Results 61 to 70 of about 63,478 (191)

Vitamin D and the epigenome [PDF]

Frontiers in Physiology, 2014
Epigenetic mechanisms play a crucial role in regulating gene expression. The main mechanisms involve methylation of DNA and covalent modifications of histones by methylation, acetylation, phosphorylation, or ubiquitination. The complex interplay of different epigenetic mechanisms is mediated by enzymes acting in the nucleus.
Fetahu, Irfete S., Höbaus, Julia, Kállay, Enikő   +2 more
openaire   +3 more sources

Mitotic chromatin marking governs the segregation of DNA damage

Nature Communications
The faithful segregation of intact genetic material and the perpetuation of chromatin states through mitotic cell divisions are pivotal for maintaining cell function and identity across cell generations.
Juliette Ferrand, Juliette Dabin, Odile Chevallier, Matteo Kane-Charvin, Ariana Kupai, Joel Hrit, Scott B. Rothbart, Sophie E. Polo   +7 more
doaj   +1 more source

Epigenomics in Environmental Health [PDF]

Frontiers in Genetics, 2011
This review considers the emerging relationships between environmental factors and epigenetic alterations and the application of genome-wide assessments to better define these relationships. First we will briefly cover epigenetic programming in development, one-carbon metabolism, and exposures that may disrupt normal developmental programming of ...
Christensen, Brock C., Marsit, Carmen J.
openaire   +3 more sources

Epigenome-wide meta-analysis of DNA methylation and childhood asthma

, 2019
Background: Epigenetic mechanisms, including methylation, can contribute to childhood asthma. Identifying DNA methylation profiles in asthmatic patients can inform disease pathogenesis.
Maguire, RL (15726821), Wang, T (15538919), Huang, R-C (15628547), Merid, SK (15719168), Bustamante, M (15684431), Sikdar, S (15726782), Kere, J (15719339), Hoyo, C (15726839), Soderhall, C (15719321), Almqvist, C (15719324), Felix, JF (15719357), Page, CM (15719246), Ortqvist, AK (15726830), Lee, MK (15630839), Rezwan, FI (15719204), Burchard, EG (15726848), Phillip Melton (14744191), Lahti, J (15605816), Kupers, LK (15719177), Karmaus, W (15719243), Arshad, SH (15719276), Haberg, SE (15613916), Ward, J (15483944), Breton, CV (15719213), Relton, CL (15719255), Kazmi, N (15719198), Nystad, W (15719306), Hu, D (15600911), Binder, EB (15719282), Henderson, AJ (15726851), Baiz, N (15719219), Zhao, S (15568043), Corpeleijn, E (15719228), Gilliland, F (15726824), Gao, L (15564152), Burrows, K (15726797), Xu, C-J (15719333), Melen, E (15719366), Nohr, EA (15719237), Anto, JM (15719315), Vonk, JM (15719288), Richards, AJ (15726818), Hollams, E (15726815), Arathimos, R (15726803), Bell, DA (15726812), Holloway, JW (15719279), Pershagen, G (15719210), Ruiz-Arenas, C (15726785), Jima, DD (15726800), Jaddoe, VWV (15628544), Oh, SS (15726791), Wielscher, M (15719348), Magnus, MC (15726827), Bennett, BD (15521399), Reischl, E (15726842), Koletzko, B (15628757), Brunekreef, B (15637823), Kull, I (15719297), Sunyer, J (15545984), Karlsson, R (15619118), Bergstrom, A (15719258), Sebert, S (15717212), den Dekker, HT (15726779), Duijts, L (15719234), Raikkonen, K (15605957), Snieder, H (15595835), Murphy, SK (15726845), Kajantie, E (15726422), Reese, SE (15719336), Yang, IV (15726794), Rzehak, P (15628646), Annesi-Maesano, I (15719183), Laprise, C (15726806), Ullemar, V (15726788), Eng, C (15726833), Jarvelin, M-R (15717209), Koppelman, GH (15719360), Sharp, GC (15719174), Madore, A-M (15726809), Gruzieva, O (15719330), Liu, AH (15726836), Schwartz, DA (15510869), Grote, V (15662681), London, SJ (15719363)   +83 more
core   +1 more source

Dietary Modulation of the Epigenome [PDF]

Physiological Reviews, 2018
Epigenetics is the study of heritable mechanisms that can modify gene activity and phenotype without modifying the genetic code. The basis for the concept of epigenetics originated more than 2,000 yr ago as a theory to explain organismal development. However, the definition of epigenetics continues to evolve as we identify more of the components that ...
Folami Y, Ideraabdullah, Steven H, Zeisel   +1 more
openaire   +2 more sources

Epigenome-wide meta-analysis of B cell DNA methylation in three combined cohorts for HIV infection.

Epigenome-wide meta-analysis of B cell DNA methylation in three combined cohorts for HIV infection.
Vincent C. Marconi (8232468), Bradley E. Aouizerat (9678480), Xinyu Zhang (14029), Mardge H. Cohen (7923182), Ral E. Vandenhoudt (18137407), Zuoheng Wang (223293), Ying Hu (14950), Ke Xu (134879), Amy C. Justice (9185633), Chunhua Yan (392686)   +9 more
core   +1 more source

Epigenome-wide differential DNA methylation between HIV-infected and uninfected individuals

, 2016
Epigenetic control of human immunodeficiency virus-1 (HIV-1) genes is critical for viral integration and latency. However, epigenetic changes in the HIV-1-infected host genome have not been well characterized.
Brinda Emu (231184), John H. Krystal (197601), Xinyu Zhang (14029), Amy C. Justice (229955), Hongyu Zhao (4728), Zuoheng Wang (223293), Richard E. Sutton (2939580), Ying Hu (14950), Ke Xu (134879), Guilin Wang (37620), Eric O. Johnson (116487)   +10 more
core   +1 more source

Epigenomics and chromatin dynamics [PDF]

Genome Biology, 2012
A report of the 'Joint Keystone Symposium on Epigenomics and Chromatin Dynamics', Keystone, Colorado, 17-22 January 2012.
Akopian, Veronika, Chan, Michelle, Clement, Kendell, Galonska, Christina, Gifford, Casey, Lehtola, Elizabeth, Liao, Jing, Samavarchi-Tehrani, Payman, Sindhu, Camille, Smith, Zachary, Tsankov, Alexander M., Webster, Jamie Orme, Zhang, Yingying, Ziller, Michael, Meissner, Alexander   +14 more
openaire   +5 more sources

Cerebral Organoids Recapitulate Epigenomic Signatures of the Human Fetal Brain

Cell Reports, 2016
Organoids derived from human pluripotent stem cells recapitulate the early three-dimensional organization of the human brain, but whether they establish the epigenomic and transcriptional programs essential for brain development is unknown.
Chongyuan Luo, Madeline A. Lancaster, Rosa Castanon, Joseph R. Nery, Juergen A. Knoblich, Joseph R. Ecker   +5 more
doaj   +1 more source

Epigenome-wide meta-analysis of NK cell DNA methylation three combined cohorts for HIV infection.

Epigenome-wide meta-analysis of NK cell DNA methylation three combined cohorts for HIV infection.
Vincent C. Marconi (8232468), Bradley E. Aouizerat (9678480), Xinyu Zhang (14029), Mardge H. Cohen (7923182), Ral E. Vandenhoudt (18137407), Zuoheng Wang (223293), Ying Hu (14950), Ke Xu (134879), Amy C. Justice (9185633), Chunhua Yan (392686)   +9 more
core   +1 more source