Results 111 to 120 of about 67,478 (222)

Association between the soluble epoxide hydrolase gene and preeclampsia

Hypertension in Pregnancy, 2017
Objective: In this study the association between K55R polymorphism, methylation level of the EPHX2 promoter region, and PE was investigated in 520 individuals including 260 PE patients and 260 healthy pregnant women.
Ismail Sari, Hatice Pinarbasi, Ergun Pinarbasi, Caglar Yildiz   +3 more
doaj   +1 more source

Liver Soluble Epoxide Hydrolase Regulates Behavioral and Cellular Effects of Chronic Stress

Cell Reports, 2019
Summary: Major depression is a serious global health concern; however, the pathophysiology underlying this condition remains unclear. While numerous studies have focused on brain-specific mechanisms, few have evaluated the role of peripheral organs in ...
Xi-He Qin, Zhou Wu, Jing-Hua Dong, Yuan-Ning Zeng, Wen-Chao Xiong, Ce Liu, Meng-Yao Wang, Min-Zhen Zhu, Wen-Jun Chen, Yuan Zhang, Qi-Yuan Huang, Xin-Hong Zhu   +11 more
doaj   +1 more source

Role of the soluble epoxide hydrolase and cytochrome P450-derived epoxyeicosatrienoic acids in hypoxic pulmonary vasoconstriction and hypoxia-induced pulmonary vascular remodelling [PDF]

, 2009
Hypoxic pulmonary vasoconstriction (HPV) redistributes pulmonary blood flow from areas of low oxygen partial pressure to areas of normal or relativity high oxygen availability, thus optimising the matching of perfusion to ventilation and preventing ...
Keserü, Benjamin
core  

Supplementary Table 1 from Genetically Lowered Microsomal Epoxide Hydrolase Activity and Tobacco-Related Cancer in 47,000 Individuals

, 2011
Supplementary Table 1 from Genetically Lowered Microsomal Epoxide Hydrolase Activity and Tobacco-Related Cancer in 47,000 ...
Morten Dahl (250510), Julie Lee (88547), Børge G. Nordestgaard (7672265)   +2 more
core   +1 more source

Flow chart of study selection. CNKI, Chinese National Knowledge Infrastructure; mEH, microsomal epoxide hydrolase; HCC, hepatocellular carcinoma.

, 2013
Flow chart of study selection. CNKI, Chinese National Knowledge Infrastructure; mEH, microsomal epoxide hydrolase; HCC, hepatocellular carcinoma.
Le-Qun Li (179464), Gui-Sheng Xie (381909), Liang Ma (37793), Xue-Mei You (179426), Jian-Hong Zhong (179419), Bang-De Xiang (381908)   +5 more
core   +1 more source

Supplementary Figure 1 from Genetically Lowered Microsomal Epoxide Hydrolase Activity and Tobacco-Related Cancer in 47,000 Individuals

, 2011
Supplementary Figure 1 from Genetically Lowered Microsomal Epoxide Hydrolase Activity and Tobacco-Related Cancer in 47,000 ...
Morten Dahl (250510), Julie Lee (88547), Børge G. Nordestgaard (7672265)   +2 more
core   +1 more source

Regulation Roles of Juvenile Hormone Epoxide Hydrolase Gene 2 in the Female River Prawn Macrobrachium nipponense Reproductive Process

Current Issues in Molecular Biology
In this study, we investigated the regulatory roles of the juvenile hormone epoxide hydrolase (JHEH) gene in the reproductive process of female Macrobrachium nipponense. Its total cDNA length was 1848 bp, encoding for 460 amino acids.
Jisheng Wang, Mengying Zhang, Hongtuo Fu, Wenyi Zhang, Yiwei Xiong, Shubo Jin, Hui Qiao, Sufei Jiang   +7 more
doaj   +1 more source

Preclinical evaluation of EPHX2 inhibition as a novel treatment for inflammatory bowel disease.

PLoS ONE, 2019
Epoxyeicosatrienoic acids (EETs) are signaling lipids produced by cytochrome P450 epoxygenation of arachidonic acid, which are metabolized by EPHX2 (epoxide hydrolase 2, alias soluble epoxide hydrolase or sEH).
William C Reisdorf, Qing Xie, Xin Zeng, Wensheng Xie, Neetu Rajpal, Bao Hoang, Mark E Burgert, Vinod Kumar, Mark R Hurle, Deepak K Rajpal, Sarah O'Donnell, Thomas T MacDonald, Anna Vossenkämper, Lin Wang, Mike Reilly, Bart J Votta, Yolanda Sanchez, Pankaj Agarwal   +17 more
doaj   +1 more source

Characterization of the epoxide hydrolase from an epichlorohydrin-degrading Pseudomonas sp.

, 1991
An epoxide hydrolase was purified to homogeneity from the epichlorohydrin-utilizing bacterium Pseudomonas sp. strain AD1. The enzyme was found to be a monomeric protein with a molecular mass of 35 kDa.
Jacobs, Mariken H.J., Janssen, Dick B., van den Wijngaard, Abraham, Pentenga, Marjan   +3 more
core   +1 more source

Catalytic mechanism of limonene epoxide hydrolase : a theoretical study

, 2005
The catalytic mechanism of limonene epoxide hydrolase (LEH) was investigated theoretically using the density functional theory method B3LYP. LEH is part of a novel limonene degradation pathway found in Rhodococcus erythropolis DCL14, where it catalyzes ...
Himo, Fahmi,, Hopmann, Kathrin H.,, Hallberg, B. Martin,, Hopmann, KH, Hallberg, BM, Himo, F   +5 more
core   +1 more source