Results 1 to 10 of about 458,162 (417)
The social brain meets the reactive genome: neuroscience, epigenetics and the new social biology [PDF]
Frontiers in Human Neuroscience, 2014 The rise of molecular epigenetics over the last few years promises to bring the discourse about the sociality and susceptibility to environmental influences of the brain to an entirely new level.
Maurizio Meloni
exaly +7 more sources
Frontiers in Oncology, 2014 Epigenetics is essentially a phenotypical change in gene expression without any alteration of the DNA sequence; the emergence of epigenetics in cancer research and mainstream oncology is fueling new hope.
Ha eNguyen +3 more
exaly +3 more sources
Proceedings of the National Academy of Sciences, 2013 In higher eukaryotic organisms epigenetic modifications are crucial for proper chromatin folding and thereby proper regulation of gene expression. Epigenetics include DNA methylation, histone modifications, and microRNAs. First described in tumors, the involvement of aberrant epigenetic modifications has been reported also in other diseases, i.e ...
Steffen Gay, Michel Neidhart
openaire +3 more sources
Introduction to Epigenetics [PDF]
, 2021 Learning Materials in ...
Paro, Renato +3 more
openaire +3 more sources
Epigenetic regulation in metabolic diseases: mechanisms and advances in clinical study
Signal Transduction and Targeted Therapy, 2023 Epigenetics regulates gene expression and has been confirmed to play a critical role in a variety of metabolic diseases, such as diabetes, obesity, non-alcoholic fatty liver disease (NAFLD), osteoporosis, gout, hyperthyroidism, hypothyroidism and others.
Yan-Lin Wu +9 more
doaj +1 more source
Genes, 2019 This special issue of Genes demonstrates clearly that research in epigenetics has proceeded at a very rapid pace in the last decade [...]
Christoph Grunau +3 more
openaire +6 more sources
Current Genomics, 2015 The best-known phenomenon exemplifying epigenetic drift (the alteration of epigenetic patterns during aging) is the gradual decrease of global DNA methylation. Aging cells, different tissue types, as well as a variety of human diseases possess their own distinct DNA methylation profiles, although the functional impact of these is not always clear.
Sierra, Marta I. +2 more
openaire +4 more sources
How Epigenetics Contributes to the Understanding of Human Development
ESPOCH Congresses, 2021 Introduction: Epigenetics, which studies the phenotypic expression of certain characteristics in relation to the interaction with the environment, specifically of the primary DNA (deoxyribonucleic acid) sequence and that does not modulate the genetic ...
Iván Enrique Naranjo Logroño +3 more
doaj +1 more source
Epigenetic Metalloenzymes [PDF]
Current Medicinal Chemistry, 2019 Epigenetics controls the expression of genes and is responsible for cellular phenotypes. The fundamental basis of these mechanisms involves in part the post-translational modifications (PTMs) of DNA and proteins, in particular, the nuclear histones. DNA can be methylated or demethylated on cytosine.
Blanquart, Christophe +5 more
openaire +5 more sources