Results 51 to 60 of about 458,162 (417)
Maternal SMCHD1 regulates Hox gene expression and patterning in the mouse embryo
Nature Communications, 2022 Parents transmit both genetic and epigenetic information to their offspring, with maternal effect genes being critical regulators of the offspring epigenome.
Natalia Benetti +7 more
doaj +1 more source
The danger of epigenetics misconceptions (epigenetics and stuff…) [PDF]
Biochemistry and Cell Biology, 2015 Within the past two decades, the fields of chromatin structure and function and transcription regulation research started to fuse and overlap, as evidence mounted to support a very strong regulatory role in gene expression that was associated with histone post-translational modifications, DNA methylation, as well as various chromatin-associated ...
openaire +4 more sources
Transcriptomic profiling disclosed the role of DNA methylation and histone modifications in tumor-infiltrating myeloid-derived suppressor cell subsets in colorectal cancer [PDF]
, 2020 Increased numbers of myeloid-derived suppressor cells (MDSCs) are positively correlated with poor prognosis and reduced survivals of cancer patients. They play central roles in tumor immune evasion and tumor metastasis.
Abu Nada, M +9 more
core +3 more sources
Critical Care Medicine, 2020 Objectives: Recent evidence from the fields of microbiology and immunology, as well as a small number of human sepsis studies, suggest that epigenetic regulation may play a central role in the pathogenesis of sepsis. The term “epigenetics” refers to regulatory mechanisms that control gene expression but are not related to ...
Pedro Castelo-Branco +6 more
openaire +4 more sources
Cold Spring Harbor Perspectives in Medicine, 2017 Organisms with identical genome sequences can show substantial differences in their phenotypes owing to epigenetic changes that result in different use of their genes. Epigenetic regulation of gene expression plays a key role in the control of several fundamental processes in the biology of malaria parasites, including antigenic variation and sexual ...
Cortés, Alfred, Deitsch, Kirk W.
openaire +3 more sources
Modeling epigenetic evolutionary algorithms: An approach based on the epigenetic regulation process [PDF]
arXiv, 2021 Many biological processes have been the source of inspiration for heuristic methods that generate high-quality solutions to solve optimization and search problems. This thesis presents an epigenetic technique for Evolutionary Algorithms, inspired by the epigenetic regulation process, a mechanism to better understand the ability of individuals to adapt ...
arxiv
Drawing a Waddington landscape to capture dynamic epigenetics [PDF]
Biol. Cell. 105, 576-584 (2013), 2016 Epigenetics is most often reduced to chromatin marking in the current literature, whereas this notion was initially defined in a more general context. This restricted view ignores that epigenetic memories are in fact more robustly ensured in living systems by steady state mechanisms with permanent molecule renewal.
arxiv +1 more source
Non-coding RNAs as regulators in epigenetics (Review).
Oncology Report, 2017 Epigenetics is a discipline that studies heritable changes in gene expression that do not involve altering the DNA sequence. Over the past decade, researchers have shown that epigenetic regulation plays a momentous role in cell growth, differentiation ...
Jianwei Wei +3 more
semanticscholar +1 more source
Epigenetic targets in the treatment of cancer [PDF]
, 2017 Descpription of epigenetic targets in the treatment of solid ...
CODACCI PISANELLI, Giovanni
core +1 more source
Epigenetics Algorithms: Self-Reinforcement-Attention mechanism to regulate chromosomes expression [PDF]
arXiv, 2023 Genetic algorithms are a well-known example of bio-inspired heuristic methods. They mimic natural selection by modeling several operators such as mutation, crossover, and selection. Recent discoveries about Epigenetics regulation processes that occur "on top of" or "in addition to" the genetic basis for inheritance involve changes that affect and ...
arxiv