Results 71 to 80 of about 6,538 (228)
Mapping the Cellular Response to Small Molecules Using Chemogenomic Fitness Signatures [PDF]
, 2013 Genome-wide characterization of the in vivo cellular response to perturbation is fundamental to understanding how cells survive stress. Identifying the proteins and pathways perturbed by small molecules affects biology and medicine by revealing the ...
Kaiser, Chris, Spear, Eric D.
core +1 more source
Pest Management Science, EarlyView.Here, we report for the first time a target site mutation in the CYP51 gene of the oilseed rape phoma stem canker fungus Plenodomus biglobosus (Leptosphaeria biglobosa) that is associated with decreased sensitivity to sterol demethylation inhibitor fungicides.
Kevin M King +4 more
wiley +1 more source
Antifungal Therapy: New Advances in the Understanding and Treatment of Mycosis [PDF]
, 2017 The high rates of morbidity and mortality caused by fungal infections are associated with the current limited antifungal arsenal and the high toxicity of the compounds.
Ana C. A. de Paula e Silva +8 more
core +1 more source
Yeast‐Based Biotechnology for Civilian Security
Environmental Microbiology Reports, Volume 18, Issue 1, February 2026.Yeasts constitute robust and versatile eukaryotic platforms for biotechnological applications relevant to civilian security. Both native and genetically engineered yeast systems enable sensitive detection of chemical and biological hazards, effective removal of metals and organic pollutants, and detoxification of mycotoxins.
Justyna Ruchała +2 more
wiley +1 more source
BMC Microbiology, 2009 Background Amino acid substitutions in the target enzyme Erg11p of azole antifungals contribute to clinically-relevant azole resistance in Candida albicans.
Ellis David +9 more
doaj +1 more source
Microbiology Resource Announcements, 2023 ABSTRACT Azoles are major antifungals in agriculture and medicine. However, the surge of intrinsic azole resistance is critical for public health. Here, we present the complete long-read sequencing of three azole-resistant Penicillium rubens from food crops.
Jeff Gauthier +7 more
openaire +2 more sources
Iranian Journal of Microbiology, 2023 Background and Objectives: Candida tropicalis is one of the major non-albicans species causing nosocomial infection. There is limited data about mechanisms of azole-resistance and virulence factors of Candida tropicalis.
Zahra Jahanshiri +2 more
doaj +1 more source
From data towards knowledge: Revealing the architecture of signaling systems by unifying knowledge mining and data mining of systematic perturbation data [PDF]
, 2013 Genetic and pharmacological perturbation experiments, such as deleting a gene and monitoring gene expression responses, are powerful tools for studying cellular signal transduction pathways.
Cowart, Ashley +3 more
core +3 more sources
Correlation between ERG11 Gene Mutations and Fluconazole Resistance in Candida albicans Strains Isolated from Rasht in Years 2015-2016 [PDF]
Majallah-i dānishgāh-i ̒ulūm-i pizishkī-i Arāk, 2017 Background: Candida albicans as an opportunistic fungal pathogen in human causes candidiasis. The widespread use of azoles has led to the increase of azole resistance in Candida albicans isolates.
Saeedeh Balabandi +2 more
doaj
Synthesis of new imidazole-based ionic liquids with antifungal activity against Candida albicans
Iranian Journal of Microbiology, 2023 Background and Objectives: Candida albicans cause a problematic condition in immunocompromised patients that could not be treated quickly due to the resistant behavior of microorganisms. This study aimed to investigate the effect of a novel ionic liquid
Amir Habibi +4 more
doaj +1 more source