Results 101 to 110 of about 27,140 (186)

Epigenome [PDF]

, 2019
openaire   +1 more source

Challenges in Bringing Pangenome Research Into Breeding: A Case Study in Rice

Plant Biotechnology Journal, EarlyView.
ABSTRACT Crop breeding has entered the pangenomics era, unlocking a far more comprehensive view of genetic diversity than a single reference genome can capture. In rice (Oryza sativa), a staple crop critical to global food security, the construction of pangenome resources has uncovered extensive structural variations (SVs), presence/absence variations (
Shuai Nie, Fangping Li, Risheng Li, Jian Wang, Yamei Ma, Chon Kit Kenneth Chan, Junliang Zhao, Haifei Hu   +7 more
wiley   +1 more source

Multi-omics-driven biomarker discovery in autoimmune diseases: a comprehensive review. [PDF]

Front Immunol
Zhang Y, Xu H, Xu L, Jiang S, Yu Y, Zhao H.   +5 more
europepmc   +1 more source

The dynamic epigenome [PDF]

Nature Structural & Molecular Biology, 2013
openaire   +2 more sources

Single‐Cell CRISPR: An Efficient Strategy for Decoding Plant Cis‐Regulatory Complexity

Plant Biotechnology Journal, EarlyView.
ABSTRACT The generation of complex traits involves the coordinated interplay of multiple gene networks. Elucidating the function of transcriptional cis‐regulatory elements (CREs) in regulating gene expression is crucial for understanding complex regulatory pathways and improving our ability to modify macro‐phenotypes.
Yuanhang Zhang, Xuanxuan Luo, Hongbin Li, Shuangxia Jin, Xianlong Zhang, Maojun Wang   +5 more
wiley   +1 more source

Integrative multi-omics profiling for early diagnosis, stratification and personalized management of chronic kidney disease: a new paradigm. [PDF]

Clin Exp Med
Li Y, Taherkhani S, Saidov K, Matniyozova M.   +3 more
europepmc   +1 more source

A dynamic epigenetic perspective on above‐ and belowground phenotypic responses to drought: Insights from global DNA methylation in Erodium cicutarium

Plant Biology, EarlyView.
Our factorial experimental design investigates the relationships between DNA methylation, plant development and individual fitness under stress in Erodium cicutarium. We found that epigenetic modifications associated to 5‐azacytidine seed treatment desynchronized plant growth and delayed flowering.
C. Alonso, M. Medrano, C. M. Herrera
wiley   +1 more source

Pathway-guided architectures for interpretable AI in biological research. [PDF]

Comput Struct Biotechnol J
Zhou Q, Madala NS, Huang C.
europepmc   +1 more source

Pituitary Neuroendocrine Tumor or Pituitary Adenoma? Let's Ask the Epigenome! [PDF]

Endocr Pathol
Dottermusch M.
europepmc   +1 more source

A multi‐omics investigation of sarcopenia and frailty: Integrating genomic, epigenomic and telomere length data

Experimental Physiology, EarlyView.
Abstract Sarcopenia and frailty are complex geriatric syndromes influenced by a combination of genetic and environmental factors. Recent studies suggest that specific genetic variants, DNA methylation patterns and shortened telomeres are associated with age‐related diseases and might contribute to the development of both sarcopenia and frailty. In this
Valentina Ginevičienė, Erinija Pranckevičienė, Alina Urnikytė, Laura Jurkūnaitė, Kristijona Gutauskaitė, Rūta Dadelienė, Justina Kilaitė, Ieva Eglė Jamontaitė, Asta Mastavičiūtė, Ildus I. Ahmetov, Vidmantas Alekna   +10 more
wiley   +1 more source