Results 11 to 20 of about 2,478,278 (345)
Epithelial barrier dysfunction in ocular allergy [PDF]
Allergy, 2021 The epithelial barrier is the first line of defense that forms a protective barrier against pathogens, pollutants, and allergens. Epithelial barrier dysfunction has been recently implicated in the development of allergic diseases such as asthma, atopic ...
Neera Singh +3 more
semanticscholar +5 more sources
Epithelial Barrier Dysfunction in Chronic Respiratory Diseases [PDF]
Frontiers in Physiology, 2021 Mucosal surfaces are lined by epithelial cells, which provide a complex and adaptive module that ensures first-line defense against external toxics, irritants, antigens, and pathogens.
F. Carlier +2 more
semanticscholar +5 more sources
Celiac Disease: Role of the Epithelial Barrier [PDF]
Cellular and Molecular Gastroenterology and Hepatology, 2017 In celiac disease (CD) a T-cell–mediated response to gluten is mounted in genetically predisposed individuals, resulting in a malabsorptive enteropathy histologically highlighted by villous atrophy and crypt hyperplasia.
Fromm, Michael +3 more
core +6 more sources
Environmental factors in epithelial barrier dysfunction. [PDF]
Journal of Allergy and Clinical Immunology, 2020 The main interfaces controlling and attempting to homeostatically balance communications between the host and the environment are the epithelial barriers of the skin, gastrointestinal system, and airways. The epithelial barrier constitutes the first line of physical, chemical, and immunologic defenses and provides a protective wall against ...
Z. Çelebi Sözener +4 more
semanticscholar +4 more sources
Inflammatory and Microbiota-Related Regulation of the Intestinal Epithelial Barrier
Frontiers in Nutrition, 2021 The intestinal epithelial barrier (IEB) is one of the largest interfaces between the environment and the internal milieu of the body. It is essential to limit the passage of harmful antigens and microorganisms and, on the other side, to assure the ...
G. Barbara +7 more
semanticscholar +1 more source
Immuno, 2021 Activation of the nod-like receptor protein 3 (NLRP3) leads to the release of the proinflammatory cytokine IL-1β, which then facilitates pathogen control by macrophages.
Michael Bording-Jorgensen +4 more
doaj +1 more source
Journal of Immunology Research, 2022 Objectives. Intestinal epithelial barrier function is an important mechanical barrier to maintain intestinal homeostasis and resist the invasion of intestinal pathogens and microorganisms.
Yuejin Li +7 more
doaj +1 more source
Epithelial Barrier in the Nasal Mucosa, Related Risk Factors and Diseases
International Archives of Allergy and Immunology, 2023 As the first line of defense against risk factors, the nasal epithelial barrier maintains homeostasis in nasal mucosa. The composition of the epithelial barrier contains physical, chemical, immune, and microbiological barriers.
Rong Zhang +5 more
semanticscholar +1 more source
Allergy Asthma and Immunology Research, 2023 Allergic diseases are a major public health problem with increasing prevalence. These immune-mediated diseases are characterized by defective epithelial barriers, which are explained by the epithelial barrier theory and continuously emerging evidence ...
Purevsuren Losol +15 more
semanticscholar +1 more source
Role of air pollutants in airway epithelial barrier dysfunction in asthma and COPD
European Respiratory Review, 2022 Chronic exposure to environmental pollutants is a major contributor to the development and progression of obstructive airway diseases, including asthma and COPD.
M. Aghapour +6 more
semanticscholar +1 more source