Regulation of endoplasmic reticulum stress in models of kidney disease
Advances in Redox Research, 2021 Endoplasmic reticulum (ER) stress is induced by intrinsic and extrinsic factors and, in consequence, activates the unfolded protein response (UPR); which in an acute phase restores cellular homeostasis, whereas in a chronic phase promotes apoptosis.
Tania Gómez-Sierra +4 more
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Bifidobacteria Prevent Tunicamycin-Induced Endoplasmic Reticulum Stress and Subsequent Barrier Disruption in Human Intestinal Epithelial Caco-2 Monolayers. [PDF]
PLoS ONE, 2016 Endoplasmic reticulum (ER) stress is caused by accumulation of unfolded and misfolded proteins in the ER, thereby compromising its vital cellular functions in protein production and secretion.
Takuya Akiyama +2 more
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Deep Learning-Based Morphological Classification of Endoplasmic Reticulum Under Stress
Frontiers in Cell and Developmental Biology, 2022 Endoplasmic reticulum stress (ER stress) is a condition that is defined by abnormal accumulation of unfolded proteins. It plays an important role in maintaining cellular protein, lipid, and ion homeostasis.
Yuanhao Guo +14 more
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The Induction of Dendritic Cell Endoplasmic Reticulum Stress by Irradiated-Tumor Derived Extracellular Vesicles Supports the Adoption of a Pro-Tumor Phenotype [PDF]
, 2020 The Induction of Macrophage Endoplasmic Reticulum Stress by Irradiated-Tumor Derived Extracellular Vesicles Supports the Adoption of a Pro-Tumor Phenotype Sitara Mahmoodi, Depts. of Biology and Chemistry, with Dr. Sarah Golding, Dept.
Mahmoodi, Sitara
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Retinoic acid-induced differentiation sensitizes myeloid progenitors cells to ER stress [PDF]
, 2017 The clonal expansion of hematopoietic myeloid precursors blocked at different stages of differentiation characterizes the acute myeloid leukemia (AML) phenotype.
Capuano, Ernestina +7 more
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IRE1β negatively regulates IRE1α signaling in response to endoplasmic reticulum stress [PDF]
, 2020 IRE1β is an ER stress sensor uniquely expressed in epithelial cells lining mucosal surfaces. Here, we show that intestinal epithelial cells expressing IRE1β have an attenuated unfolded protein response to ER stress.
Acosta-Alvear +54 more
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Obesity and endoplasmic reticulum (ER) stresses [PDF]
Frontiers in Immunology, 2012 In obesity, the adipose cells behave as inflammatory source and result to low grade inflammation. This systemic inflammation along with oxidative stress is a silent killer and damages other vital organs also. High metabolic process, induced due to high nutritional intake, results to endoplasmic reticulum (ER) stress and mitochondrial stress.
Tripathi, Yamini B., Pandey, Vivek
openaire +3 more sources
The World Journal of Men's Health, 2020 Endoplasmic reticulum (ER) stress, defined as prolonged disturbances in protein folding and accumulation of unfolded proteins in the ER. Perturbation of the ER, such as distribution of oxidative stress, iron imbalance, Ca2+ leakage, protein overload ...
Keshab Kumar Karna +4 more
doaj +1 more source
HCV causes chronic endoplasmic reticulum stress leading to adaptation and interference with the unfolded protein response. [PDF]
PLoS ONE, 2011 BACKGROUND: The endoplasmic reticulum (ER) is the cellular site for protein folding. ER stress occurs when protein folding capacity is exceeded. This stress induces a cyto-protective signaling cascades termed the unfolded protein response (UPR) aimed at ...
Emmanuelle Merquiol +7 more
doaj +1 more source
Endoplasmic reticulum involvement in yeast cell death [PDF]
, 2012 Yeast cells undergo programed cell death (PCD) with characteristic markers associated with apoptosis in mammalian cells including chromatin breakage, nuclear fragmentation, reactive oxygen species generation, and metacaspase activation.
Austriaco, Nicanor
core +3 more sources