Sentinel Case of Candida auris in the Western United States Following Prolonged Occult Colonization in a Returned Traveler from India. [PDF]
Candida auris is an emerging multidrug-resistant yeast with high mortality. We report the sentinel C. auris case on the United States West Coast in a patient who relocated from India.
Crawford, Emily D +12 more
core +1 more source
Environmental azole fungicide, prochloraz, can induce cross-resistance to medical triazoles in Candida glabrata [PDF]
Acquisition of azole resistance by clinically relevant yeasts in nature may result in a significant, yet undetermined, impact in human health. The main goal of this study was to assess the development of cross-resistance between agricultural and clinical
Estevinho, Leticia M. +8 more
core +1 more source
Point mutations in the squalene epoxidase erg1 and sterol 14‐α demethylase erg11 gene of T indotineae isolates indicate that the resistant mutant strains evolved independently [PDF]
Anke Burmester +3 more
openalex +1 more source
The Roles of Plant MicroRNAs in Defence Against Pathogens
miRNAs modulate plant immunity against various pathogens, including fungi, bacteria, viruses, nematodes and oomycetes, by targeting pathogen effectors and modulating hormonal signalling. ABSTRACT MicroRNAs (miRNAs) are a class of noncoding RNAs that play important roles in regulating gene expression.
Abdou Mahaman Mahamadou +6 more
wiley +1 more source
Erg11mutations associated with azole resistance in clinical isolates ofCandida albicans [PDF]
The widespread use of azoles has led to increasing azole resistance among Candida albicans strains. One mechanism of azole resistance involves point mutations in the ERG11 gene, which encodes the target enzyme (cytochrome P450 lanosterol 14α-demethylase). In the present study, we amplified and sequenced the ERG11 gene of 23 C.
Ming-Jie, Xiang +7 more
openaire +2 more sources
Comparison of ERG11 gene expression profiles of Candida albicans treated with Thymus vulgaris extracts alone and in combination with Mentha spicata [PDF]
Introduction:Diseases caused by opportunistic pathogen Candida albicans are usually treated with antifungal drugs, but treatment failure is not uncommon especially in profoundly immunocompromised hosts.
Alireza Khodavandi +2 more
doaj +1 more source
Safety of Rhizomucor pusillus biomass powder as a novel food pursuant to Regulation (EU) 2015/2283
Abstract Following a request from the European Commission, the EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA) was asked to deliver an opinion on the safety of the Rhizomucor pusillus biomass powder as a novel food (NF) pursuant to Regulation (EU) 2015/2283. The NF is a filamentous fungus biomass powder. The novel food is intended for use
EFSA Panel on Nutrition +29 more
wiley +1 more source
Persistent Candida albicans colonization and molecular mechanisms of azole resistance in autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED) patients [PDF]
Objectives Patients with autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED, APS-I) suffer from chronic candidosis caused mainly by Candida albicans, and repeated courses of azole antifungals have led to the development of resistance ...
Bowyer, Paul +5 more
core
Repositioning Antimicrobial Peptides Against WHO‐Priority Fungi
The growing burden of drug‐resistant fungal infections, driven by pathogens such as Candida auris, Cryptococcus neoformans, and Aspergillus fumigatus, underscores the urgent need for novel antifungal therapies. This review explores antimicrobial peptides as promising agents with membrane‐disruptive activity, immunomodulatory properties, and delivery ...
Cesar Augusto Roque‐Borda +12 more
wiley +1 more source
Objective: To investigate the azole susceptibility of Candida albicans (C. albicans) from vulvovaginal candidosis patients and to analyze the relationship between ERG11 gene mutations in these isolates and azole resistance. Methods: Three hundred and two
Bin Wang +8 more
doaj +1 more source

