Results 71 to 80 of about 195,613 (192)
Frontiers in Immunology, 2018 Dendritic cell (DC) expression of CD103, the α subunit of αEβ7 integrin, is thought to enable DC interactions with E-cadherin-expressing gastrointestinal epithelia for improved mucosal immunosurveillance.
Steve Swain +8 more
doaj +1 more source
WAVE2 regulates epithelial morphology and cadherin isoform switching through regulation of Twist and Abl. [PDF]
PLoS ONE, 2013 Epithelial morphogenesis is a dynamic process that involves coordination of signaling and actin cytoskeletal rearrangements.We analyzed the contribution of the branched actin regulator WAVE2 in the development of 3-dimensional (3D) epithelial structures.
Nicole S Bryce +3 more
doaj +1 more source
miR-200c sensitizes breast cancer cells to doxorubicin treatment by decreasing TrkB and Bmi1 expression. [PDF]
, 2012 Acquired resistance to classical chemotherapeutics is a major obstacle in cancer treatment. Doxorubicin is frequently used in breast cancer therapy either as single-agent or in combination with other drugs like docetaxel and cyclophosphamide.
Kopp, Florian +3 more
core +3 more sources
Truncated E‐cadherin potentiates cell death in prostate epithelial cells [PDF]
The Prostate, 2005 AbstractBACKGROUNDE‐cadherin, a fundamental component of the adherens junction, is known to mediate aggregation‐dependent cell survival. We have previously identified a novel, calpain‐dependent proteolytic cleavage of E‐cadherin that resulted in the generation of a stable 100‐kDa E‐cadherin fragment (E‐cad100) in prostate epithelial cells in response ...
Rios-Doria, Jonathan, Day, Mark L.
openaire +3 more sources
Clostridium perfringens Delta-Toxin Damages the Mouse Small Intestine
Toxins, 2019 Clostridium perfringens strains B and C cause fatal intestinal diseases in animals. The secreted pore-forming toxin delta-toxin is one of the virulence factors of the strains, but the mechanism of intestinal pathogenesis is unclear. Here, we investigated
Soshi Seike +3 more
doaj +1 more source
Clinical Epidemiology and Global Health, 2023 Objectives: Endometrial carcinoma (EC), majority being endometroid endometrial carcinoma (EEC), is the most common invasive gynecological cancer world-wide.
Sunita Yadav +5 more
doaj +1 more source
Patterns in Space: Coordinating Adhesion and Actomyosin Contractility at E-cadherin Junctions
, 2013 Cadherin adhesion receptors are fundamental determinants of tissue organization in health and disease. Increasingly, we have come to appreciate that classical cadherins exert their biological actions through active cooperation with the contractile actin ...
Wu, Selwin K., Yap, Alpha S.
core +1 more source
PRL-3 promotes epithelial mesenchymal transition by regulating cadherin directly [PDF]
Cancer Biology & Therapy, 2009 PRL-3 is a key gene associated with progression and metastasis of colorectal cancer. Recently PRL-3 was suggested to promote epithelial mesenchymal transition (EMT) by downregulating E-cadherin expression. But the mechanisms of EMT induced by PRL-3 remain largely unknown. Here we found that PRL-3 could also promote EMT in a colorectal cancer cell model
Yuhong, Liu +6 more
openaire +2 more sources
P-Cadherin Expression in Feline Mammary Tissues
Veterinary Medicine International, 2012 The search for molecular markers in the feline mammary gland, namely, the adhesion molecules belonging to the cadherin family, is useful in the understanding of the development of mammary carcinomas in felines and humans.
Ana Catarina Figueira +5 more
doaj +1 more source
Oncology Reviews, 2020 The metastatic process of ovarian cancer (OC) is almost exclusively defined by direct shedding of tumor cells into the abdominal cavity, followed by clustering into multicellular aggregates and posterior peritoneal anchorage.
Ricardo J. Roque +2 more
doaj +1 more source