Identification of immune- and oxidative stress-related signature genes as potential targets for mRNA vaccines for pancreatic cancer patients. [PDF]
Li J +9 more
europepmc +1 more source
Exploring the Pathogenesis of Spondylarthritis beyond HLA-B27: A Descriptive Review. [PDF]
Nagit RE, Rezus E, Cianga P.
europepmc +1 more source
The inhibitory effect and targets of CRM197 on tumor growth in arsenic-transformed cells and lung cancer cells. [PDF]
Zhang X +9 more
europepmc +1 more source
Integrating plasma proteomics with genome-wide association data to identify novel drug targets for inflammatory bowel disease. [PDF]
Bai Z +9 more
europepmc +1 more source
Integrative mass spectrometry-driven multi-omics and single cell technologies in ankylosing spondylitis: insights into pathogenesis, biomarker discovery, and precision medicine. [PDF]
Gao Y, Li X, Luo F, Chen R, Zhang X.
europepmc +1 more source
Discovery of the First Selective Nanomolar Inhibitors of ERAP2 by Kinetic TargetāGuided Synthesis
AbstractEndoplasmic reticulum aminopeptidase 2 (ERAP2) is a key enzyme involved in the trimming of antigenic peptides presented by Major Histocompatibility Complex class I. It is a target of growing interest for the treatment of autoimmune diseases and in cancer immunotherapy.
Virgyl Camberlein, Sierocki Pierre
exaly +4 more sources
Association of an ERAP1 ERAP2 haplotype with familial ankylosing spondylitis
To assess whether there is excess transmission of alleles from the ERAP1 ERAP2 locus in families with ankylosing spondylitis (AS).199 multiplex families with AS with four non-synonymous single nucleotide polymorphisms (SNPs), three in the endoplasmic reticulum aminopeptidase 1 (ERAP1) gene (rs27044, rs10050860 and rs30187) and one in the endoplasmic ...
Nigil Haroon Mbbs,, Dm, John D Reveille
exaly +4 more sources

