Results 21 to 30 of about 495,214 (384)

Crosstalk between metabolic reprogramming and epigenetics in cancer: updates on mechanisms and therapeutic opportunities

open access: yesCancer Communications, 2022
Reversible, spatial, and temporal regulation of metabolic reprogramming and epigenetic homeostasis are prominent hallmarks of carcinogenesis. Cancer cells reprogram their metabolism to meet the high bioenergetic and biosynthetic demands for vigorous ...
T. Ge   +6 more
semanticscholar   +1 more source

Epigenetics [PDF]

open access: yesAmerican Journal of Lifestyle Medicine, 2018
The field of Epigenetics represents the science which helps us understand the influence life has on genetic function. Research has shown that what we do, what we are exposed to, and the internal and external environments have significant influence on the output of our genes.
openaire   +2 more sources

The modern versus extended evolutionary synthesis : sketch of an intra-genomic gene's eye view for the evolutionary-genetic underpinning of epigenetic and developmental evolution [PDF]

open access: yes, 2018
Studying the phenotypic evolution of organisms in terms of populations of genes and genotypes, the Modern Synthesis (MS) conceptualizes biological evolution in terms of 'inter-organismal' interactions among genes sitting in the different individual ...
Blancke, Stefaan   +2 more
core   +3 more sources

Genetics and Epigenetics in Asthma

open access: yesInternational Journal of Molecular Sciences, 2021
Asthma is one of the most common respiratory disease that affects both children and adults worldwide, with diverse phenotypes and underlying pathogenetic mechanisms poorly understood. As technology in genome sequencing progressed, scientific efforts were
P. Ntontsi   +4 more
semanticscholar   +1 more source

Epigenetics for the 21st-Century Biology Student

open access: yesJournal of Microbiology & Biology Education, 2019
Epigenetics, a rapidly emerging biological science, investigates changes in gene expression without any change to the primary DNA sequence. Epigenetics plays an important role in diverse areas, including nutritional sciences, psychology, and ...
Jonghoon Kang   +3 more
doaj   +1 more source

Understanding Health Inequalities Through the Lens of Social Epigenetics

open access: yesAnnual Review of Public Health, 2022
Longstanding racial/ethnic inequalities in morbidity and mortality persist in the United States. Although the determinants of health inequalities are complex, social and structural factors produced by inequitable and racialized systems are recognized as ...
Chantel L. Martin   +4 more
semanticscholar   +1 more source

Environmental epigenetics [PDF]

open access: yesHeredity, 2010
Epigenetics investigates heritable changes in gene expression that occur without changes in DNA sequence. Several epigenetic mechanisms, including DNA methylation and histone modifications, can change genome function under exogenous influence. We review current evidence indicating that epigenetic alterations mediate effects caused by exposure to ...
V. Bollati, A. Baccarelli
openaire   +2 more sources

Epigenetics of Aging and Aging-Associated Diseases

open access: yesInternational Journal of Molecular Sciences, 2021
Aging represents the multifactorial decline in physiological function of every living organism. Over the past decades, several hallmarks of aging have been defined, including epigenetic deregulation.
D. Saul, R. L. Kosinsky
semanticscholar   +1 more source

Epigenetic inheritance. Concepts, mechanisms and perspectives [PDF]

open access: yes, 2018
Parents' stressful experiences can influence an offspring's vulnerability to many pathological conditions, including psychopathologies, and their effects may even endure for several generations.
Lacal, Irene, Ventura, Rossella
core   +1 more source

Ethical implications of epigenetics in the era of personalized medicine

open access: yesClinical Epigenetics, 2022
Given the increasing research activity on epigenetics to monitor human diseases and its connection with lifestyle and environmental expositions, the field of epigenetics has attracted a great deal of interest also at the ethical and societal level.
J. Santaló, M. Berdasco
semanticscholar   +1 more source

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