Cloning and Characterization of Drosophila melanogaster Juvenile Hormone Epoxide Hydrolases (JHEH) and Their Promoters [PDF]
Biomolecules, 2022 Juvenile hormone epoxide hydrolase (JHEH) plays an important role in the metabolism of JH III in insects. To study the control of JHEH in female Drosophila melanogaster, JHEH 1, 2 and 3 cDNAs were cloned and sequenced.
Dov Borovsky +6 more
doaj +2 more sources
Role of epoxy-fatty acids and epoxide hydrolases in the pathology of neuro-inflammation. [PDF]
Biochimie, 2019 Neuroinflammation is a physiologic response aimed at protecting the central nervous system during injury. However, unresolved and chronic neuroinflammation can lead to long term damage and eventually neurologic disease including Parkinson's disease ...
Kodani SD, Morisseau C.
europepmc +2 more sources
Evolution of tunnels in α/β-hydrolase fold proteins-What can we learn from studying epoxide hydrolases? [PDF]
PLoS Computational Biology, 2022 The evolutionary variability of a protein's residues is highly dependent on protein region and function. Solvent-exposed residues, excluding those at interaction interfaces, are more variable than buried residues whereas active site residues are ...
Maria Bzówka +7 more
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Expanding the Catalytic Triad in Epoxide Hydrolases and Related Enzymes. [PDF]
ACS Catal, 2015 Potato epoxide hydrolase 1 exhibits rich enantio- and regioselectivity in the hydrolysis of a broad range of substrates. The enzyme can be engineered to increase the yield of optically pure products as a result of changes in both enantio- and ...
Amrein BA +7 more
europepmc +2 more sources
The prognostic significance of epoxide hydrolases in colorectal cancer [PDF]
Biochemistry and Biophysics ReportsColorectal cancer (CRC) is a common malignant cancer. Epoxide hydrolases (EHs) are involved in the development of cancer by regulating epoxides, but their relationship with CRC is unclear.
Lichao Cao +5 more
doaj +2 more sources
Compositional profile of α / β-hydrolase fold proteins in mangrove soil metagenomes: prevalence of epoxide hydrolases and haloalkane dehalogenases in oil-contaminated sites. [PDF]
Microb Biotechnol, 2015 The occurrence of genes encoding biotechnologically relevant α/β‐hydrolases in mangrove soil microbial communities was assessed using data obtained by whole‐metagenome sequencing of four mangroves areas, denoted BrMgv01 to BrMgv04, in São Paulo, Brazil ...
Jiménez DJ +5 more
europepmc +2 more sources
Time‐of‐Day Defines the Risk of Thermally Abused Frying Oil to Renal Injury by Modulating the Diurnal Dynamics of Oxylipins [PDF]
ExplorationModulation of circadian rhythms impairs homeostasis, resulting in altered susceptibility to disease development. New perspectives on nutrition emphasize the circadian timing of food intake.
Yanjun Liu +6 more
doaj +2 more sources
Primary Structure and Catalytic Mechanism of the Epoxide Hydrolase from Agrobacterium radiobacterAD1 [PDF]
, 1997 The epoxide hydrolase gene from Agrobacterium radiobacter AD1, a bacterium that is able to grow on epichlorohydrin as the sole carbon source, was cloned by means of the polymerase chain reaction with two degenerate primers based on the N-terminal and C ...
Rick Rink +4 more
core +9 more sources
Enzymes from Extreme Environments and their Industrial Applications [PDF]
Frontiers in Bioengineering and Biotechnology, 2015 This article will discuss the importance of specific extremophilic enzymes for applications in industrial biotechnology. It will specifically address those enzymes that have applications in the area of biocatalysis.
Jennifer Ann Littlechild
doaj +5 more sources
Characterization of an isobutylene epoxide hydrolase (IbcK) from the isobutylene-catabolizing bacterium Mycolicibacterium sp. ELW1 [PDF]
Applied and Environmental MicrobiologyIsobutylene (IB) is produced on a large scale by the petrochemical industry and is metabolized by the aerobic alkene-metabolizing bacterium Mycolicibacterium sp. ELW1. The initial metabolite of IB catabolism by this bacterium is proposed to be 2-methyl-1,
Nicholas W. Faulkner +6 more
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