Results 121 to 130 of about 11,968 (183)

Novel Soluble Epoxide Hydrolase Inhibitor: Toward Regulatory Preclinical Studies. [PDF]

ACS Pharmacol Transl Sci
Jarne-Ferrer J, Sánchez J, Codony S, Schneider M, Müller CE, Sanfeliu C, Franco R, Vazquez S, Griñán-Ferré C, Pallàs M.   +9 more
europepmc   +1 more source

Hepatocyte-Specific Transcriptional Responses to Liver-Targeted Delivery of a Soluble Epoxide Hydrolase Inhibitor in a Mouse Model of Alcohol-Associated Liver Disease. [PDF]

Biology (Basel)
Warner DR, Warner JB, Hardesty JE, Abdelfadil Y, Soni C, Bauer P, Maldonado C, McClain CJ, Kirpich IA.   +8 more
europepmc   +1 more source

The soluble epoxide hydrolase inhibitor TPPU alleviates Aβ-mediated neuroinflammatory responses in Drosophila melanogaster and cellular models of alzheimer's disease. [PDF]

J Inflamm (Lond)
Sun X, Liu H, Li W, Li L, Tian Q, Cao Q, Meng Y, Shen Y, Che F, Chiu JC, Yu J, Hammock BD.   +11 more
europepmc   +1 more source

Inhibition of soluble epoxide hydrolase confers neuroprotection and restores microglial homeostasis in a tauopathy mouse model. [PDF]

Mol Neurodegener
Wang S, Qi C, Rajpurohit C, Ghosh B, Xiong W, Wang B, Qi Y, Hwang SH, Hammock BD, Li H, Gan L, Zheng H.   +11 more
europepmc   +1 more source

Metabolic and vascular contributions to dementia: Soluble epoxide hydrolase-derived linoleic acid oxylipins and glycemic status are related to cerebral small vessel disease markers, atrophy, and cognitive performance. [PDF]

Alzheimers Dement
Ryoo SW, Lin WZ, Magliocco A, Ruthirakuhan M, Wong YY, Perfetto SE, Huang C, Anita NZ, Arnott SR, Lang AE, Symons S, Hegele RA, Goubran M, Ramirez J, Ottoy J, Rabin JS, MacIntosh BJ, Lanctôt KL, Liang N, Cogo-Moreira H, Taha AY, Swardfager W, ONDRI Investigators.   +22 more
europepmc   +1 more source

Indole Alkaloids and Phenolic Amides from the Rhizomes of <i>Cimicifuga heracleifolia</i> and Their In Vitro Soluble Epoxide Hydrolase (sEH) Inhibitory Activity. [PDF]

Plants (Basel)
Sun Y, Fan C, Chen L, Cui X, Otsuki K, Zhang M, Qiu F, Ding L, Li W.   +8 more
europepmc   +1 more source

Improving Hydrolytic Activity and Enantioselectivity of Epoxide Hydrolase from Phanerochaete chrysosporium by Directed Evolution. [PDF]

Molecules
Shao H, Xu P, Tao X, He X, Pu C, Liang S, Shi Y, Wang X, Feng H, Yong B.   +9 more
europepmc   +1 more source

Soluble Epoxide Hydrolase Inhibition Improves Alzheimer's Disease Hallmarks: Correlation with Peripheral Inflammation and Gut Microbiota Modulation. [PDF]

Aging Dis
Jarne-Ferrer J, Griñán-Ferré C, Jora B, Codony S, Miró L, Rosell-Cardona C, Miñana-Galbis D, Pérez-Bosque A, Vazquez S, Pallàs M.   +9 more
europepmc   +1 more source

Inhibitors of soluble epoxide hydrolase and cGAS/STING repair defects in amyloid-β clearance underlying vascular complications of Alzheimer's disease. [PDF]

J Alzheimers Dis
Fiala M, Hammock BD, Hwang SH, Whitelegge J, Paul K, Kaczor-Urbanowicz KE, Urbanowicz A, Kesari S.   +7 more
europepmc   +1 more source