Endogenous epoxyeicosatrienoic acids
A Karara +4 more
openaire +1 more source
5.1 EPOXYEICOSATRIENOIC ACIDS IN THE REGULATION OF VASCULAR TONE
L. Yang +3 more
doaj +1 more source
Endothelial epoxyeicosatrienoic acid release is intact in aldosterone excess
BACKGROUND AND AIMS Endothelial dysfunction (ED) is considered to be a major driver of the increased incidence of cardiovascular disease in primary aldosteronism (PA). The functionality of the epoxyeicosatrienoic acid (EET) pathway, involving the release of beneficial endothelium-derived lipid mediators, in PA is unknown. Evidence suggests this pathway
Meng, Yao +16 more
openaire +4 more sources
Inhibition of soluble epoxide hydrolase ameliorates renal injury in IgA nephropathy by restoring epoxyeicosatrienoic acids. [PDF]
Yin HH +18 more
europepmc +1 more source
CYP2J2-produced epoxyeicosatrienoic acids contribute to the ferroptosis resistance of pancreatic ductal adenocarcinoma in a PPARγ-dependent manner. [PDF]
Tao P, Jiang Y, Wang H, Gao G.
europepmc +1 more source
Epoxyeicosatrienoic acids protect airway epithelial mitochondria by activating the cAMP/PKA-DRP1 Ser637 axis in cigarette smoke-induced lung injury. [PDF]
Li Y +12 more
europepmc +1 more source
Putative receptors and signaling pathways responsible for the biological actions of epoxyeicosatrienoic acids. [PDF]
Edin ML, Graves JP, Zeldin DC.
europepmc +1 more source
Epoxyeicosatrienoic acids (EETs): A novel class of second messengers of hormonal functional responses. [PDF]
Capdevila JH, Falck JR, Adebesin AM.
europepmc +1 more source
CYP2J2-derived epoxyeicosatrienoic acids protect against doxorubicin-induced cardiotoxicity by reducing oxidative stress and apoptosis via activation of the AMPK pathway. [PDF]
Zhu C +5 more
europepmc +1 more source

