Results 91 to 100 of about 4,873 (155)

Monolayer autoxidation of arachidonic acid to epoxyeicosatrienoic acids as a model of their potential formation in cell membranes. [PDF]

J Lipid Res, 2022
Weiny JA, Boeglin WE, Calcutt MW, Stec DF, Brash AR.   +4 more
europepmc   +1 more source

Epoxyeicosatrienoic Acids Inhibit the Activation of Murine Fibroblasts by Blocking the TGF-β1-Smad2/3 Signaling in a PPARγ-Dependent Manner. [PDF]

Oxid Med Cell Longev, 2022
Tao JH, Liu T, Zhang CY, Zu C, Yang HH, Liu YB, Yang JT, Zhou Y, Guan CX.   +8 more
europepmc   +1 more source

Cyp2c44 epoxygenase-derived epoxyeicosatrienoic acids in vascular smooth muscle cells elicit vasoconstriction of the murine ophthalmic artery. [PDF]

Sci Rep, 2021
Hu J, Sisignano M, Brecht R, Perumal N, Angioni C, Bibli IS, Fisslthaler B, Kleinert H, Pfeiffer N, Fleming I, Manicam C.   +10 more
europepmc   +1 more source

Correction to: Effects of angiotensin II receptor blockers on serum levels of epoxyeicosatrienoic acids and dihydroxyeicosatrienoic acids in patients admitted to a cardiovascular center. [PDF]

Eur J Clin Pharmacol, 2021
Kato Y, Senda A, Mukai Y, Yamashita M, Sasaoka Y, Hanada M, Hongo F, Hirokami M, Rane A, Inotsume N, Toda T.   +10 more
europepmc   +1 more source

Dimethoxybenzohomoadamantane-based soluble epoxide hydrolase inhibitors: in vivo efficacy in a murine model of chemotherapy-induced neuropathic pain

Journal of Enzyme Inhibition and Medicinal Chemistry
The soluble epoxide hydrolase (sEH) has recently emerged as a promising target for the treatment of several pain-related conditions. Herein, we report the design and synthesis of a peripherally restricted sEH inhibitor with high potency and good Drug ...
Sandra Codony, Beatrice Jora, Miriam Santos-Caballero, Qiongju Qiu, Carla Calvó-Tusell, Celia Escriche, Andreea L. Turcu, Filippo Prischi, Clara Bartra, Cristina Val, Christophe Morisseau, Belén Pérez, Andrea Bertran-Mostazo, Sílvia Osuna, Rubén Corpas, Christian Griñán-Ferré, Carles Galdeano, M. Isabel Loza, Mercè Pallàs, Coral Sanfeliu, Bruce D. Hammock, José Brea, Ferran Feixas, Maria R. Conte, Enrique J. Cobos, Santiago Vázquez   +25 more
doaj   +1 more source

Effects of angiotensin II receptor blockers on serum levels of epoxyeicosatrienoic acids and dihydroxyeicosatrienoic acids in patients admitted to a cardiovascular center. [PDF]

Eur J Clin Pharmacol, 2021
Kato Y, Senda A, Mukai Y, Yamashita M, Sasaoka Y, Hanada M, Hongo F, Hirokami M, Rane A, Inotsume N, Toda T.   +10 more
europepmc   +1 more source

Evaluation of the Therapeutic Potential of Sulfonyl Urea Derivatives as Soluble Epoxide Hydrolase (sEH) Inhibitors

Molecules
The inhibition of soluble epoxide hydrolase (sEH) can reduce the level of dihydroxyeicosatrienoic acids (DHETs) effectively maintaining endogenous epoxyeicosatrienoic acids (EETs) levels, resulting in the amelioration of inflammation and pain ...
Biswajit Kundu, Szabolcs Dvorácskó, Abhishek Basu, Lenny Pommerolle, Kyu Ah Kim, Casey M. Wood, Eve Gibbs, Madeline Behee, Nadya I. Tarasova, Resat Cinar, Malliga R. Iyer   +10 more
doaj   +1 more source

Epoxyeicosatrienoic Acid [PDF]

, 2020
openaire   +1 more source

New Alkoxy- Analogues of Epoxyeicosatrienoic Acids Attenuate Cisplatin Nephrotoxicity In Vitro via Reduction of Mitochondrial Dysfunction, Oxidative Stress, Mitogen-Activated Protein Kinase Signaling, and Caspase Activation. [PDF]

Chem Res Toxicol, 2021
Singh N, Vik A, Lybrand DB, Morisseau C, Hammock BD.   +4 more
europepmc   +1 more source

Increased Epoxyeicosatrienoic Acids and Hydroxyeicosatetraenoic Acids After Treatment of Iodide Intake Adjustment and 1,25-Dihydroxy-Vitamin D₃ Supplementation in High Iodide Intake-Induced Hypothyroid Offspring Rats. [PDF]

Front Physiol, 2021
Liu Q, Zhang Y, Zhao H, Yao X.
europepmc   +1 more source