Results 81 to 90 of about 14,325 (202)
Present and future pharmacotherapeutic agents in heart failure: an evolving paradigm [PDF]
, 2016 Many conditions culminate in heart failure (HF), a multi-organ systemic syndrome with an intrinsically poor prognosis. Pharmacotherapeutic agents that correct neurohormonal dysregulation and haemodynamic instability have occupied the forefront of ...Abozguia, AIRE Study Group, Alexander, Alexander, Alexander, Alexander, Ashrafian, Bailey, Bailey, Basu, Beadle, Braunwald, Brown, Burgoyne, Chaitman, Chatterjee, Chung, CIBIS-II Study Group, Cleland, Clerc, Cohn, Cohn, Cohn, CONSENSUS Trial Study Group, Conway, Cook, Dai, Digitalis Investigation Group, Doenst, Dzau, Dzau, Faris, Flather, Follath, Foster, Fox, Fox, Fragasso, Furberg, Gheorghiade, Gladwin, Goffart, Granger, Greenberg, Guazzi, Guazzi, Heymans, Hobbs, Holubarsch, Horowitz, Horowitz, Kantor, Kapil, Kato, Kennedy, Kennedy, Kostis, Larsen, Lee, Lopaschuk, Luiken, Lundberg, Maher, Maier, Mancini, Mann, Mann, Massie, Mccormack, Mcdowell, Mcmurray, Mcmurray, Merit-Hf Study Group, Munzel, Munzel, Neglia, Neubauer, Ormerod, Packer, Packer, Paul, Pawson, Pfeffer, Pfeffer, Pitt, Pitt, Rathore, Rauchhaus, Redfield, Rona, Sack, Sarraf, Schmidt-Schweda, Schrauwen, Schwarz, Shah, Shah, Siddiqi, Singh, SOLVD Investigators, Stanley, Swedberg, Szwed, Taylor, Teerlink, Tilemann, Torre-Amione, Totzeck, Turcani, Unger, Van Der Vusse, Van Faassen, Vardeny, Webb, Yin, Yusuf, Zamani, Zannad, Zannad, Zhang +119 morecore +1 more sourceAn individual treatment effect approach to predict response to mineralocorticoid receptor antagonists in patients with heart failure and reduced ejection fraction
European Journal of Heart Failure, EarlyView.Aims
Mineralocorticoid receptor antagonists (MRAs) are often underused in patients with heart failure (HF) and reduced ejection fraction (HFrEF). Individual treatment effect (ITE) may assist physicians in making timely decisions about which patients are the best suited for personalized therapy.Masatake Kobayashi, Kevin Duarte, João Pedro Ferreira, Guillaume Baudry, Luca Monzo, John J.V. McMurray, Dirk J Van Veldhuisen, Bertram Pitt, Faiez Zannad, Nicolas Girerd +9 morewiley +1 more sourceEuropean Journal of Heart Failure consensus statement. Heart failure pharmacotherapy for patients with heart failure with reduced ejection fraction and concomitant atrial fibrillation: Review of evidence and call to action
European Journal of Heart Failure, EarlyView.Heart failure (HF) and atrial fibrillation (AF) are major global health challenges with rising prevalence and significant morbidity, mortality, and healthcare burden. Despite advances in HF management, AF remains a critical comorbidity that worsens outcomes and requires ad hoc treatment strategies, increasing the risk of non‐adherence and side effects. Mark Luedde, Stefan Agewall, Giuseppe Ambrosio, Antoni Bayes‐Genis, Claudio Borghi, Elisabetta Cerbai, Gheorghe A. Dan, Heinz Drexel, Péter Ferdinandy, Erik Lerkevang Grove, Juan Carlos Kaski, Roland Klingenberg, Joao Morais, William Parker, Mark C. Petrie, Bianca Rocca, Anne Grete Semb, Michele Senni, Christian Sohns, Patrick Sulzgruber, Juan Tamargo, Marco Metra, Michael Böhm, Dobromir Dobrev, Samuel Sossalla +24 morewiley +1 more sourceUrinary markers in heart failure – types, timing and thresholds. European Journal of Heart Failure expert consensus document
