Liver Soluble Epoxide Hydrolase Regulates Behavioral and Cellular Effects of Chronic Stress
Cell Reports, 2019 Summary: Major depression is a serious global health concern; however, the pathophysiology underlying this condition remains unclear. While numerous studies have focused on brain-specific mechanisms, few have evaluated the role of peripheral organs in ...
Xi-He Qin +11 more
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An epoxide hydrolase from endophyticStreptomycesshows unique structural features and wide biocatalytic activity [PDF]
, 2020 Gabriela D. Tormet‐González +5 more
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Increases in Levels of Epoxyeicosatrienoic and Dihydroxyeicosatrienoic Acids (EETs and DHETs) in Liver and Heart in Vivo by 2,3,7,8-Tetrachlorodibenzo-p-Dioxin (TCDD) and in Hepatic EET:DHET Ratios by Cotreatment with TCDD and the Soluble Epoxide Hydrolase Inhibitor AUDA [PDF]
, 2013 Silvia Diani-Moore +3 more
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Preclinical evaluation of EPHX2 inhibition as a novel treatment for inflammatory bowel disease.
PLoS ONE, 2019 Epoxyeicosatrienoic acids (EETs) are signaling lipids produced by cytochrome P450 epoxygenation of arachidonic acid, which are metabolized by EPHX2 (epoxide hydrolase 2, alias soluble epoxide hydrolase or sEH).
William C Reisdorf +17 more
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Inhibition of Soluble Epoxide Hydrolase Attenuates Bosutinib-Induced Blood Pressure Elevation [PDF]
, 2021 Zhen Cui +10 more
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Isothermal Titration Calorimetry Enables Rapid Characterization of Enzyme Kinetics and Inhibition for the Human Soluble Epoxide Hydrolase [PDF]
, 2019 Giancarlo Abis +3 more
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Soybean Epoxide Hydrolase [PDF]
Journal of Biological Chemistry, 2005 Elizabeth Blée +5 more
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