Results 21 to 30 of about 2,350,327 (205)

L1CAM binds ErbB receptors through Ig-like domains coupling cell adhesion and neuregulin signalling. [PDF]

PLoS ONE, 2012
During nervous system development different cell-to-cell communication mechanisms operate in parallel guiding migrating neurons and growing axons to generate complex arrays of neural circuits.
Emanuelle Donier, Jose Antonio Gomez-Sanchez, Carmen Grijota-Martinez, Jarmila Lakomá, Sigrid Baars, Luis Garcia-Alonso, Hugo Cabedo   +6 more
doaj   +2 more sources

Synergistic antitumor activity of histone deacetylase inhibitors and anti-ErbB3 antibody in NSCLC primary cultures via modulation of ErbB receptors expression. [PDF]

Oncotarget, 2016
ErbB3, a member of the ErbB family receptors, has a key role in the development and progression of several cancers, including non-small cell lung cancer (NSCLC), and in the establishment of resistance to therapies, leading to the development of anti ...
Ciardiello C, Roca MS, Noto A, Bruzzese F, Moccia T, Vitagliano C, Di Gennaro E, Ciliberto G, Roscilli G, Aurisicchio L, Marra E, Mancini R, Budillon A, Leone A.   +13 more
europepmc   +2 more sources

ErbB receptors and their growth factor ligands in pediatric intestinal inflammation. [PDF]

Pediatr Res, 2014
The ErbB tyrosine kinases (epidermal growth factor receptor (EGFR), ErbB2/HER2, ErbB3, and ErbB4) are cell surface growth factor receptors widely expressed in many developing mammalian tissues, including in the intestinal tract.
Frey MR, Brent Polk D.
europepmc   +2 more sources

Profiling of ERBB receptors and downstream pathways reveals selectivity and hidden properties of ERBB4 antagonists [PDF]

iScience
Summary: ERBB receptor tyrosine kinases are involved in development and diseases like cancer, cardiovascular, neurodevelopmental, and mental disorders.
Lukša Popović, Jan P. Wintgens, Yuxin Wu, Ben Brankatschk, Sascha Menninger, Carsten Degenhart, Niels Jensen, Sven P. Wichert, Bert Klebl, Moritz J. Rossner, Michael C. Wehr   +10 more
doaj   +2 more sources

Promoter-level expression clustering identifies time development of transcriptional regulatory cascades initiated by ErbB receptors in breast cancer cells. [PDF]

Sci Rep, 2015
The analysis of CAGE (Cap Analysis of Gene Expression) time-course has been proposed by the FANTOM5 Consortium to extend the understanding of the sequence of events facilitating cell state transition at the level of promoter regulation.
Mina M, Magi S, Jurman G, Itoh M, Kawaji H, Lassmann T, Arner E, Forrest ARR, Carninci P, Hayashizaki Y, Daub CO, FANTOM Consortium, Okada-Hatakeyama M, Furlanello C.   +13 more
europepmc   +2 more sources

The Role of ErbB Receptors in Infection. [PDF]

Trends Microbiol, 2017
Ho J, Moyes DL, Tavassoli M, Naglik JR.
europepmc   +2 more sources

A Structural Insight Into Two Important ErbB Receptors (EGFR and HER2) and Their Relevance to Non-Small Cell Lung Cancer. [PDF]

Arch Pharm (Weinheim)
Topalan E, Büyükgüngör A, Çiğdem M, Güra S, Sever B, Otsuka M, Fujita M, Demirci H, Ciftci H.   +8 more
europepmc   +2 more sources

ERBB receptors: from oncogene discovery to basic science to mechanism-based cancer therapeutics. [PDF]

Cancer Cell, 2014
Arteaga CL, Engelman JA.
europepmc   +2 more sources

The spatiotemporal organization of ErbB receptors: insights from microscopy. [PDF]

Cold Spring Harb Perspect Biol, 2014
Valley CC, Lidke KA, Lidke DS.
europepmc   +2 more sources

Inactive ERBB receptors cooperate with reactive oxygen species to suppress cancer progression. [PDF]

Mol Ther, 2013
Hart MR, Su HY, Broka D, Goverdhan A, Schroeder JA.   +4 more
europepmc   +3 more sources