Results 51 to 60 of about 63,478 (191)
Circulation Research, 2018 The advent of high-throughput epigenome mapping technologies has ushered in a new era of multiomics where powerful tools can now delineate and record different layers of genomic output. Integrating various components of the epigenome from these multiomics measurements allows the interrogation of cellular heterogeneity in addition to the discovery of ...
Kevin C, Wang, Howard Y, Chang
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Scientific Reports, 2017 Alternative splicing is a mechanism for increasing protein diversity from a limited number of genes. Studies have demonstrated that aberrant regulation in the alternative splicing of apoptotic gene transcripts may contribute to the development of cancer.
Chien-Chin Lee +6 more
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Global Reprogramming of Apoptosis-Related Genes during Brain Development
Cells, 2021 To enable long-term survival, mammalian adult neurons exhibit unique apoptosis competence. Questions remain as to whether and how neurons globally reprogram the expression of apoptotic genes during development.
Wei Jiang, Liang Chen, Sika Zheng
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Nutrición e Inflamación: mediadores epigenéticos
Revista Española de Nutrición Humana y Dietética, 2020 III Congreso de Alimentación, Nutrición y Dietética. Combinar la nutrición comunitaria y personalizada: nuevos retos.
Lidia Daimiel +4 more
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Biology, 2022 Reactivation of fetal cardiac genes, including those encoding atrial natriuretic peptide (ANP) and brain natriuretic peptide (BNP), is a key feature of pathological cardiac remodeling and heart failure.
Hideaki Inazumi, Koichiro Kuwahara
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Nature CommunicationsDNA damage compromises not only genome stability but also chromatin integrity, which plays a central role in controlling cell identity. Chromatin repair entails the deposition of new histones at sites of DNA damage.
Alexandre Plessier +5 more
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Marine-Derived Secondary Metabolites as Promising Epigenetic Bio-Compounds for Anticancer Therapy
Marine Drugs, 2020 Sessile organisms such as seaweeds, corals, and sponges continuously adapt to both abiotic and biotic components of the ecosystem. This extremely complex and dynamic process often results in different forms of competition to ensure the maintenance of an ...
Mariarosaria Conte +3 more
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Transcriptional repression shapes the identity and function of tissue macrophages
FEBS Open Bio, 2021 The changing extra‐ and intracellular microenvironment calls for rapid cell fate decisions that are precisely and primarily regulated at the transcriptional level.
Krisztian Bene +2 more
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Cancer Medicine, 2019 Next‐generation sequencing (NGS) technology is currently used to establish mutational profiles in many heterogeneous diseases. The aim of this study was to evaluate the mutational spectrum in Taiwanese patients with colorectal cancer (CRC) to help ...
Ya‐Sian Chang +6 more
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Maternal obesity blunts antimicrobial responses in fetal monocytes
eLife, 2023 Maternal pre-pregnancy (pregravid) obesity is associated with adverse outcomes for both mother and offspring. Amongst the complications for the offspring is increased susceptibility and severity of neonatal infections necessitating admission to the ...
Suhas Sureshchandra +6 more
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