Results 21 to 30 of about 57,982 (252)
Microorganisms, 2021 DNA methylation is a common, but not universal, epigenetic modification that plays an important role in multiple cellular processes. While definitely settled for numerous plant, mammalian, and bacterial species, the genome methylation in different fungal
Monika Kubiak-Szymendera +3 more
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Mobile DNA, 2017 Background Intracisternal A particle (IAP) is one of the most transpositionally active retrotransposons in the mouse genome, but its expression varies between cell types. This variation is believed to arise from differences in the epigenetic state (e.g.,
Ken-ichi Shimosuga +3 more
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DNA methylation profiles unique to Kalahari KhoeSan individuals
Epigenetics, 2021 Genomes of KhoeSan individuals of the Kalahari Desert provide the greatest understanding of single nucleotide diversity in the human genome. Compared with individuals in industrialized environments, the KhoeSan have a unique foraging and hunting ...
Alexander Goncearenco +7 more
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Reduced NCOR2 expression accelerates androgen deprivation therapy failure in prostate cancer
Cell Reports, 2021 Summary: This study addresses the roles of nuclear receptor corepressor 2 (NCOR2) in prostate cancer (PC) progression in response to androgen deprivation therapy (ADT).
Mark D. Long +14 more
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Epigenome-wide association results of maternal age in NFCS newborns.
, 2016 Volcano plot showing the relationship between the effect magnitude (coefficient) and strength of association (p-value) for Model1. The red horizontal line denotes the strict threshold for epigenome-wide significance based on a conservative Bonferroni ...
Zongli Xu (36200) +12 more
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Epigenome-wide association study of motor impairment in preterm and low birth weight infants
, 2021 This thesis is an Epigenome Wide association study on motor impairment in preterm and low birth weight infants. Five differentially methylated probes and 35 differentially methylated regions that are potentially linked to general motor impairment were ...
Jennifer Snowball (19985694)
core
Restructuring of Lamina-Associated Domains in Senescence and Cancer
Cells, 2022 Induction of cellular senescence or cancer is associated with a reshaping of the nuclear envelope and a broad reorganization of heterochromatin. At the periphery of mammalian nuclei, heterochromatin is stabilized at the nuclear lamina via lamina ...
Aurélie Bellanger +3 more
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Cell Reports, 2021 Summary: Human induced pluripotent stem cells (hiPSCs) show variable differentiation potential due to their epigenomic heterogeneity, whose extent/attributes remain unclear, except for well-studied elements/chromosomes such as imprints and the X ...
Shihori Yokobayashi +10 more
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The Toolbox for Untangling Chromosome Architecture in Immune Cells
Frontiers in Immunology, 2021 The code of life is not only encrypted in the sequence of DNA but also in the way it is organized into chromosomes. Chromosome architecture is gradually being recognized as an important player in regulating cell activities (e.g., controlling ...
Shuai Liu, Keji Zhao
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, 2021 A complex interplay of genetic and environmental risk factors influence global brain structural alterations associated with brain health and disease.
Stolicyn Aleks (11653938) +19 more
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