Results 281 to 290 of about 921,216 (339)

Endoplasmic reticulum stress and the unfolded protein response in lung diseases: molecular pathways and therapeutic interventions

The Journal of Pathology, EarlyView.
Abstract Endoplasmic reticulum stress (ERS) occurs when the protein‐folding capacity of the endoplasmic reticulum (ER) is overwhelmed, triggering the unfolded protein response (UPR) to restore homeostasis. However, severe or persistent ERS can shift the UPR toward pro‐inflammatory, apoptotic, and fibrotic signaling, thereby exacerbating tissue injury ...
Lanlan Song, Yichen Liu, Chen Xu, Yaochen Zhang, Kaiming Xu, Dan Yao, Xiaoying Huang   +6 more
wiley   +1 more source

Deacetylforskolin ameliorates bleomycin-induced pulmonary fibrosis by suppressing inflammation and TGF-β1-induced epithelial-mesenchymal transition. [PDF]

Nat Prod Bioprospect
Zhong Y, Xiao C, Liang Y, Wang P, Long Y, Li S, Song N, Shang W, Yang W, Zhang X.   +9 more
europepmc   +1 more source

Electroacupuncture modulates gut-lung microbiota and lung EMT to attenuate airway remodeling in COPD. [PDF]

Front Microbiol
Chen D, Zhou Z, Zhou Z, Wang Z, Zhao L, Chen Y.   +5 more
europepmc   +1 more source

Abrine targets ERK to suppress EMT and lung metastasis model via MAPKs and Nrf2/Keap-1/HO-1 signaling. [PDF]

Front Immunol
Shen Y, Xiao L, Liu L, Liao L, Zou X, Shen P, Zhao J, Yuan R, Gao H, Yao C.   +9 more
europepmc   +1 more source

Loss of LLGL1 Elevates EGFR/RAS/MAPK Signaling and Remodels EMT Markers in Huh-7 Hepatocellular Carcinoma Cells. [PDF]

Int J Mol Sci
Yıldız G, Karabulut S, Dincer T, Toraman B.   +3 more
europepmc   +1 more source

E-Cadherin Immunohistochemical Expression in Gastrointestinal Adenocarcinomas and Its Association With Histological and Prognostic Parameters. [PDF]

Cureus
Varadan S, Balasundararajan U, Manoharan D, Mahendran BS.   +3 more
europepmc   +1 more source

Sporadic Hepatocellular Carcinoma in an Adolescent Harboring a Somatic CDH1 Mutation: A Case Report and Literature Review

The Kaohsiung Journal of Medical Sciences, EarlyView.
Chang‐Wei Su, Peir‐In Liang, Shih‐Chang Chuang   +2 more
wiley   +1 more source

Decoding the Molecular Drivers of Epithelial to Mesenchymal Transition in Breast Cancer: Insights into Epithelial Plasticity and Microenvironment Crosstalk. [PDF]

Biology (Basel)
Peri E, Buttacavoli M, Roz E, Pucci-Minafra I, Feo S, Cancemi P.   +5 more
europepmc   +1 more source