Results 71 to 80 of about 64,265 (410)
The Epigenome in Atherosclerosis [PDF]
, 2020 AbstractEmerging evidence suggests the growing importance of “nongenetic factors” in the pathogenesis of atherosclerotic vascular disease. Indeed, the inherited genome determines only part of the risk profile as genomic approaches do not take into account additional layers of biological regulation by “epi”-genetic changes.
Francesco Paneni, Sarah Costantino
openaire +2 more sources
Identifying OCRs in cfDNA WGS Data by Correlation Clustering [PDF]
arXiv, 2022 In the recent decade, the emergence of liquid biopsy has significantly improved cancer monitoring and detection. Dying cells, including those originating from tumors, shed their DNA into the bloodstream and contribute to a pool of circulating fragments called cell-free DNA (cfDNA).
arxiv
PLoS ONE, 2021 We evaluated the utility of leucocyte epigenomic-biomarkers for Alzheimer’s Disease (AD) detection and elucidates its molecular pathogeneses. Genome-wide DNA methylation analysis was performed using the Infinium MethylationEPIC BeadChip array in 24 late ...
R. Bahado-Singh +13 more
semanticscholar +1 more source
Probing the cancer genome [PDF]
, 2011 A report on the Keystone Symposium 'Cancer Genomics and Epigenomics', Taos, USA, 19-24 February ...
Greulich, Heidi E.
core +1 more source
Epigenetic Biomarkers for Environmental Exposures and Personalized Breast Cancer Prevention. [PDF]
, 2020 Environmental and lifestyle factors are believed to account for >80% of breast cancers; however, it is not well understood how and when these factors affect risk and which exposed individuals will actually develop the disease.
Park, Hannah Lui
core +1 more source
Quality control and evaluation of plant epigenomics data
The Plant Cell, 2021 Epigenomics is the study of molecular signatures associated with discrete regions within genomes, many of which are important for a wide range of nuclear processes. The ability to profile the epigenomic landscape associated with genes, repetitive regions,
Robert J. Schmitz +10 more
semanticscholar +1 more source
Integrating Epigenomics into the Understanding of Biomedical Insight
Bioinformatics and Biology Insights, 2016 Epigenetics is one of the most rapidly expanding fields in biomedical research, and the popularity of the high-throughput next-generation sequencing (NGS) highlights the accelerating speed of epigenomics discovery over the past decade.
Yixing Han, Ximiao He
doaj +1 more source
Scientific Reports, 2023 Ectopic fat deposition is more strongly associated with obesity-related health problems including type 2 diabetes mellitus (T2DM), cardiovascular diseases (CVD), hypothyroidism, arthritis, etc.
Sunandini Ghosh +4 more
doaj +1 more source
From obesity resistance to obesity prediction and prevention? [PDF]
, 2016 Comment on: Regulation of hypothalamic neuropeptides gene expression in diet induced obesity resistant rats: possible targets for obesity prediction?
Cassano, Tommaso, Gaetani, Silvana
core +4 more sources
Current Opinion in Nephrology and Hypertension, 2020 Epigenetic modifications are reversible changes to a cell's DNA or histones that alter gene expression but not DNA sequence. The present review will explore epigenomic profiling and bioinformatics techniques for the study of kidney development and disease.Reversible DNA and histone modifications influence chromatin accessibility and can be measured by ...
Nicolas Ledru +2 more
openaire +3 more sources