Abstract Climate change is expected to alter the input of nitrogen (N) sources in the Eastern Canadian Arctic Archipelago and Baffin Bay due to increased discharge from glacial meltwater and permafrost thaw. Since dissolved inorganic N is generally depleted in surface waters, dissolved organic N (DON) could represent a significant N source fueling ...
H. C. Westbrook+6 more
wiley +1 more source
The establishment of reference intervals for the ClotPro thromboelastometry device in healthy dogs
Abstract Objective To establish reference intervals using a new point‐of‐care thromboelastometry device in dogs for the extrinsically activated test (EX‐test), intrinsically activated test (IN‐test), fibrin polymerization test (FIB‐test), ecarin test (ECA‐test), and tissue plasminogen activator test (TPA‐test) and to investigate the effects of storage ...
Samantha K. Day+4 more
wiley +1 more source
Réduire les pertes sanguines et les besoins transfusionnels en chirurgie pédiatrique [PDF]
Purpose: To summarize the physiology and pathophysiology relevant to perioperative blood loss in children. Strategies to reduce blood losses are reviewed.
Guay, Joanne+2 more
core
Re-Evaluation of the Role of Antifibrinolytic Therapy with Lysine Analogs in Liver Transplantation in The Post-Aprotinin Era [PDF]
Purpose of review: Hemorrhage, blood and blood product transfusions and the need for surgical re-exploration for bleeding can have a detrimental effect on patient outcome during liver surgery.
CONIGLIONE, FILADELFO+9 more
core +2 more sources
CE methods for charge variant analysis of mAbs and complex format biotherapeutics
Abstract Charge heterogeneity analysis of monoclonal antibodies (mAbs) and complex formats, such as bispecifics, is crucial for therapeutic applications. In this study, we developed two capillary electrophoresis (CE)‐based methods, capillary zone electrophoresis (CZE) and imaged capillary isoelectric focusing (iCIEF), for analyzing a broad spectrum of ...
Maximilian Meudt+5 more
wiley +1 more source
Orthotopic liver transplantation for fulminant and subacute hepatic failure [PDF]
Fulminant and subacute hepatitis are conditions characterized by rapid liver failure, which can lead to death in 80 to more than 95% of the cases with medical supportive care only.
Iwatsuki, S, Starzl, TE, Stieber, AC
core
ACVIM consensus statement on the treatment of immune thrombocytopenia in dogs and cats
Abstract Management of immune thrombocytopenia (ITP) in dogs and cats is evolving, but there are no evidence‐based guidelines to assist clinicians with treatment decisions. Likewise, the overall goals for treatment of ITP have not been established. Immunosuppressive doses of glucocorticoids are the first line treatment, but optimal treatment regimens ...
Dana N. LeVine+24 more
wiley +1 more source
روشهای مورد استفاده در کنترل خونریزی کبدی [PDF]
برقراری هموستاز سریع و مناسب در ارگان¬های پارانشیمی، خصوصاً در بافت کبدی کار بسیار دشواری می¬باشد. مشکل اصلی در کنترل خونریزی کبد، توقف تراوش خون از ساختار سینوزوئیدال بافت کبد می¬باشد که دارای عروق بسیار کوچکی می¬باشد و در نتیجه بستـن عـروق بسیار مشکل ...
شریف, محمد رضا+1 more
core
Hepatic artery thrombosis after pediatric liver transplantation a medical or surgical event [PDF]
Hepatic artery thrombosis (HAT) is one of the most serious complications after orthotopic liver transplan¬tation, and is associated with a high morbidity and mor¬tality.
Andrei, CS+10 more
core +1 more source
Identity verification of monoclonal antibodies by triple injection capillary zone electrophoresis
This paper presents an approach based on triple injection capillary zone electrophoresis for identification of monoclonal antibodies. The analyte to be identified is injected between two zones of a known reference. The distances between the reference zones (plug I and III) and the target zone (plug II) are adjusted by partial electrophoresis of the ...
Johan A. Carlsson+2 more
wiley +1 more source