Results 81 to 90 of about 14,810 (242)

Transfemoral Transcatheter Aortic Valve Implantation (TF‐TAVI) for Patients With Left Ventricular Assist Device (LVAD) and Aortic Regurgitation

Catheterization and Cardiovascular Interventions, Volume 106, Issue 7, Page 3473-3480, December 1, 2025.
ABSTRACT Aortic regurgitation (AR) develops in up to 25%−30% of patients with left ventricular assist device (LVAD). Treatment remains challenging since surgery confers significant peri‐operative risk and the lack of valvular calcification renders transfemoral transcatheter aortic valve implantation (TF‐TAVI) with non‐dedicated devices technically ...
Daniel Tai‐Leung Chan, Ho‐On Alston Conrad Chiu, Ka‐Lam Wong, Ka‐Chun Un, Kwong‐Yue Eric Chan, Shu‐Yue Sze, Chor‐Cheung Frankie Tam, On‐Yat Wong, Gilbert H. L. Tang, Simon Cheung‐Chi Lam   +9 more
wiley   +1 more source

Inflammation and genetics in myo‐pericardial diseases: Insights from the Italian Study Group on Cardiomyopathies and Pericardial Diseases

ESC Heart Failure, Volume 12, Issue 6, Page 3987-3999, December 2025.
Proposed management of myo‐pericardial diseases. A systematic interdisciplinary approach to myo‐pericardial disease is essential to reach a correct diagnosis, starting from multiparametric characterization including EKG, echocardiography with GLS, laboratory exams and CMR or, in case of electric or haemodynamic instability, EMB.
Marco Merlo, Giulia Bassetto, Antonio Cannatà, Alberto Aimo, Camillo Autore, Barbara Bauce, Elena Biagini, Francesco Cappelli, Silvia Castelletti, Flavio D'Ascenzi, Cesare de Gregorio, Giuseppe Limongelli, Francesca Marzo, Beatrice Musumeci, Giacomo Tini, Roberto Pedrinelli, Pasquale Perrone Filardi, Gianfranco Sinagra, Massimo Imazio   +18 more
wiley   +1 more source

Eplerenone inhibits aldosterone-induced CRP generation in rat vascular smooth muscle cells by regulating the MR-ROS-ERK1/2 signal pathway

European Journal of Inflammation, 2017
Atherosclerosis is a chronic inflammatory disease in the vessel wall. As a representative inflammatory cytokine, C-reactive protein (CRP) participates in the formation and development of atherosclerosis.
Xiaolu Zhang, Juntian Liu, Xiaoming Pang, Jingjing Zhao, Shouzhu Xu, Jing Zhao   +5 more
doaj   +1 more source

Early in‐hospital treatment of acute heart failure. Part 2 of the international expert opinion series on AHF management

ESC Heart Failure, Volume 12, Issue 6, Page 3826-3843, December 2025.
This state‐of‐the‐art review outlines a practical, evidence‐based framework for early acute heart failure management to address critical gaps in current guidance and improve early treatment outcomes. Key components include early identification of co‐existing conditions, bedside haemodynamic profiling, a structured diagnostic approach incorporating both
Anika S. Naidu, Andrew P. Ambrosy, Gad Cotter, Edimar A. Bocchi, Javed Butler, Ovidiu Chioncel, Beth Davison, Anastase Dzudie, Yonathan Freund, Marat Fudim, Sivadasanpillai Harikrishnan, Ivna G. Cunha, Alexandre Mebazaa, Robert J. Mentz, Òscar Miró, Siti E. Nauli, Mateo Pagnesi, Naoki Sato, Gianluigi Savarese, Karen Sliwa‐Hahnle, Yuhui Zhang, Jingmin Zhou, Jan Biegus   +22 more
wiley   +1 more source

Stabilization of Early Duchenne Cardiomyopathy With Aldosterone Inhibition: Results of the Multicenter AIDMD Trial

