Results 221 to 230 of about 395,501 (352)

Targeting Splenic Myeloid Cells with Nanobiologics to Prevent Postablative Pancreatic Cancer Recurrence via Inducing Antitumor Peripheral Trained Immunity

Advanced Science, EarlyView.
Using a preclinical pancreatic cancer model, we identified that tumor progression restructures splenic immunity via myeloid cell expansion. MDCa@RBC‐Alipo nanobiologics were engineered to epigenetically and metabolically reprogram splenic myeloid cells, alleviating post‐ablation immunosuppression.
Shengbo Wu, Weichen Xu, Xuexia Shan, Liping Sun, Shuo Liu, Xixi Sun, Shaoyue Li, Xiaodong Hou, Xiaowan Bo, Chengzhong Peng, Bin Huang, Huixiong Xu, Wenwen Yue   +12 more
wiley   +1 more source

Isolation Techniques of Micro/Nano‐Scaled Species for Biomedical Applications

Advanced Science, EarlyView.
Separating micro/nano‐scale bioparticles from samples is essential for disease diagnosis, prevention, and monitoring. Therefore, a comprehensive overview of the latest advanced separation technologies is provided, and characteristics and limitations based on six key performance parameters, including purity, recovery rate, throughput, resolution, size ...
Qing Lu, Zhinan Zhang, Xianting Ding
wiley   +1 more source

Identification of Dominant Optimal HLA-B60- and HLA-B61-Restricted Cytotoxic T-Lymphocyte (CTL) Epitopes: Rapid Characterization of CTL Responses by Enzyme-Linked Immunospot Assay

Journal of Virology, 2000
M. Altfeld, A. Trocha, Robert L. Eldridge, E. Rosenberg, M. N. Phillips, M. Addo, R. Sékaly, S. Kalams, Sandra A. Burchett, K. Mcintosh, B. Walker, P. Goulder   +11 more
semanticscholar   +1 more source

Tailoring a Functional Synthetic Microbial Community Alleviates Fusobacterium nucleatum‐infected Colorectal Cancer via Ecological Control

Advanced Science, EarlyView.
The bottom‐up strategy based on multiomics data is used for the SynCom design, and it successfully inhibited F. nucleatum growth and achieved stable colonization in vivo. In addition, it promoted tryptophan metabolism and secondary bile acid conversion, reduced lipid accumulation, relieved microbiome disorder, decreased inflammatory reaction, and ...
Zhongkun Zhou, Mengyue Yang, Hong Fang, Baizhuo Zhang, Yunhao Ma, Yongyuan Li, Yingjie Liu, Zeying Cheng, Yuanchun Zhao, Zhenzhen Si, Hongmei Zhu, Peng Chen   +11 more
wiley   +1 more source

In Silico Design, Optimization, and Evaluation of a Multi-Epitope Vaccine Targeting the <i>Clostridium perfringens</i> Collagen Adhesin Protein. [PDF]

Microorganisms
Chundru D, Bhattrai S, Timilsina M, Lillehoj H, Sun Z, Ghanem M, Li C.   +6 more
europepmc   +1 more source

Quantitation of CD8+ T-Lymphocyte Responses to Multiple Epitopes from Simian Virus 40 (SV40) Large T Antigen in C57BL/6 Mice Immunized with SV40, SV40 T-Antigen-Transformed Cells, or Vaccinia Virus Recombinants Expressing Full-Length T Antigen or Epitope Minigenes

Journal of Virology, 2000
L. Mylin, T. Schell, Debra Roberts, M. Epler, A. Boesteanu, E. Collins, J. Frelinger, S. Joyce, S. Tevethia   +8 more
semanticscholar   +1 more source

A Porphyrin Nanomaterial for Photoimmunotherapy for Treatment of Melanoma

Advanced Science, EarlyView.
The TPC@OVA NPs are developed as dual‐functional nanomaterials combining phototherapy and immunotherapy for melanoma treatment. This system effectively ablates primary tumors, induces immunogenic cell death, promotes dendritic cell maturation, and enhances T cell activation.
Zhuang Fan, Qing Pei, Haojie Sun, Haiyan Zhang, Zhigang Xie, Tao Zhang, Chong Ma   +6 more
wiley   +1 more source

Immunoinformatics method to design universal multi-epitope nanoparticle vaccine for TGEV S protein. [PDF]

Sci Rep
Li S, Yu J, Xiao C, Li Y.
europepmc   +1 more source

Development of a novel multi-epitope vaccine for brucellosis prevention

Heliyon
Brucellosis, a zoonotic disease caused by Brucella, presents a significant threat to both animal and human health. In animals, the disease can lead to infertility, miscarriage, and high fever, while in humans, symptoms may include recurrent fever ...
Kaiyu Shang, Yuejie Zhu, Tingting Tian, Huidong Shi, Zhengwei Yin, Yueyue He, Juan Shi, Jianbing Ding, Fengbo Zhang   +8 more
doaj  

Elicitation of High-Frequency Cytotoxic T-Lymphocyte Responses against both Dominant and Subdominant Simian-Human Immunodeficiency Virus Epitopes by DNA Vaccination of Rhesus Monkeys

Journal of Virology, 2001
D. Barouch, A. Craiu, S. Santra, M. Egan, J. Schmitz, M. Kuroda, T. Fu, J. Nam, L. Wyatt, M. Lifton, G. Krivulka, C. E. Nickerson, C. I. Lord, B. Moss, M. Lewis, V. Hirsch, J. Shiver, N. Letvin   +17 more
semanticscholar   +1 more source