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Genes, 2019 This special issue of Genes demonstrates clearly that research in epigenetics has proceeded at a very rapid pace in the last decade [...]
Christoph Grunau +3 more
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Genetics and Epigenetics in Asthma
International Journal of Molecular Sciences, 2021 Asthma is one of the most common respiratory disease that affects both children and adults worldwide, with diverse phenotypes and underlying pathogenetic mechanisms poorly understood. As technology in genome sequencing progressed, scientific efforts were
P. Ntontsi +4 more
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Nature Communications, 2020 The architectural protein CTCF is a mediator of chromatin conformation, but how CTCF binding to DNA is regulated remains poorly understood. Here the authors find that there is a shared subset of CTCF-bound sites resistant to protein depletion in ...
Amanda Khoury +13 more
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Epigenetics and Cancer: A Comprehensive Review
Asian Pacific Journal of Cancer Biology, 2023 Cancer is a disease with extraordinary clinical significance, with much of medical research being devoted to it. Innumerable factors are relevant in fully understanding cancer but the epigenetic aspect stands out.
Ayush Pathak +2 more
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NeuroToxicology, 2023 Methylmercury (MeHg) is neurotoxic at high levels and particularly affects the developing brain. One proposed mechanism of MeHg neurotoxicity is alteration of the epigenetic programming. In this review, we summarise the experimental and epidemiological literature on MeHg-associated epigenetic changes.Experimental and epidemiological studies have ...
Cediel-Ulloa, Andrea +3 more
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Ayurveda and Epigenetics [PDF]
Medicina, 2020 Ayurveda is a comprehensive, natural health care system that originated in the ancient Vedic times of India. Epigenetics refers to the external modification of DNA that turns genes on and off, affecting gene expression. This occurs without changes in the basic structure of the DNA. This gene expression can have transgenerational effects.
Hari Sharma, Robert Keith Wallace
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Epigenetics for the 21st-Century Biology Student
Journal of Microbiology & Biology Education, 2019 Epigenetics, a rapidly emerging biological science, investigates changes in gene expression without any change to the primary DNA sequence. Epigenetics plays an important role in diverse areas, including nutritional sciences, psychology, and ...
Jonghoon Kang +3 more
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Carcinogenesis, 2010 Epigenetic mechanisms are essential for normal development and maintenance of tissue-specific gene expression patterns in mammals. Disruption of epigenetic processes can lead to altered gene function and malignant cellular transformation.
Shikhar Sharma, T. Kelly, Peter A. Jones
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American Journal of Lifestyle Medicine, 2018 The field of Epigenetics represents the science which helps us understand the influence life has on genetic function. Research has shown that what we do, what we are exposed to, and the internal and external environments have significant influence on the output of our genes.
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Computational epigenetics [PDF]
Bioinformatics, 2007 Abstract Epigenetic research aims to understand heritable gene regulation that is not directly encoded in the DNA sequence. Epigenetic mechanisms such as DNA methylation and histone modifications modulate the packaging of the DNA in the nucleus and thereby influence gene expression.
Bock, C., Lengauer, T.
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