Results 81 to 90 of about 15,072 (244)

Assessment of Quality of Care Provided for Patients Receiving Post‐Myocardial Infarction Care at Selected Cardiac Clinics in Sulaymaniyah: Cross‐Sectional Study

Health Science Reports, Volume 9, Issue 3, March 2026.
ABSTRACT Background According to global projections, by the year 2050, ischemic heart disease will remain the leading cause of cardiovascular deaths with hypertension as a leading modifiable risk factor for mortality. Improving quality care for patients with acute myocardial infarction (MI) is associated with improved outcomes. Aims There is inadequate
Banaz Sadiq Elias, Yara Sarwar Hamid, Mende Mensa Sorato   +2 more
wiley   +1 more source

Development of a High‐Risk Medication List for Australian Residential Aged Care: A Modified Delphi Study

Australasian Journal on Ageing, Volume 45, Issue 1, March 2026.
ABSTRACT Introduction High‐risk medications are medications associated with significant patient harm or death if misused or used in error. This study aimed to develop a national consensus high‐risk medication list for use in Australian residential aged care.
Amanda J. Cross, Madiha Chaudhry, Darshna Goordeen, Juanita L. Breen, Malcolm Clark, Stephanie Daly, Belinda Delardes, Bente Hart, Deborah Hawthorne, Peter J. Hayball, Sarah N. Hilmer, Lisa Kouladjian O’Donnell, MaryAnn Kulh, Kenneth Lee, David F. L. Liew, Stephen Macfarlane, Elizabeth Manias, Anthony Marinucci, Constance Dimity Pond, Helen Rawson, Susan Slatyer, Andrew Stafford, Amy B. Thomson, Kate Wang, Kirolos Wasef, Jonathan Zimmerman, Nadine E. Andrew, Gauri P. Godbole, Louise Lord, Atish Manek, Brigid McInerney, Michelle Steeper, Justin P. Turner, J. Simon Bell   +33 more
wiley   +1 more source

Cost-Effectiveness of Eplerenone in Patients with Left Ventricular Dysfunction after Myocardial Infarction—An Analysis of the EPHESUS Study from a Swiss Perspective [PDF]

, 2018
Objective: The EPHESUS study demonstrated that aldosterone blockade with eplerenone decreased mortality in patients with left ventricular systolic dysfunction (LVSD) and heart failure after acute myocardial infarction (AMI).
Burnier, Michel, Erne, Paul, Holm, Majbrit, Schwenkglenks, Matthias, Szucs, Thomas, Weintraub, William, Zhang, Zefeng   +6 more
core  

Contribution of Endogenous Glucocorticoids and Their Intravascular Metabolism by 11β-HSDs to Postangioplasty Neointimal Proliferation in Mice [PDF]

, 2012
Exogenous glucocorticoids inhibit neointimal proliferation in animals. We aime to test the hypothesis that endogenous glucocorticoids influence neointimal proliferation; this may be mediated by effects on systemic risk factors or locally in vessels, and ...
Hadoke, Patrick W. F., Iqbal, Javaid, Low, Lucinda, Macdonald, Linsay J., Seckl, Jonathan R., Walker, Brian R., Yau, Christopher W.   +6 more
core   +1 more source

Stabilization of Early Duchenne Cardiomyopathy With Aldosterone Inhibition: Results of the Multicenter AIDMD Trial

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2019
Background Duchenne muscular dystrophy incurs nearly universal dilated cardiomyopathy by the third decade of life, preceded by myocardial damage and impaired left ventricular strain by cardiac magnetic resonance.
Subha V. Raman, Kan N. Hor, Wojciech Mazur, Andrea Cardona, Xin He, Nancy Halnon, Larry Markham, Jonathan H. Soslow, Michael D. Puchalski, Scott R. Auerbach, Uyen Truong, Suzanne Smart, Beth McCarthy, Ibrahim M. Saeed, Jeffrey M. Statland, John T. Kissel, Linda H. Cripe   +16 more
doaj   +1 more source

Managing High‐Risk Drug Interactions With Nirmatrelvir/Ritonavir: Experience From a Dedicated Pharmacology Advice Service

Clinical and Translational Science, Volume 19, Issue 3, March 2026.
ABSTRACT Nirmatrelvir boosted with ritonavir is a key antiviral against COVID‐19, yet ritonavir's potent CYP3A4 inhibition exposes patients to numerous drug–drug interactions. To make prescribing safer, a national proactive system providing expert pharmacology advice was implemented in France.
Youssef Libiad, Bénédicte Franck, Camille Tron, Sébastien Lalanne, Christelle Boglione‐Kerrien, Fabrice Taïeb, Marie‐Clémence Verdier, Florian Lemaitre   +7 more
wiley   +1 more source

Type of atrial fibrillation and clinical outcomes in patients with heart failure and reduced ejection fraction [PDF]

, 2017
Background: Atrial fibrillation (AF) is common in heart failure (HF), but the outcome by type of AF is largely unknown. Objectives: This study investigated outcomes related to type of AF (paroxysmal, persistent or permanent, or new onset) in 2 ...
Abraham, William T., Desai, Akshay S., Dickstein, Kenneth, Jhund, Pardeep S., Køber, Lars, McMurray, John J.V., Mogensen, Ulrik M., Packer, Milton, Rouleau, Jean L., Solomon, Scott D., Swedberg, Karl, Zile, Michael R.   +11 more
core   +3 more sources

Six‐Year Trends in Real‐World Data Use for Post‐Marketing Surveillance of New Medical Products in Japan

Clinical and Translational Science, Volume 19, Issue 2, February 2026.
ABSTRACT The Ministerial Ordinance on Good Post‐Marketing Study Practice for Drugs was amended by the Ministry of Health, Labour and Welfare (MHLW) in 2018 to clearly define post‐marketing database studies (DBS) as a measure of pharmacovigilance activities for approved medical products in Japan.
Suguru Okami, Kako Shimotsumagari, Yasunari Sadatsuki   +2 more
wiley   +1 more source

Eplerenone attenuates pathological pulmonary vascular rather than right ventricular remodeling in pulmonary arterial hypertension [PDF]

, 2018
BACKGROUND: Aldosterone is a mineralocorticoid hormone critically involved in arterial blood pressure regulation. Although pharmacological aldosterone antagonism reduces mortality and morbidity among patients with severe left-sided heart failure, the ...
Arnold, N., Boehm, M., Braithwaite, A., Ghofrani, H.A., Grimminger, F., Kiely, D.G., Kojonazarov, B., Lawrie, A., Lu, C., Novoyatleva, T., Pickworth, J., Schermuly, R.T., Seeger, W., Weissmann, N.   +13 more
core   +1 more source

The biology of PKM2 in the metabolism and senescence in diabetic kidney disease

Journal of Diabetes Investigation, Volume 17, Issue 2, Page 197-204, February 2026.
ABSTRACT Diabetic kidney disease (DKD) is one of the most common causes of chronic kidney disease that leads to end‐stage kidney disease, and its progression is closely linked to metabolic stress within renal tubular cells. Under long‐term hyperglycemia, cells shift their glucose metabolism from normal oxidative phosphorylation toward glycolysis.
Md. Imrul Kayes, Keizo Kanasaki
wiley   +1 more source