Results 61 to 70 of about 3,777 (166)

Correlation between ERG11 Gene Mutations and Fluconazole Resistance in Candida albicans Strains Isolated from Rasht in Years 2015-2016 [PDF]

Majallah-i dānishgāh-i ̒ulūm-i pizishkī-i Arāk, 2017
Background: Candida albicans as an opportunistic fungal pathogen in human causes candidiasis. The widespread use of azoles has led to the increase of azole resistance in Candida albicans isolates.
Saeedeh Balabandi, Zeinab Khazaei-Koohpar, Najmeh Ranji   +2 more
doaj  

Evaluation of virulence factors and azole resistance mechanisms of Candida tropicalis isolates from head and neck cancer patients with OPC

Iranian Journal of Microbiology, 2023
Background and Objectives: Candida tropicalis is one of the major non-albicans species causing nosocomial infection. There is limited data about mechanisms of azole-resistance and virulence factors of Candida tropicalis.
Zahra Jahanshiri, Soheila Manifar, Farahnaz Hatami   +2 more
doaj   +1 more source

From Oral Candidiasis to Candidemia: A Review of Superficial to Invasive Progression

MicrobiologyOpen, Volume 15, Issue 4, August 2026.
Recent and limited evidence indicates that oral candidiasis can disseminate Candida albicans throughout the body, leading to invasive candidiasis, such as candidemia, a life‐threatening infection. Considering antifungal resistance and global outbreaks of emergent non‐albicans Candida and related yeasts, murine models help understand dissemination ...
Julia Robledo Jerez, Marcella Vieira Ambrosio, Marcela Eduarda Olegario Fernandes, Ewerton Garcia de Oliveira Mima   +3 more
wiley   +1 more source

Antifungal Potential of Cumin Spice Seeds, Cuminum cyminum, Against Aspergillus fumigatus: Mechanistic Insights Into Ergosterol, Melanin, and Biofilm Inhibition

Food Frontiers, Volume 7, Issue 4, July 2026.
Antifungal effects and underlying mechanism of the action of the supercritical fluid extracted from the cumin (Cuminum cyminum) seeds and its volatile phyto‐constituents against pathogenic Aspergillus fumigatus. ABSTRACT Spices are aromatic culinary ingredients used worldwide for enhancing food flavors, folklore therapy, and their antiseptic ...
Acharya Balkrishna, Lovely Gupta, Rani Singh, Yash Varshney, Rishabh Dev, Pardeep Nain, Savita Lochab, Anurag Varshney   +7 more
wiley   +1 more source

Structural basis for heterogeneous phenotype of ERG11 dependent Azole resistance in C.albicans clinical isolates [PDF]

SpringerPlus, 2014
Correlating antifungal Azole drug resistance and mis-sense mutations of ERG11 has been paradoxical in pathogenic yeast Candida albicans. Amino acid substitutions (single or multiple) are frequent on ERG11, a membrane bound enzyme of Ergosterol biosynthesis pathway. Presence or absence of mutations can not sufficiently predict susceptibility. To analyze
Debnath, Surajit, Addya, Soma
openaire   +2 more sources

Comparison of ERG11 gene expression profiles of Candida albicans treated with Thymus vulgaris extracts alone and in combination with Mentha spicata [PDF]

Biological Journal of Microorganism, 2018
Introduction:Diseases caused by opportunistic pathogen Candida albicans are usually treated with antifungal drugs, but treatment failure is not uncommon especially in profoundly immunocompromised hosts.
Alireza Khodavandi, Fahimeh Alizadeh, Zeynab Abrahe   +2 more
doaj   +1 more source

Synthesis of new imidazole-based ionic liquids with antifungal activity against Candida albicans

Iranian Journal of Microbiology, 2023
Background and Objectives: Candida albicans cause a problematic condition in immunocompromised patients that could not be treated quickly due to the resistant behavior of microorganisms. This study aimed to investigate the effect of a novel ionic liquid
Amir Habibi, Mansour Bayat, Behinb Omidi, Ali Ezabadi, Pejman Mortazavi   +4 more
doaj   +1 more source

WC1/WC2–Sre1 Transcriptional Cascade Controls Predation and Chlamydospore Formation in the Nematode‐Trapping Fungus Arthrobotrys flagrans

Microbial Biotechnology, Volume 19, Issue 7, July 2026.
Systematic functional characterization of all eight GATA‐type transcription factors in the nematode‐trapping fungus Arthrobotrys flagrans reveals a novel, light‐independent WC1/WC2–Sre1 transcriptional cascade that orchestrates both trap formation and chlamydospore development, providing actionable targets for engineering superior biocontrol strains ...
Yu Zhang, Jiafang Zuo, Qianfei Shi, Peiji Zhao, Hanbo Zhang, Minghe Mo, Guohong Li   +6 more
wiley   +1 more source

Role of ERG11 and MDR1 genes in cycloheximide and multidrug resistance in Candida species

Brazilian Journal of Microbiology
Candida species are amongst the commensals of the mucosal surfaces of the human body which include the oral cavity, vagina, and intestinal mucosa. Fungal infections are on the rise worldwide. The overall burden of infections due to fungi is difficult to estimate because the majority of them remain undiagnosed.
Zill-e- Huma, Sidrah Saleem, Muhammad Imran, Syed Mohsin Raza, Kokab Jabeen, Faiqa Arshad   +5 more
openaire   +2 more sources

In Vitro and In Vivo Effects of 14α-Demethylase ( ERG11 ) Depletion in Candida glabrata [PDF]

Antimicrobial Agents and Chemotherapy, 2001
ABSTRACT Sterol 14α-demethylase ( ERG11 ) is the target enzyme of azole antifungals that are widely used for the treatment of fungal infections. Candida glabrata is known to be less susceptible to fluconazole than most Candida albicans strains, and the ...
H, Nakayama, N, Nakayama, M, Arisawa, Y, Aoki   +3 more
openaire   +2 more sources