Results 61 to 70 of about 6,538 (228)
Novel ERG11 and TAC1b Mutations Associated with Azole Resistance in Candida auris
Antimicrobial Agents and Chemotherapy, 2021 Candida auris is a novel Candida species that has spread in all continents, causing nosocomial outbreaks of invasive candidiasis. C. auris has the ability to develop resistance to all antifungal drug classes. Notably, many C. auris isolates are resistant to
Jizhou Li +5 more
openaire +3 more sources
Infection and Drug Resistance, 2022 Arome Solomon Odiba,1,2 Olanrewaju Ayodeji Durojaye,3– 5 Ifeoma Maureen Ezeonu,6 Anthony Christian Mgbeahuruike,7 Bennett Chima Nwanguma1,2 1Department of Biochemistry, Faculty of Biological Sciences, University of Nigeria, Nsukka, Enugu State, 410001 ...
Odiba AS +4 more
doaj
Resistance in Candida albicans: exploring the cell wall barrier by proteomics [PDF]
, 2015 The incidence of candidiasis has dramatically increased and bloodstream infections due to different species of Candida are becoming a prime cause of morbidity and mortality in different types of immunocompromised patients.
Angiolella, Letizia +2 more
core +1 more source
Antibiotics, 2021 Candida glabrata is one of the most prevalent causative pathogens of invasive candidiasis, and multidrug-resistant strains are emerging. We identified two clinical isolates of C. glabrata, BMU10720 and BMU10722 sequentially isolated from one patient with
Qiqi Wang +9 more
doaj +1 more source
Kajian Molekuler Resistensi Candida Albicans Terhadap Antifungi [PDF]
, 2014 Candida albicans is one of the species Candida which mostly cause infection in human. Antifungal agent azole, polyene, echinocandin, and flucytosine are commonly used for Candida albicans infection treatment.
Candrasari, D. S. (Damiana)
core +3 more sources
Contribution of Clinically Derived Mutations in ERG11 to Azole Resistance in Candida albicans [PDF]
Antimicrobial Agents and Chemotherapy, 2015 ABSTRACT In Candida albicans , the ERG11 gene encodes lanosterol demethylase, the target of the azole antifungals. Mutations in ERG11 that result in an amino acid substitution alter the abilities of the azoles to bind to and inhibit Erg11, resulting in ...
Stephanie A, Flowers +4 more
openaire +2 more sources
Microorganisms, 2019 Candida albicans is an opportunistic fungal pathogen of humans. Treatment of C. albicans infections relies on azoles, which target the lanosterol 14α-demethylase (Erg11p) encoded by the ERG11 gene.
Jakub Suchodolski +3 more
doaj +1 more source
Journal of Global Antimicrobial Resistance, 2020 Introduction: Fluconazole resistance in Candida tropicalis health care–associated infections is increasing. We investigated the role of efflux pump and mutations in ERG11p conferring fluconazole resistance in C. tropicalis. Materials and methods: A total
Nidhi Pandey +3 more
doaj +1 more source
Effect of voriconazole on Candida tropicalis biofilms: Relation with ERG genes expression [PDF]
, 2016 Candida tropicalis has emerged as the third most prevalent fungal pathogens and its ability to form biofilms has been considered one of the most important virulence factors, since biofilms represent high tolerance to antifungal agents.
C Luca De +29 more
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Immunity, Inflammation and Disease, 2021 Background Candida albicans, the main human fungal pathogen, can cause fungal infection and seriously affect people's health and life. This study aimed to investigate the effects of ritonavir (RIT) on C.
Wenli Feng +6 more
doaj +1 more source