Results 51 to 60 of about 1,305,585 (286)

Regulation of endoplasmic reticulum stress in models of kidney disease

open access: yesAdvances in Redox Research, 2021
Endoplasmic reticulum (ER) stress is induced by intrinsic and extrinsic factors and, in consequence, activates the unfolded protein response (UPR); which in an acute phase restores cellular homeostasis, whereas in a chronic phase promotes apoptosis.
Tania Gómez-Sierra   +4 more
doaj   +1 more source

The Induction of Dendritic Cell Endoplasmic Reticulum Stress by Irradiated-Tumor Derived Extracellular Vesicles Supports the Adoption of a Pro-Tumor Phenotype [PDF]

open access: yes, 2020
The Induction of Macrophage Endoplasmic Reticulum Stress by Irradiated-Tumor Derived Extracellular Vesicles Supports the Adoption of a Pro-Tumor Phenotype Sitara Mahmoodi, Depts. of Biology and Chemistry, with Dr. Sarah Golding, Dept.
Mahmoodi, Sitara
core   +1 more source

Endoplasmic reticulum involvement in yeast cell death [PDF]

open access: yes, 2012
Yeast cells undergo programed cell death (PCD) with characteristic markers associated with apoptosis in mammalian cells including chromatin breakage, nuclear fragmentation, reactive oxygen species generation, and metacaspase activation.
Austriaco, Nicanor
core   +3 more sources

The Role of Endoplasmic Reticulum Stress Response in Male Reproductive Physiology and Pathology: A Review

open access: yesThe World Journal of Men's Health, 2020
Endoplasmic reticulum (ER) stress, defined as prolonged disturbances in protein folding and accumulation of unfolded proteins in the ER. Perturbation of the ER, such as distribution of oxidative stress, iron imbalance, Ca2+ leakage, protein overload ...
Keshab Kumar Karna   +4 more
doaj   +1 more source

Deep Learning-Based Morphological Classification of Endoplasmic Reticulum Under Stress

open access: yesFrontiers in Cell and Developmental Biology, 2022
Endoplasmic reticulum stress (ER stress) is a condition that is defined by abnormal accumulation of unfolded proteins. It plays an important role in maintaining cellular protein, lipid, and ion homeostasis.
Yuanhao Guo   +14 more
doaj   +1 more source

ER stress in antigen‐presenting cells promotes NKT cell activation through endogenous neutral lipids [PDF]

open access: yes, 2020
CD1d-restricted invariant natural killer T (iNKT) cells constitute a common glycolipid-reactive innate-like T-cell subset with a broad impact on innate and adaptive immunity.
Cheng, Tan‐Yun   +12 more
core   +2 more sources

Obesity and endoplasmic reticulum (ER) stresses [PDF]

open access: yesFrontiers in Immunology, 2012
In obesity, the adipose cells behave as inflammatory source and result to low grade inflammation. This systemic inflammation along with oxidative stress is a silent killer and damages other vital organs also. High metabolic process, induced due to high nutritional intake, results to endoplasmic reticulum (ER) stress and mitochondrial stress.
Tripathi, Yamini B., Pandey, Vivek
openaire   +3 more sources

THE ESSENTIAL BIOLOGY OF THE ENDOPLASMIC RETICULUM STRESS RESPONSE FOR STRUCTURAL AND COMPUTATIONAL BIOLOGISTS

open access: yesComputational and Structural Biotechnology Journal, 2013
The endoplasmic reticulum (ER) stress response is a cytoprotective mechanism that maintains homeostasis of the ER by upregulating the capacity of the ER in accordance with cellular demands.
Sadao Wakabayashi, Hiderou Yoshida
doaj   +1 more source

Bifidobacteria Prevent Tunicamycin-Induced Endoplasmic Reticulum Stress and Subsequent Barrier Disruption in Human Intestinal Epithelial Caco-2 Monolayers. [PDF]

open access: yesPLoS ONE, 2016
Endoplasmic reticulum (ER) stress is caused by accumulation of unfolded and misfolded proteins in the ER, thereby compromising its vital cellular functions in protein production and secretion.
Takuya Akiyama   +2 more
doaj   +1 more source

Reticulons Regulate the ER Inheritance Block during ER Stress [PDF]

open access: yesDevelopmental Cell, 2016
Segregation of functional organelles during the cell cycle is crucial to generate healthy daughter cells. In Saccharomyces cerevisiae, ER stress causes an ER inheritance block to ensure cells inherit a functional ER. Here, we report that formation of tubular ER in the mother cell, the first step in ER inheritance, depends on functional symmetry between
Piña, Francisco Javier   +3 more
openaire   +4 more sources

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