rational Clinical Promise?

open access: yesFrontiers in Oncology, 2014
Epigenetics is essentially a phenotypical change in gene expression without any alteration of the DNA sequence; the emergence of epigenetics in cancer research and mainstream oncology is fueling new hope.
Ha eNguyen   +3 more
exaly   +3 more sources

Epigenetic regulation in metabolic diseases: mechanisms and advances in clinical study

open access: yesSignal Transduction and Targeted Therapy, 2023
Epigenetics regulates gene expression and has been confirmed to play a critical role in a variety of metabolic diseases, such as diabetes, obesity, non-alcoholic fatty liver disease (NAFLD), osteoporosis, gout, hyperthyroidism, hypothyroidism and others.
Yan-Lin Wu   +9 more
doaj   +1 more source

How Epigenetics Contributes to the Understanding of Human Development

open access: yesESPOCH Congresses, 2021
Introduction: Epigenetics, which studies the phenotypic expression of certain characteristics in relation to the interaction with the environment, specifically of the primary DNA (deoxyribonucleic acid) sequence and that does not modulate the genetic ...
Iván Enrique Naranjo Logroño   +3 more
doaj   +1 more source

EPIGENETICS

open access: yesRevista de la Sociedad Argentina de Diabetes, 2020
It is now accepted that the product of pregnancy in mothers who have been exposed to malnutrition, obesity or gestational diabetes (GD) has an increased risk of developing chronic diseases throughout their lives.
Cristina Faingold
doaj   +3 more sources

The Crosstalk of Epigenetics and Metabolism in Herpesvirus Infection

open access: yesViruses, 2020
Epigenetics is a versatile player in manipulating viral infection and a potential therapeutic target for the treatment of viral-induced diseases. Both epigenetics and metabolism are crucial in establishing a highly specific transcriptional network, which
Yonggang Pei, Erle S. Robertson
doaj   +1 more source

Constitutively bound CTCF sites maintain 3D chromatin architecture and long-range epigenetically regulated domains

open access: yesNature Communications, 2020
The architectural protein CTCF is a mediator of chromatin conformation, but how CTCF binding to DNA is regulated remains poorly understood. Here the authors find that there is a shared subset of CTCF-bound sites resistant to protein depletion in ...
Amanda Khoury   +13 more
doaj   +1 more source

Epigenetics and Cancer: A Comprehensive Review

open access: yesAsian Pacific Journal of Cancer Biology, 2023
Cancer is a disease with extraordinary clinical significance, with much of medical research being devoted to it. Innumerable factors are relevant in fully understanding cancer but the epigenetic aspect stands out.
Ayush Pathak   +2 more
doaj   +1 more source

Epigenetics for the 21st-Century Biology Student

open access: yesJournal of Microbiology & Biology Education, 2019
Epigenetics, a rapidly emerging biological science, investigates changes in gene expression without any change to the primary DNA sequence. Epigenetics plays an important role in diverse areas, including nutritional sciences, psychology, and ...
Jonghoon Kang   +3 more
doaj   +1 more source

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