Results 21 to 30 of about 40,852 (216)
Endoplasmic reticulum : shape and function in stress translation [PDF]
, 2014 The endoplasmic reticulum (ER) is a very versatile organelle. Besides its major role as the gateway to the secretory pathway the ER is central to adaptation against abiotic and biotic stress.
Stephen H. Howell +12 more
core +1 more source
Journal of Translational Medicine, 2023 Bone regeneration therapy is clinically important, and targeted regulation of endoplasmic reticulum (ER) stress is important in regenerative medicine. The processing of proteins in the ER controls cell fate.
Tingyu Wu +4 more
doaj +1 more source
Bidirectional crosstalk between endoplasmic reticulum stress and mTOR signaling [PDF]
, 2012 Many cellular processes including apoptosis, autophagy, translation, energy metabolism, and inflammation are controlled by the mammalian target of rapamycin (mTOR) kinase and the endoplasmic reticulum (ER) stress pathway, also known as the unfolded ...
Appenzeller-Herzog, Christian +1 more
core +1 more source
Antioxidants, 2021 In different pathological states that cause endoplasmic reticulum (ER) calcium depletion, altered glycosylation, nutrient deprivation, oxidative stress, DNA damage or energy perturbation/fluctuations, the protein folding process is disrupted and the ER ...
Yan Zhou +4 more
doaj +1 more source
Transcriptional analysis implicates endoplasmic reticulum stress in bovine spongiform encephalopathy. [PDF]
, 2010 Bovine spongiform encephalopathy (BSE) is a fatal, transmissible, neurodegenerative disease of cattle. To date, the disease process is still poorly understood.
Xiang, Wei +10 more
core +1 more source
MFN2 mediates ER-mitochondrial coupling during ER stress through specialized stable contact sites
Frontiers in Cell and Developmental Biology, 2022 Endoplasmic reticulum (ER) functions critically depend on a suitable ATP supply to fuel ER chaperons and protein trafficking. A disruption of the ability of the ER to traffic and fold proteins leads to ER stress and the unfolded protein response (UPR ...
Benjamin Gottschalk +6 more
doaj +1 more source
A wash-free ER marker to monitor micropolarity during ER stress and visualize ER- Golgi transport
, 2023 Cellular stress plays a key role to regulate and maintain organismal as well as microenvironmental homeostasis. The stress-induced response is also reflected in the micropolarity of any specific cellular compartment, which is essential to be quantified ...
Apurba Lal, Koner +3 more
core +1 more source
The endoplasmic reticulum in plant immunity and cell death [PDF]
, 2012 The endoplasmic reticulum (ER) is a highly dynamic organelle in eukaryotic cells and a major production site of proteins destined for vacuoles, the plasma membrane, or apoplast in plants.
Ruth eEichmann +5 more
core +1 more source
MicroRNA-494 Regulates Endoplasmic Reticulum Stress in Endothelial Cells
Frontiers in Cell and Developmental Biology, 2021 Defects in stress responses are important contributors in many chronic conditions including cancer, cardiovascular disease, diabetes, and obesity-driven pathologies like non-alcoholic steatohepatitis (NASH).
Namita Chatterjee +5 more
doaj +1 more source
The genetic architecture of the genome-wide transcriptional response to ER stress in the mouse.
PLoS Genetics, 2015 Endoplasmic reticulum (ER) stress occurs when misfolded proteins accumulate in the ER. The cellular response to ER stress involves complex transcriptional and translational changes, important to the survival of the cell.
Clement Y Chow +4 more
doaj +1 more source