Results 101 to 110 of about 87,804 (313)
Frontiers in Cellular Neuroscience, 2019 The development of the human cerebral cortex is a complex and dynamic process, in which neural stem cell proliferation, neuronal migration, and post-migratory neuronal organization need to occur in a well-organized fashion.
Elena Perenthaler +3 more
doaj +1 more source
Women's perception, attitudes, and intended behavior towards predictive epigenetic risk testing for female cancers in 5 European countries: A cross-sectional online survey [PDF]
, 2019 BACKGROUND: Epigenetic markers might be used for risk-stratifying cancer screening and prevention programs in the future. Although the clinical utility of consequent epigenetic tests for risk stratification is yet to be proven, successful adoption into ...
Pashayan, N. +3 more
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Cancer Communications, EarlyView.Abstract Background Gastric cancer peritoneal metastasis is clinically challenging, given the limited treatment options and poor prognosis. The molecular mechanisms that precede gastric cancer peritoneal metastasis, known as the pre‐metastatic niche (PMN), and its relationship with N6‐methyladenosine (m6A) modification remain unclear.
Song Li +23 more
wiley +1 more source
Epigenomics and the Microbiota [PDF]
Toxicologic Pathology, 2014 The mammalian gastrointestinal tract is home to trillions of commensal microorganisms that collectively make up the intestinal microbiota. These microbes are important environmental factors that regulate homeostasis, and alterations in the composition of the microbiota have been associated with several diseases, including inflammatory bowel disease ...
openaire +3 more sources
The chicken erythrocyte epigenome [PDF]
Epigenetics & Chromatin, 2016 Transcriptional regulation is impacted by multiple layers of genome organization. A general feature of transcriptionally active chromatin is sensitivity to DNase I and association with acetylated histones. However, very few of these active DNase I-sensitive domains, such as the chicken erythrocyte β-globin domain, have been identified and characterized.
Jahan, Sanzida +5 more
openaire +2 more sources
Highly Sensitive, Low‐Cost Deep‐UV Resonant Raman Microspectroscopy Systems
Chemistry–Methods, EarlyView.Low‐cost deep UV resonant Raman microscope for chemical sensing and imaging has been developed and its performance has been experimentally validated for several potential applications. Multimodal imaging capabilities of a new instrument have been demonstrated as well.
Joseph Harrington +5 more
wiley +1 more source
DNA methylation and socioeconomic status in a Mexican-American birth cohort. [PDF]
, 2018 Background: Maternal social environmental stressors during pregnancy are associated with adverse birth and child developmental outcomes, and epigenetics has been proposed as a possible mechanism for such relationships.
Coker, Eric +4 more
core +1 more source
Clinical Pharmacology &Therapeutics, EarlyView.Overview of a multi‐omics based drug repurposing strategy. The systematic drug repurposing strategy included the following steps: (1) osteoporosis driver signaling networks were identified from multi‐omics data; (2) drug functional modules were obtained using a network fusion approach to integrate drug similarity information; (3) all drugs were ranked ...
Dan‐Yang Liu +21 more
wiley +1 more source
Reduced NCOR2 expression accelerates androgen deprivation therapy failure in prostate cancer
Cell Reports, 2021 Summary: This study addresses the roles of nuclear receptor corepressor 2 (NCOR2) in prostate cancer (PC) progression in response to androgen deprivation therapy (ADT).
Mark D. Long +14 more
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Frontiers in Oncology, 2012 Human papillomavirus (HPV) infection is well established as etiological agent responsible for a number of pathologies affecting the stratified epithelia of skin and anogenital sites.
Efterpi eKostareli +4 more
doaj +1 more source