Results 51 to 60 of about 369,301 (351)

Non-coding RNAs as regulators in epigenetics (Review).

Oncology Report, 2017
Epigenetics is a discipline that studies heritable changes in gene expression that do not involve altering the DNA sequence. Over the past decade, researchers have shown that epigenetic regulation plays a momentous role in cell growth, differentiation ...
Jianwei Wei, Kai Huang, Chao Yang, C. Kang   +3 more
semanticscholar   +1 more source

From 1957 to Nowadays: A Brief History of Epigenetics

International Journal of Molecular Sciences, 2020
Due to the spectacular number of studies focusing on epigenetics in the last few decades, and particularly for the last few years, the availability of a chronology of epigenetics appears essential.
P. Peixoto, P. Cartron, Aurélien A. Sérandour, E. Hervouet   +3 more
semanticscholar   +1 more source

Epigenetic Regulation and Measurement of Epigenetic Changes [PDF]

Biological Research For Nursing, 2012
Epigenetic mechanisms provide an adaptive layer of control in the regulation of gene expression that enables an organism to adjust to a changing environment. Epigenetic regulation increases the functional complexity of deoxyribonucleic acid (DNA) by altering chromatin structure, nuclear organization, and transcript stability.
Stephens, Kimberly E, Miaskowski, Christine A, Levine, Jon D, Pullinger, Clive R, Aouizerat, Bradley E   +4 more
openaire   +5 more sources

Epigenetics of Sepsis

Critical Care Medicine, 2020
Objectives: Recent evidence from the fields of microbiology and immunology, as well as a small number of human sepsis studies, suggest that epigenetic regulation may play a central role in the pathogenesis of sepsis. The term “epigenetics” refers to regulatory mechanisms that control gene expression but are not related to ...
Pedro Castelo-Branco, Alexandra Binnie, Claudia C. dos Santos, Claudia C. dos Santos, Pingzhao Hu, Gabriela Carrasqueiro, Jennifer L Y Tsang   +6 more
openaire   +4 more sources

Epigenetics and Lifestyle [PDF]

Epigenomics, 2011
The concept of 'lifestyle' includes different factors such as nutrition, behavior, stress, physical activity, working habits, smoking and alcohol consumption. Increasing evidence shows that environmental and lifestyle factors may influence epigenetic mechanisms, such as DNA methylation, histone acetylation and miRNA expression.
J. A. Alegría Torres, A. Baccarelli, V. Bollati   +2 more
openaire   +3 more sources

Complete loss of H3K9 methylation dissolves mouse heterochromatin organization

Nature Communications, 2021
Histone H3K9 methylation (H3K9me) states define repressed chromatin in eukaryotic cells. Here the authors reveal complete loss of all H3K9me in mammalian cells through successive deletion of H3K9 methyltransferase genes that results in the dissolution of
Thomas Montavon, Nicholas Shukeir, Galina Erikson, Bettina Engist, Megumi Onishi-Seebacher, Devon Ryan, Yaarub Musa, Gerhard Mittler, Alexandra Graff Meyer, Christel Genoud, Thomas Jenuwein   +10 more
doaj   +1 more source

Social context prevents heat hormetic effects against mutagens during fish development

FEBS Letters, EarlyView.
This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere, Claudio Silva De Freitas, Adam Bates, Kenneth B. Storey, Pedro Beltran‐Alvarez, Katharina C. Wollenberg Valero   +5 more
wiley   +1 more source

The social construction of the social epigenome and the larger biological context

Epigenetics & Chromatin, 2020
Epigenetics researchers in developmental, cell, and molecular biology greatly diverge in their understanding and definitions of epigenetics. In contrast, social epigeneticists, e.g., sociologists, scholars of STS, and behavioural scientists, share a ...
Ute Deichmann
doaj   +1 more source

Epigenetics and aging

Science Advances, 2016
Researchers review how random changes and our environment (for example, diet) determines our life span. Over the past decade, a growing number of studies have revealed that progressive changes to epigenetic information accompany aging in both dividing ...
Sangita Pal, J. Tyler
semanticscholar   +1 more source

Decoding the dual role of autophagy in cancer through transcriptional and epigenetic regulation

FEBS Letters, EarlyView.
Transcriptional and epigenetic regulation controls autophagy, which exerts context‐dependent effects on cancer: Autophagy suppresses tumorigenesis by maintaining cellular homeostasis or promotes tumor progression by supporting survival under stress. In this “In a Nutshell” article, we explore the intricate mechanisms of the dual function of autophagy ...
Young Suk Yu, Ik Soo Kim, Sung Hee Baek
wiley   +1 more source