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Reversible, spatial, and temporal regulation of metabolic reprogramming and epigenetic homeostasis are prominent hallmarks of carcinogenesis. Cancer cells reprogram their metabolism to meet the high bioenergetic and biosynthetic demands for vigorous ...
T. Ge +6 more
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The field of Epigenetics represents the science which helps us understand the influence life has on genetic function. Research has shown that what we do, what we are exposed to, and the internal and external environments have significant influence on the output of our genes.
openaire +2 more sources
The modern versus extended evolutionary synthesis : sketch of an intra-genomic gene's eye view for the evolutionary-genetic underpinning of epigenetic and developmental evolution [PDF]
Studying the phenotypic evolution of organisms in terms of populations of genes and genotypes, the Modern Synthesis (MS) conceptualizes biological evolution in terms of 'inter-organismal' interactions among genes sitting in the different individual ...
Blancke, Stefaan +2 more
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Genetics and Epigenetics in Asthma
Asthma is one of the most common respiratory disease that affects both children and adults worldwide, with diverse phenotypes and underlying pathogenetic mechanisms poorly understood. As technology in genome sequencing progressed, scientific efforts were
P. Ntontsi +4 more
semanticscholar +1 more source
Epigenetics for the 21st-Century Biology Student
Epigenetics, a rapidly emerging biological science, investigates changes in gene expression without any change to the primary DNA sequence. Epigenetics plays an important role in diverse areas, including nutritional sciences, psychology, and ...
Jonghoon Kang +3 more
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Understanding Health Inequalities Through the Lens of Social Epigenetics
Longstanding racial/ethnic inequalities in morbidity and mortality persist in the United States. Although the determinants of health inequalities are complex, social and structural factors produced by inequitable and racialized systems are recognized as ...
Chantel L. Martin +4 more
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Environmental epigenetics [PDF]
Epigenetics investigates heritable changes in gene expression that occur without changes in DNA sequence. Several epigenetic mechanisms, including DNA methylation and histone modifications, can change genome function under exogenous influence. We review current evidence indicating that epigenetic alterations mediate effects caused by exposure to ...
V. Bollati, A. Baccarelli
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Epigenetics of Aging and Aging-Associated Diseases
Aging represents the multifactorial decline in physiological function of every living organism. Over the past decades, several hallmarks of aging have been defined, including epigenetic deregulation.
D. Saul, R. L. Kosinsky
semanticscholar +1 more source
Epigenetic inheritance. Concepts, mechanisms and perspectives [PDF]
Parents' stressful experiences can influence an offspring's vulnerability to many pathological conditions, including psychopathologies, and their effects may even endure for several generations.
Lacal, Irene, Ventura, Rossella
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Ethical implications of epigenetics in the era of personalized medicine
Given the increasing research activity on epigenetics to monitor human diseases and its connection with lifestyle and environmental expositions, the field of epigenetics has attracted a great deal of interest also at the ethical and societal level.
J. Santaló, M. Berdasco
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