Results 111 to 120 of about 6,538 (228)

Molecular epidemiology and azole resistance mechanism study of Candida guilliermondii from a Chinese surveillance system

Scientific Reports, 2017
We studied the molecular epidemiology and mechanism of azole resistance of 164 C. guilliermondii isolates from a nationwide multi-center surveillance program.
Jing-Wei Cheng, Kang Liao, Timothy Kudinha, Shu-Ying Yu, Meng Xiao, He Wang, Fanrong Kong, Ying-Chun Xu   +7 more
doaj   +1 more source

The effectiveness of voriconazole in therapy of Candida glabratas biofilms oral infections and its influence on the matrix composition and gene expression [PDF]

, 2017
Candida glabrata is one of most prevalente yeast in fungal infections, especially in immunocompromised patients. Its azole resistance results in a low therapeutic response, particularly when associated with biofilms.
Azeredo, Joana, Gonçalves, Bruna, Henriques, Mariana, Rodrigues, Célia F., Rodrigues, M. Elisa, Silva, Sónia Carina   +5 more
core   +1 more source

First report of amphotericin B resistant Candida haemulonii isolated from the ICU of a referral hospital in Indonesia

Iranian Journal of Microbiology
Background and Objectives: Amphotericin B is a broad-spectrum antifungal agent commonly used to treat Candida haemulonii infection. C. haemulonii was isolated from patients reported to be intrinsically resistant to amphotericin B, encoded by the ERG2 ...
Rifdah Hanifah, Mardiastuti Wahid, Andi Yasmon   +2 more
doaj   +1 more source

Candida species biofilms' antifungal resistance [PDF]

, 2017
Candida infections (candidiasis) are the most prevalent opportunistic fungal infection on humans and, as such, a major public health problem. In recent decades, candidiasis has been associated to Candida species other than Candida albicans.
Albertson, Baillie, Baillie, Budtz-Jorgensen, Chiocchio, Fox, Goodman, Ho, Ivor, Jana, Knot, Kuhn, Lewis, Marie-Soleil, Mohan, Paige, Posteraro, Reid, Rex, Thomas, White, White   +21 more
core   +2 more sources

Transcriptome assembly and profiling of Candida auris reveals novel insights into biofilm-mediated resistance [PDF]

, 2018
Candida auris has emerged as a significant global nosocomial pathogen. This is primarily due to its antifungal resistance profile but also its capacity to form adherent biofilm communities on a range of clinically important substrates.
Ben-Ami, Berkow, Berkow, Bizerra, Bongomin, Borman, Borman, Calvo, Chatterjee, Chowdhary, Defosse, Denning, Dominguez, Fisher, Fonseca, Fox, Fu, Grahl, Haas, Hager, Hashemi, Hunter, Jeffery-Smith, Kean, Kean, Kean, Kean, Kempf, Kordalewska, Kordalewska, Larkin, Liu, Liu, Lockhart, Lohse, Martínez, Mukherjee, Naglik, Naglik, Nailis, Nobile, Perfect, Pierce, Rajendran, Rajendran, Rajendran, Ramage, Ramage, Ramage, Rodrigues, Ruiz-Gaitán, Schelenz, Sherry, Sherry, Silva, Soldini, Taff, Taff, Tumbarello, Tunney, Winter, Zarnowski, Zhao, Zhao   +63 more
core   +4 more sources

Mutations in TAC1 and ERG11 are major drivers of triazole antifungal resistance in clinical isolates of Candida parapsilosis [PDF]

, 2023
Laura A. Doorley, Katherine S. Barker, Qing Zhang, Jeffrey M. Rybak, P. David Rogers   +4 more
openalex   +1 more source

Characterization and phylogenetic analysis of a novel filamentous polymycovirus GbPmV1

mLife, Volume 4, Issue 5, Page 572-576, October 2025.
Hongjuan Bai, Linhao Song, Xin Luo, Weijie Chang, Jia Mi, Cheng Jin, Xiao Liu   +6 more
wiley   +1 more source

Harnessing Machine Learning to Uncover Hidden Patterns in Azole-Resistant CYP51/ERG11 Proteins

Microorganisms
Fungal resistance is a public health concern due to the limited availability of antifungal resources and the complexities associated with treating persistent fungal infections. Azoles are thus far the primary line of defense against fungi. Specifically, azoles inhibit the conversion of lanosterol to ergosterol, producing defective sterols and impairing
Otávio Guilherme Gonçalves de Almeida, Marcia Regina von Zeska Kress   +1 more
openaire   +3 more sources

RILEVAMENTO DI SNP NEL CODONE 464 DEL GENE ERG11 IN CANDIDA ALBICANS, MEDIANTE PYROSEQUENCING

Microbiologia Medica, 2004
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ORRU, GERMANO, Ciusa M. L, Pusceddu G, Montaldo C, COSENTINO, SOFIA, PISANO, MARIA BARBARA, Meroni E, PIRAS, VINCENZO, FADDA, MARIA ELISABETTA   +8 more
openaire   +4 more sources

MDR1 overexpression combined with ERG11 mutations induce high-level fluconazole resistance in Candida tropicalis clinical isolates

BMC Infectious Diseases, 2018
Background Marked increases in fluconazole resistance in Candida tropicalis have been recently reported. In this study, the molecular mechanisms behind fluconazole resistance were investigated. Methods Twenty-two C.
Longyang Jin, Zhuorui Cao, Qi Wang, Yichen Wang, Xiaojuan Wang, Hongbin Chen, Hui Wang   +6 more
doaj   +1 more source