European Journal of Heart Failure, EarlyView.Pathophysiologic mechanisms of heart failure (HF) (i.e. renin–angiotensin–aldosterone system [RAAS], congestion, and inflammation), together with patient‐related factors such as diabetes, hypertension, and chronic kidney disease (CKD), contribute to kidney function decline and glomerular or tubular injury.Masatake Kobayashi, Biykem Bozkurt, Peder Langeland Myhre, Juan Carlos Lopez Azor, Mateusz Guzik, Gracjan Iwanek, Guillaume Baudry, Marta Cobo‐Marcos, Òscar Miró, Jeroen Dauw, Piotr Ponikowski, Wilfried Mullens, Alberto Palazzuoli, Marco Metra, Jan Biegus +14 morewiley +1 more sourceEplerenone improves kidney function and cardiac performance in obese male mice
Diabetic Medicine, EarlyView.Abstract Aims
Renin‐angiotensin‐aldosterone system (RAAS) activation mediates obesity‐associated cardiorenal dysfunction. Due to an incomplete understanding of the molecular mechanisms, the clinical use of RAAS antagonism in obesity‐associated cardiometabolic complications remains uncertain.Ayman K. Banah, Bingxue Qi, Ryan Koh, Alexander Lawlor, Tianzhen Wang, Vishal Musale, Joanne Mains, Colin E. Murdoch, Li Kang +8 morewiley +1 more sourceTreatment of Heart Failure with Preserved Ejection Fraction [PDF]
, 2011 Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/90240/1/phco.31.3.312 ...Barnes, Megan M., Bleske, Barry E., Dorsch, Michael P., Hummel, Scott L., Koelling, Todd M. +4 morecore +1 more sourceCo‐Occurrence of Endogenous and Exogenous Cushing's Syndromes: Does “Double Cushing Syndrome” Really Exist? A Case Report
Clinical Case Reports, Volume 13, Issue 11, November 2025.ABSTRACT
Double Cushing syndrome exists: exogenous steroid use can mask concurrent adrenal hypercortisolism. When symptoms persist and cortisol remains high after tapering or stopping prescribed glucocorticoids, an endogenous source is likely. Early recognition with ACTH testing, dexamethasone suppression, and adrenal imaging reduces misdiagnosis ...Reza Amani‐Beni, Atiyeh Karimi Shervedani, Bahar Darouei, Matin Noroozi, Maryam Heidarpour +4 morewiley +1 more sourceEndothelial Dysfunction in Human Essential Hypertension [PDF]
, 2016 Although the endothelium has a number of important functions, the term endothelial dysfunction is commonly used to describe impairment in its vasodilatory capacity.Akiyama, Alexander, Anderson, Antony, Benjamin, Blanco-Rivero, Brehm, Brundtland, Cardillo, Cardillo, Ceconi, Celermajer, Charakida, Charakida, Cockcroft, Corretti, Corretti, Creager, Dawes, Deanfield, Dell’Omo, Deng, Dorresteijn, Dzau, d’Uscio, Erdos, Ergul, Fargin, Farquharson, Fischer, Flammer, Forstermann, Frielingsdorf, Fujimura, Furchgott, Gao, Garnier, Gaziano, Ghiadoni, Ghiadoni, Ghiadoni, Gokce, Gryglewski, Halcox, Hamburg, Haynes, Higashi, Hirooka, Hornig, Imai, Joannides, Juonala, Karthikeyan, Kerth, Kielstein, Kiowski, Klingbeil, Kobayashi, Koh, Kohno, Korkmaz, Krum, Kuvin, Lawes, Linder, Ludmer, Luscher, Luscher, Lyons, Mancia, Mancini, Millgard, Millgard, Modena, Morimoto, Muiesan, Muiesan, Murad, Nakamura, Nitenberg, Panza, Panza, Panza, Park, Pasini, Peller, Perticone, Perticone, Reriani, Rizzoni, Rizzoni, Romero, Rossi, Rossi, Roustit, Roustit, Rubanyi, Rubanyi, Russell, Savoia, Schiffrin, Schiffrin, Schiffrin, Schiffrin, Schiffrin, Schiffrin, Siegrist, Siragy, Suwaidi, Suzuki, Taddei, Taddei, Taddei, Taddei, Taddei, Takiguchi, Tiryaki, Troost, Turner, Tzemos, Tzemos, Ullian, van Hecke, Vanhoutte, Vinereanu, Virdis, Virdis, Vitale, Wagner, Weil, Wilkinson, Wood, Yamanari, Yanagisawa, Yavuz, Yilmaz, Zhang, Zhou +137 morecore +3 more sources