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2019
Background Duchenne muscular dystrophy incurs nearly universal dilated cardiomyopathy by the third decade of life, preceded by myocardial damage and impaired left ventricular strain by cardiac magnetic resonance.
Subha V. Raman, Kan N. Hor, Wojciech Mazur, Andrea Cardona, Xin He, Nancy Halnon, Larry Markham, Jonathan H. Soslow, Michael D. Puchalski, Scott R. Auerbach, Uyen Truong, Suzanne Smart, Beth McCarthy, Ibrahim M. Saeed, Jeffrey M. Statland, John T. Kissel, Linda H. Cripe   +16 more
doaj   +1 more source

Finerenone in diabetic chronic kidney disease—Real‐world insights including patients with HFpEF or HFmrEF

ESC Heart Failure, Volume 12, Issue 6, Page 4219-4229, December 2025.
Abstract Purpose Finerenone, a highly selective non‐steroidal mineralocorticoid receptor antagonist, was approved for the treatment of patients with chronic kidney disease (CKD) and type 2 diabetes mellitus (diabetic kidney disease, DKD). Finerenone reduced the composite endpoint of heart failure events and cardiovascular death in patients with heart ...
Kristian Hellenkamp, Sophia Kaebe, Miroslava Valentova, Stephan von Haehling, Fani Delistefani, Katja Gollisch, Dirk Raddatz, Ann‐Kathrin Schäfer, Michael J. Koziolek, Manuel Wallbach   +9 more
wiley   +1 more source

Epidermal mineralocorticoid receptor plays beneficial and adverse effects in skin and mediates glucocorticoid responses [PDF]

, 2016
10 páginas, 6 figuras. Contiene material suplementarioGlucocorticoids (GCs) regulate skin homeostasis and combat cutaneous inflammatory diseases; however, adverse effects of chronic GC treatments limit their therapeutic use.
Boix, Julia, Carceller, Elena, Pérez, Paloma, Sevilla, Lisa M., Sáez, Zara   +4 more
core   +1 more source

Machine learning approach to identify phenotypes in patients with ischaemic heart failure with reduced ejection fraction

European Journal of Heart Failure, Volume 27, Issue 12, Page 3378-3391, December 2025.
Summary of the machine learning clustering methodology and results of the study. Clusters are identified using machine learning approach in the learning set population evaluating specific combinations of multiple characteristics. Then identified clusters are predicted and tested in the learning set to evaluate their association with outcomes.
Luca Monzo, Emmanuel Bresso, Kenneth Dickstein, Bertram Pitt, John G.F. Cleland, Stefan D. Anker, Carolyn S.P. Lam, Mandeep R. Mehra, Dirk J. van Veldhuisen, Barry Greenberg, Faiez Zannad, Nicolas Girerd   +11 more
wiley   +1 more source

Hypokalemic rhabdomyolysis: a rare manifestation of primary aldosteronism [PDF]

, 2015
Rhabdomyolysis is a rare presentation of hypokalemia, although muscle weakness is a well-known manifestation of hypokalemia. Primary aldosteronism is characterized by hypertension, suppressed plasma renin activity, increased aldosterone excretion and ...
CONCISTRE, ANTONIO, FIACCO, FEDERICA, LETIZIA, Claudio, MARINELLI, CRISTIANO, MITTERHOFER, Anna Paola, PETRAMALA, LUIGI, TINTI, FRANCESCA, UMBRO, ILARIA, ZAVATTO, ASSUNTA, ZINGARETTI, VIVIANA   +9 more
core  

Contribution of Endogenous Glucocorticoids and Their Intravascular Metabolism by 11β-HSDs to Postangioplasty Neointimal Proliferation in Mice [PDF]

, 2012
Exogenous glucocorticoids inhibit neointimal proliferation in animals. We aime to test the hypothesis that endogenous glucocorticoids influence neointimal proliferation; this may be mediated by effects on systemic risk factors or locally in vessels, and ...
Hadoke, Patrick W. F., Iqbal, Javaid, Low, Lucinda, Macdonald, Linsay J., Seckl, Jonathan R., Walker, Brian R., Yau, Christopher W.   +6 more
core   +1 more source