Results 291 to 300 of about 921,216 (339)

Distribution and regulation of epithelial cadherin messenger ribonucleic acid and immunocytochemical localization of epithelial cadherin in the rat epididymis.

Endocrinology, 1992
The epithelium of the epididymis possesses an elaborate network of tight junctions between principal cells which is altered as a function of postnatal age. Cadherins are implicated in the formation of tight junctions. The objective of the present study was to determine whether RNA transcripts for cadherins were present in the epididymis, and if so, how
D G, Cyr, L, Hermo, O W, Blaschuk, B, Robaire   +3 more
semanticscholar   +4 more sources

The E-Cadherin and N-Cadherin Switch in Epithelial-to-Mesenchymal Transition: Signaling, Therapeutic Implications, and Challenges

Cells, 2019
Epithelial-to-Mesenchymal Transition (EMT) has been shown to be crucial in tumorigenesis where the EMT program enhances metastasis, chemoresistance and tumor stemness.
Won Fen Wong, Gautam Sethi, Pei Pei Chong   +2 more
exaly   +2 more sources

Epithelial cadherin is present in bovine oviduct epithelial cells and gametes, and is involved in fertilization-related events

Theriogenology, 2014
Fertilization is a calcium-dependent process that involves sequential cell-cell adhesion events of spermatozoa with oviduct epithelial cells (OECs) and with cumulus-oocyte complexes (COCs).
Maria Gracia Gervasi, Silvina Perez-Martinez   +1 more
exaly   +2 more sources

Roles of E-cadherin and Noncoding RNAs in the Epithelial–mesenchymal Transition and Progression in Gastric Cancer

International Journal of Molecular Sciences, 2019
The epithelial–mesenchymal transition (EMT) is thought to be at the root of invasive and metastatic cancer cell spreading. E-cadherin is an important player in this process, which forms the structures that establish and maintain cell–cell interactions. A
Marina V Nemtsova, Dmitry Zaletaev
exaly   +2 more sources

The basics of epithelial–mesenchymal transition (EMT): A study from a structure, dynamics, and functional perspective

Journal of Cellular Physiology, 2019
Epithelial–mesenchymal transition (EMT) is a key step in transdifferentiation process in solid cancer development. Forthcoming evidence suggest that the stratified program transforms polarized, immotile epithelial cells to migratory mesenchymal cells ...
Vishal Das, Sourya Bhattacharya, Channakeshavaiah Chikkaputtaiah, Saugata Hazra, Mintu Pal   +4 more
semanticscholar   +1 more source

Epithelioid sarcoma: presence of vascular‐endothelial cadherin and lack of epithelial cadherin

Histopathology, 1998
AimsTo evaluate the pattern of cadherin expression in epithelioid sarcoma.Methods and resultsSeven epithelioid sarcomas were immunostained by a polyclonal antibody that detects all cadherin subtypes and by monoclonal antibodies that detect epithelial cadherin (E‐cadherin) and vascular‐endothelial cadherin (VE cadherin).
M E, Smith, J I, Brown, C, Fisher
openaire   +2 more sources

Thermodynamic Stability of Domain 2 of Epithelial Cadherin

Biochemistry, 2004
Cadherin is a cell adhesion molecule that participates in ordered calcium-dependent self-association interactions both between molecules on the same cell surface (cis-interactions) and on neighboring cell surfaces (trans-interactions). Cadherin is a transmembrane protein that has 3-7 independently folded beta-barrel extracellular domains. Both types of
Alka, Prasad, Nicole A, Housley, Susan, Pedigo   +2 more
openaire   +2 more sources

Cadherins and Epithelial-to-Mesenchymal Transition

2013
Epithelial-mesenchymal transition (EMT) is a process whereby epithelial cells are transcriptionally reprogrammed, resulting in decreased adhesion and enhanced migration or invasion. EMT occurs during different stages of embryonic development, including gastrulation and neural crest cell delamination, and is induced by a panel of specific transcription ...
Alexander, Gheldof, Geert, Berx
openaire   +2 more sources

Epithelial Paradox: Clinical Significance of Coexpression of E‐cadherin and Vimentin With Regard to Invasion and Metastasis of Breast Cancer

Clinical Breast Cancer, 2018
Background E‐cadherin and vimentin are regarded as major conventional canonical markers of the epithelial–mesenchymal transition. It is commonly assumed that E‐cadherin is uniformly lost during the process of epithelial–mesenchymal transition.
N. Yamashita, E. Tokunaga, M. Iimori, Y. Inoue, Kimihiro Tanaka, H. Kitao, H. Saeki, E. Oki, Y. Maehara   +8 more
semanticscholar   +1 more source