Results 51 to 60 of about 10,597 (237)

Perioperative use of Epsilon-aminocaproic acid in patients with the diagnosis of prostatic benign hyperplasia

Revista Cubana de Anestesiología y Reanimación, 2016
Introduction: To reduce intraoperative blood loss and the use of transfusion requirements, antifibrinolytic agents that repermeabilize a bleeding vessel are used.
Zaily Fuentes Díaz, Orlando Bismark Rodríguez Salazar, Sarah López Lazo   +2 more
doaj   +2 more sources

Antifibrinolíticos e cirurgia cardíaca com circulação extracorpórea Antifibrinolíticos y cirugía cardíaca con circulación extracorpórea Antifibrinolytics and cardiac surgery with cardiopulmonary bypass

Revista Brasileira de Anestesiologia, 2007
JUSTIFICATIVA E OBJETIVOS: A cirurgia cardíaca é a especialidade cirúrgica que com mais freqüência está associada a sangramento, coagulopatia e necessidade de derivados de sangue.
Ari-Tadeu Lírio dos Santos, João Carlos Splettstosser, Paulo Warpechowski, Mariana Mariz Pinto Gaidzinski   +3 more
doaj   +1 more source

Group B Streptococcus hijacks the host plasminogen system to promote brain endothelial cell invasion. [PDF]

PLoS ONE, 2013
Group B Streptococcus (GBS) is the leading cause of meningitis in neonates. We have previously shown that plasminogen, once recruited to the GBS cell surface and converted into plasmin by host-derived activators, leads to an enhancement of bacterial ...
Vanessa Magalhães, Elva Bonifácio Andrade, Joana Alves, Adilia Ribeiro, Kwang Sik Kim, Margarida Lima, Patrick Trieu-Cuot, Paula Ferreira   +7 more
doaj   +1 more source

Plasmin Regulation through Allosteric, Sulfated, Small Molecules [PDF]

, 2015
Plasmin, a key serine protease, plays a major role in clot lysis and extracellular matrix remodeling. Heparin, a natural polydisperse sulfated glycosaminoglycan, is known to allosterically modulate plasmin activity.
Al-Horani, Rami A., Desai, Umesh R., Karuturi, Rajesh, White, Domonique T.   +3 more
core   +3 more sources

Towards an Analytical Procedure Control Strategy for the Capillary Zone Electrophoresis Method for Monoclonal Antibodies: Alternatives for ε‐Aminocaproic Acid and Triethylenetetramine

ELECTROPHORESIS, Volume 46, Issue 23, Page 1645-1650, December 2025.
ABSTRACT The ICH guideline Q14 on analytical procedure development underlines the importance of science and risk‐based methods for the evaluation of the quality of medicines. Ultimately, a pharmaceutical company, the sponsor, is responsible that the analytical method is fit‐for‐purpose during routine use throughout its lifecycle. Part of the analytical
Joanne Baxter, Lori Fitton, Cari E. Sänger ‐ van de Griend   +2 more
wiley   +1 more source

Antifibrinolytics in liver surgery

Indian Journal of Anaesthesia, 2010
Hyperfibrinolysis, a known complication of liver surgery and orthotopic liver transplantation (OLT), plays a significant role in blood loss. This fact justifies the use of antifibrinolytic drugs during these procedures.
Jalpa Makwana, Saloni Paranjape, Jyotsna Goswami   +2 more
doaj   +1 more source

The Concise Guide to PHARMACOLOGY 2025/26: Enzymes

British Journal of Pharmacology, Volume 182, Issue S1, Page S307-S403, December 2025.
The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander, Doriano Fabbro, Alasdair J. Gibb, Eamonn Kelly, Alistair A. Mathie, Chloe J. Peach, Emma L. Veale, Jane F. Armstrong, Elena Faccenda, Simon D. Harding, Christopher Southan, Jamie A. Davies, Stephanie Annett, Detlev Boison, Kathryn Elisa Burns, Carmen Dessauer, Jürg Gertsch, Nuala Ann Helsby, Angelo A. Izzo, Rennolds Ostrom, Ester Pagano, Andreas Papapetropoulos, Nigel J. Pyne, Susan Pyne, Tracy Robson, Roland Seifert, Johannes‐Peter Stasch, Csaba Szabo, Mario van der Stelt, Albert van der Vliet, Val Watts, Szu Shen Wong   +31 more
wiley   +1 more source

Prevention and Treatment of Hemorrhagic Cystitis [PDF]

, 1997
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/90047/1/j.1875-9114.1997.tb03745.x ...
West, Nina J.
core   +1 more source

Massive Bleeding as the First Clinical Manifestation of Metastatic Prostate Cancer due to Disseminated Intravascular Coagulation with Enhanced Fibrinolysis

Case Reports in Hematology, 2016
Disseminated intravascular coagulation (DIC) is the most frequent coagulation disorder associated with metastatic prostate adenocarcinoma. However, DIC with enhanced fibrinolysis as an initial presentation of prostate cancer is extremely rare.
Mónica Palma Anselmo, Gustavo Nobre de Jesus, João Madeira Lopes, Rui M. M. Victorino, João Meneses Santos   +4 more
doaj   +1 more source

Comparison of Tranexamic Acid and Aminocaproic Acid in Coronary Bypass Surgery [PDF]

, 2016
OBJECTIVE: Tranexamic acid (TXA) and ɛ-aminocaproic acid (EACA) are used in coronary bypass surgery for antifibrinolytic therapy. Since the removal of aprotinin, data directly comparing their blood sparing effect and their side effects is still missing ...
LeCleir, Lisa K
core   +1 more source