Results 21 to 30 of about 2,478,278 (345)

The relation between age and airway epithelial barrier function

Respiratory Research, 2022
Background The prevalence of age-associated diseases, such as chronic obstructive pulmonary disease (COPD), is increasing as the average life expectancy increases around the world.
M. de Vries, K. O. Nwozor, K. Muizer, M. Wisman, W. Timens, M. van den Berge, A. Faiz, T.-L. Hackett, I. H. Heijink, C. A. Brandsma   +9 more
doaj   +1 more source

How autophagy controls the intestinal epithelial barrier

Autophagy, 2021
Macroautophagy/autophagy is a cellular catabolic process that results in lysosome-mediated recycling of organelles and protein aggregates, as well as the destruction of intracellular pathogens.
E. Foerster, Tapas Mukherjee, Liliane Cabral-Fernandes, J. Rocha, S. Girardin, D. Philpott   +5 more
semanticscholar   +1 more source

Lactic acid from vaginal microbiota enhances cervicovaginal epithelial barrier integrity by promoting tight junction protein expression

Microbiome, 2022
Background Women with a cervicovaginal microbiota dominated by Lactobacillus spp. are at reduced risk of acquiring sexually transmitted infections including HIV, but the biological mechanisms involved remain poorly defined.
D. Delgado-Diaz, Brianna Jesaveluk, Joshua A. Hayward, D. Tyssen, Arghavan Alisoltani, Matthys G. Potgieter, L. Bell, Elizabeth Ross, A. Iranzadeh, Imane Allali, S. Dabee, S. Barnabas, H. Gamieldien, J. Blackburn, Nicola Mulder, Steven B. Smith, V. Edwards, Adam D. Burgener, L. Bekker, J. Ravel, J. Passmore, Lindi Masson, A. Hearps, G. Tachedjian   +23 more
semanticscholar   +1 more source

Mometasone furoate and fluticasone furoate are equally effective in restoring nasal epithelial barrier dysfunction in allergic rhinitis

World Allergy Organization Journal, 2021
Tight junction defects (TJ) have been associated with a defective epithelial barrier function in allergic rhinitis (AR). Intranasal corticosteroids are potent drugs frequently used to treat AR and are shown to restore epithelial integrity by acting on ...
Maria Doulaptsi, Tine Wils, Peter W. Hellings, Katleen Martens, Ricard Farré, Maria Vicario, Wytske Fokkens, Emmanuel Prokopakis, Brecht Steelant   +8 more
doaj   +1 more source

Angiocrine Regulation of Epithelial Barrier Integrity in Inflammatory Bowel Disease

Frontiers in Medicine, 2021
Inflammatory bowel disease describes chronic inflammatory disorders. The incidence of the disease is rising. A major step in disease development is the breakdown of the epithelial cell barrier.
Michael Stürzl, Meik Kunz, Susanne M. Krug, Elisabeth Naschberger   +3 more
doaj   +1 more source

Beneficial autoimmunity at body surfaces – immune surveillance and rapid type 2 immunity regulate tissue homeostasis and cancer [PDF]

, 2014
Epithelial cells line body surface tissues and provide a physicochemical barrier to the external environment. Frequent microbial and non-microbial challenges such as those imposed by mechanical disruption, injury or exposure to noxious environmental ...
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core   +7 more sources

Intestinal epithelial barrier integrity investigated by label-free techniques in ulcerative colitis patients

Scientific Reports, 2023
The intestinal epithelial barrier, among other compartments such as the mucosal immune system, contributes to the maintenance of intestinal homeostasis.
Elsie Quansah, Elena Gardey, Anuradha Ramoji, Tobias Meyer-Zedler, Bianca Goehrig, Astrid Heutelbeck, Stephanie Hoeppener, Michael Schmitt, Maximillian Waldner, Andreas Stallmach, Jürgen Popp   +10 more
doaj   +1 more source

Nasal Epithelial Barrier Integrity and Tight Junctions Disruption in Allergic Rhinitis: Overview and Pathogenic Insights

Frontiers in Immunology, 2021
Allergic rhinitis (AR) is a common disorder affecting up to 40% of the population worldwide and it usually persists throughout life. Nasal epithelial barrier constitutes the first line of defense against invasion of harmful pathogens or aeroallergens ...
Siti Muhamad Nur Husna, H. Tan, Norasnieda binti Md Shukri, N. S. Mohd Ashari, K. Wong   +4 more
semanticscholar   +1 more source

Acinetobacter baumannii Outer Membrane Protein A Induces Pulmonary Epithelial Barrier Dysfunction and Bacterial Translocation Through The TLR2/IQGAP1 Axis

Frontiers in Immunology, 2022
Pulmonary epithelial barrier dysfunction is a critical pathophysiological process in pneumonia and associated invasive infections, such as those caused by Acinetobacter baumannii. However, the mechanisms underlying A.
Wang Zhang, Wang Zhang, Wang Zhang, Hua Zhou, Yan Jiang, Yan Jiang, Yan Jiang, Jintao He, Jintao He, Jintao He, Yue Yao, Yue Yao, Yue Yao, Jianfeng Wang, Xiaochen Liu, Xiaochen Liu, Xiaochen Liu, Sebastian Leptihn, Sebastian Leptihn, Sebastian Leptihn, Xiaoting Hua, Xiaoting Hua, Xiaoting Hua, Yunsong Yu, Yunsong Yu, Yunsong Yu   +25 more
doaj   +1 more source

Antimicrobial peptides: Defending the mucosal epithelial barrier

Frontiers in Oral Health, 2022
The recent epidemic caused by aerosolized SARS-CoV-2 virus illustrates the importance and vulnerability of the mucosal epithelial barrier against infection.
Karen F. Johnstone, M. Herzberg
semanticscholar   +1 more source