Results 41 to 50 of about 495,214 (384)

Epigenetics Regulates Antitumor Immunity in Melanoma

Frontiers in Immunology, 2022
Melanoma is the most malignant skin cancer, which originates from epidermal melanocytes, with increasing worldwide incidence. The escape of immune surveillance is a hallmark of the tumor, which is manifested by the imbalance between the enhanced immune ...
Yuhan Chen, Yuhan Chen, Xiuli Yi, Ningyue Sun, Ningyue Sun, Weinan Guo, Chunying Li   +6 more
doaj   +1 more source

Epigenetic Metalloenzymes

Current Medicinal Chemistry, 2019
Epigenetics controls the expression of genes and is responsible for cellular phenotypes. The fundamental basis of these mechanisms involves in part the post-translational modifications (PTMs) of DNA and proteins, in particular, the nuclear histones. DNA can be methylated or demethylated on cytosine.
Blanquart, Christophe, Linot, Camille, Cartron, Pierre-François, Tomaselli, Daniela, Mai, Antonello, Bertrand, Philippe   +5 more
openaire   +5 more sources

Epigenetic Crosstalk [PDF]

Molecular Cell, 2001
In the November 15 issue of Nature, report that disruption of histone methylation in the fungus Neurospora crassa results in the elimination of DNA methylation. This demonstrates that chromatin structure can pattern DNA methylation and suggests that different epigenetic layers engage in complex crosstalk.
Ben-Porath, Ittai, Cedar, Howard
openaire   +2 more sources

Synthesizing the role of epigenetics in the response and adaptation of species to climate change in freshwater ecosystems [PDF]

, 2018
Freshwater ecosystems are amongst the most threatened ecosystems on Earth. Currently, climate change is one of the most important drivers of freshwater transformation and its effects include changes in the composition, biodiversity and functioning of ...
Allen, Allendorf, Alley, Andrewartha, Anway, Araújo, Ardura, Artemov, Asselman, Asselman, Avise, Baccarelli, Baerwald, Baudo, Bell, Berg, Bernardi, Bernstein, Bianchini, Bind, Bird, Bird, Blake, Bossdorf, Boutin, Brander, Bräutigam, Burggren, Bush, Carpenter, Cañedo-Argüelles, Chown, Clarke, Corcoran, Crozier, Dai, Dallas, Daxinger, Denissenko, Detrich, Dudgeon, Durance, Eros, Fasola, Feil, Fenoglio, Foley, Friberg, Fulneček, Garg, Gienapp, Glastad, Goldberg, Gonçalves, Guillette, Hanson, Harris, Heino, Henry, Hering, Hernando-Herraez, Ho, Hoegh-Guldberg, Hoffmann, Hu, Jabbari, Jablonka, Jackson, Jackson, Jaenisch, Janssens, Jiang, Karell, Karr, Kefford, Keller, Kelly, Klimenko, Klironomos, Kouzarides, Kronholm, Kronholm, Kumar, Kurdyukov, Laland, Laland, Lan, Latta, Leung, Lighten, Liu, Loureiro, Loureiro, Lämke, Manjrekar, Markovic, Martinez-Sales, Martínez-Jerónimo, Matthews, Mattick, Meissner, Mendizabal, Merilä, Merilä, Michener, Mimura, Minshull, Mirbahai, Mohseni, Moore, Mudbhary, Mulholland, Munday, Nabel, Nielsen, Norouzitallab, Parichy, Park, Pestana, Peterson, Pigliucci, Pigliucci, Pu, Qu, Rey, Ribeiro, Rinn, Ryan, Sarda, Scheiner, Scheiner, Schindler, Schrey, Shaw, Shea, Solan, Srinageshwar, Stief, Sun, Suter, Suzuki, Szabo, Sáez, Urich, Vandegehuchte, Vandegehuchte, Vannier, Varriale, Varriale, Varriale, Venâncio, Verhoeven, Verhoeven, Vogt, Vogt, Vogt, Wang, Wang, Weider, Weinberg, Weyrich, Willbanks, Williams, Wong, Woodward, Woodward, WWAP   +166 more
core   +1 more source

Machine learning and clinical epigenetics: a review of challenges for diagnosis and classification

Clinical Epigenetics, 2020
Machine learning is a sub-field of artificial intelligence, which utilises large data sets to make predictions for future events. Although most algorithms used in machine learning were developed as far back as the 1950s, the advent of big data in ...
S. Rauschert, K. Raubenheimer, P. Melton, P. Melton, P. Melton, Rae-Chi Huang   +5 more
semanticscholar   +1 more source

Comprehensive evaluation of genome-wide 5-hydroxymethylcytosine profiling approaches in human DNA

Epigenetics & Chromatin, 2017
Background The discovery that 5-methylcytosine (5mC) can be oxidized to 5-hydroxymethylcytosine (5hmC) by the ten-eleven translocation (TET) proteins has prompted wide interest in the potential role of 5hmC in reshaping the mammalian DNA methylation ...
Ksenia Skvortsova, Elena Zotenko, Phuc-Loi Luu, Cathryn M. Gould, Shalima S. Nair, Susan J. Clark, Clare Stirzaker   +6 more
doaj   +1 more source

“Epic-Genetics”: An exploration of preservice helping professionals’ (mis)understanding of epigenetic influences on human development

Teaching & Learning Inquiry: The ISSOTL Journal, 2020
Mental health researchers emphasize the importance of practitioner understanding of biology-environment interplay. Accordingly, our goal of the study described in this article was to understand students’ preconceptions and misconceptions about biological
Kate E. Snyder, Caroline M. Pittard, Allison Fowler, Corey T. Watson   +3 more
doaj   +1 more source

Role of epigenetics in cardiovascular diseases: An out and out check

Intelligent Pharmacy, 2023
Epigenetics is a rapidly growing field that deals with the study of heritable changes in gene expression that occur without a change in DNA sequence.
Rufaida Wasim, Tarique Mahmood, Mohammed Haris Siddiqui, Aditya Singh, Asad Ahmad, Farogh Ahsan   +5 more
doaj   +1 more source

Viral Epigenetics [PDF]

, 2014
DNA tumor viruses including members of the polyomavirus, adenovirus, papillomavirus, and herpes virus families are presently the subject of intense interest with respect to the role that epigenetics plays in control of the virus life cycle and the transformation of a normal cell to a cancer cell.
Barry I, Milavetz, Lata, Balakrishnan
openaire   +2 more sources

Malaria Epigenetics [PDF]

Cold Spring Harbor Perspectives in Medicine, 2017
Organisms with identical genome sequences can show substantial differences in their phenotypes owing to epigenetic changes that result in different use of their genes. Epigenetic regulation of gene expression plays a key role in the control of several fundamental processes in the biology of malaria parasites, including antigenic variation and sexual ...
Cortés, Alfred, Deitsch, Kirk W.
openaire   +3 more sources